Legacy Protocols


PDB ID Structure ID UniProt ID Description HTML Link PDF Link
1T2A GMDS O60547 Crystal structure of human GDP-D-mannose 4,6-dehydratase HTML PDF
1TXJ Pk-TCTP P84152 Crystal structure of translationally controlled tumour-associated protein (TCTP) from Plasmodium knowlesi HTML PDF
1XCC Py-1Cys-PRX Q86SB3 1-Cys peroxidoxin from Plasmodium Yoelli HTML PDF
1XG5 MGC4172 Q6UWP2 Structure of human putative dehydrogenase MGC4172 in complex with NADP HTML PDF
1XL4 KirBac3.1 IS1 Q2W6R1 Intermediate gating structure 1 of the inwardly rectifying K+ channel KirBac3.1 HTML PDF
1XL6 KirBac3.1 IS2 D9N164 Intermediate gating structure 2 of the inwardly rectifying K+ channel KirBac3.1 HTML PDF
1XWS PIM1 P11309 Crystal Structure of the human PIM1 kinase domain HTML PDF
1Y6L UBE2E2 Q96LR5 Human ubiquitin conjugating enzyme E2E2 HTML PDF
1Y6Z Pf-HSP Q8IL32 Middle domain of Plasmodium falciparum putative heat shock protein PF14_0417 HTML PDF
1YB1 retSDR2 Q8NBQ5 Crystal structure of human 17-beta-hydroxysteroid dehydrogenase type XI HTML PDF
1YB5 CRYZ Q08257 Crystal structure of human Zeta-Crystallin with bound NADP HTML PDF
1YDE retSDR3 Q9BPX1 Crystal Structure of Human Retinal Short-Chain Dehydrogenase/Reductase 3 HTML PDF
1YH2 HSPC150 Q9NPD8 Ubiquitin-Conjugating Enzyme HSPC150 HTML PDF
1YH6 (superseded by 2Z5D) UBE2H P62256 Human ubiquitin-conjugating enzyme E2 H HTML PDF
1YLA HIP2 P61086 Ubiquitin-conjugating enzyme E2-25 kDa (Huntington interacting protein 2) HTML PDF
1YO3 (superseded by 5WOF) Pf-DNCL1 Q8I5R9 1.65 ANGSTROM STRUCTURE OF THE DYNEIN LIGHT CHAIN 1 FROM PLASMODIUM FALCIPARUM HTML PDF
1YQ7 FDPS P14324 Human farnesyl diphosphate synthase complexed with risedronate HTML PDF
1YQB UBQLN3 Q9H347 Human Ubiquilin 3 HTML PDF
1YRV MGC35130 Q5VVX9 Novel Ubiquitin-Conjugating Enzyme HTML PDF
1YV5 FDPS-Risedronate P14324 Human farnesyl diphosphate synthase complexed with Mg and risedronate HTML PDF
1YXM PECR Q9BY49 Crystal structure of peroxisomal trans 2-enoyl CoA reductase HTML PDF
1YZG ARL8 Q96KC2 Structure of Human ADP-ribosylation factor-like 8 HTML PDF
1Z4R GCN5L2 Q92830 Human GCN5 Acetyltransferase HTML PDF
1Z57 CLK1 P49759 Crystal structure of human CLK1 in complex with 10Z-Hymenialdisine HTML PDF
1Z6G Pf-GUK1 Q8I2M1 Crystal structure of guanylate kinase from Plasmodium falciparum HTML PDF
1Z6U NIRF Q96PU4 Np95-like ring finger protein isoform b [Homo sapiens] HTML PDF
1Z6X ARF4 P18085 Structure Of Human ADP-Ribosylation Factor 4 HTML PDF
1Z6Y ARL5 Q9Y689 Structure Of Human ADP-Ribosylation Factor-Like 5 HTML PDF
1Z6Z SPR P35270 Crystal Structure of Human Sepiapterin Reductase in complex with NADP+ HTML PDF
1Z7D Py-OAT Q7RT90 Ornithine aminotransferase PY00104 from Plasmodium Yoelii HTML PDF
1Z81 Py-PPI (PY00382) Q7RSH5 Crystal Structure of cyclophilin from Plasmodium yoelii. HTML PDF
1Z83 AK1 P00568 Crystal structure of human AK1A in complex with AP5A HTML PDF
1ZBQ 17β-HSD4 P51659 Crystal Structure Of Human 17-Beta-Hydroxysteroid Dehydrogenase Type 4 In Complex With NAD HTML PDF
1ZD1 SULT4A1 Q9BR01 Human Sulfortransferase SULT4A1 HTML PDF
1ZD8 AK3L1 Q9UIJ7 Structure of human adenylate kinase 3 like 1 HTML PDF
1ZD9 ARL10B Q96BM9 Structure of human ADP-ribosylation factor-like 10B HTML PDF
1ZDN E2-EPF5 Q16763 Ubiquitin-conjugating enzyme E2S HTML PDF
1ZIV CAPN9 O14815 Catalytic Domain of Human Calpain-9 HTML PDF
1ZJH PKM2 P14618 Structure of human muscle pyruvate kinase (PKM2) HTML PDF
1ZKC PPIL2 Q13356 Crystal Structure of the cyclophiln_RING domain of human peptidylprolyl isomerase (cyclophilin)-like 2 isoform b HTML PDF
1ZKH SF3A1 Q15459 Solution structure of a human ubiquitin-like domain in SF3A1 HTML PDF
1ZNQ GAPDH P04406 Crystal Structure of Human Liver GAPDH HTML PDF
1ZO2 Cp-NTF2 Q5CQI4 Structure of nuclear transport factor 2 (Ntf2) from Cryptosporidium parvum HTML PDF
1ZQ9 HSA9761 Q9UNQ2 Crystal structure of human Dimethyladenosine transferase HTML PDF
1ZRH HS3ST1 O14792 Crystal structure of Human heparan sulfate glucosamine 3-O-sulfotransferase 1 in complex with PAP HTML PDF
1ZS6 NME3 Q13232 structure of human nucleoside-diphosphate kinase 3 HTML PDF
1ZSV LTB4DH Q14914 Crystal structure of human NADP-dependent leukotriene B4 12-hydroxydehydrogenase HTML PDF
1ZSX KCNAB2 Q13303 Crystal Structure Of Human Potassium Channel Kv Beta-subunit (KCNAB2) HTML PDF
1ZSY CGI63 Q9BV79 The structure of human mitochondrial 2-enoyl thioester reductase (CGI-63) HTML PDF
1ZUO UBCi Q8WVN8 Structure of Human Ubiquitin-Conjugating Enzyme (UBCi) Involved in Embryo Attachment and Implantation HTML PDF
1ZV4 RGS17 Q9UGC6 Structure of the Regulator of G-Protein Signaling 17 (RGSZ2) HTML PDF
1ZW5 FDPS-Zoledronate P14324 X-ray structure of Farnesyl diphosphate synthase protein HTML PDF
1ZX0 (superseded by 3ORH) GAMT Q14353 Human guanidinoacetate N-methyltransferase with SAH HTML PDF
1ZX1 NQO2 P16083 Human quinone oxidoreductase 2 (NQO2) in complex with the cytostatic prodrug CB1954 HTML PDF
2A14 INMT O95050 Crystal Structure of Human Indolethylamine N-methyltransferase with SAH HTML PDF
2A1X PHYH O14832 Human phytanoyl-coa 2-hydroxylase in complex with iron and 2-oxoglutarate HTML PDF
2A22 Cp-VPS29 Q5CYJ7 Structure of Vacuolar Protein Sorting 29 from Cryptosporidium Parvum HTML PDF
2A2N PPWD1 Q96BP3 Crystal Structure of the peptidylprolyl isomerase domain of Human PPWD1 HTML PDF
2A3K PTPN7 P35236 Crystal Structure of the Human Protein Tyrosine Phosphatase, PTPN7 (HePTP, Hematopoietic Protein Tyrosine Phosphatase) HTML PDF
2A4A Py-DERA Q7RMC9 Deoxyribose-phosphate aldolase from P. yoelii HTML PDF
2A4D UEV1 Q13404 Structure of the human ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) HTML PDF
2A5J RAB2B Q8WUD1 Crystal Structure of Human RAB2B HTML PDF
2A72 RGS7 P49802 Structure of the regulator of G-protein signaling domain of RGS7 HTML PDF
2A7L FLJ11011 Q96B02 Structure of the human hypothetical ubiquitin-conjugating enzyme, LOC55284 HTML PDF
2A7V (superseded by 3OU5, 6DK3) SHMT2 P34897 Human Mitochondrial Serine Hydroxymethyltransferase HTML PDF
2A8B PTPRR Q15256 Crystal Structure of the Catalytic Domain of Human Tyrosine Phosphatase Receptor, Type R HTML PDF
2A98 ITPKC Q96DU7 Crystal structure of the catalytic domain of human inositol 1,4,5-trisphosphate 3-kinase C HTML PDF
2A9U USP08 P40818 Structure of the N-terminal domain of Human Ubiquitin carboxyl-terminal hydrolase 8 (USP8) HTML PDF
2AD1 SULT1C2 O75897 Human Sulfotransferase SULT1C2 HTML PDF
2AED (superseded by 4DRZ) RAB14 P61106 Crystal structure of human RAB14 HTML PDF
2AF0 RGS2 P41220 Structure of the Regulator of G-Protein Signaling Domain of RGS2 HTML PDF
2AG5 DHRS6 Q9BUT1 Crystal Structure of Human DHRS6 HTML PDF
2AHS PTPRB P23467 Crystal Structure of the Catalytic Domain of Human Tyrosine Receptor Phosphatase Beta HTML PDF
2AIF Cp-NHP2 Q7YYQ3 Crystal Structure of High Mobility Like Protein, NHP2, putative from Cryptosporidium parvum HTML PDF
2AJP PDXK O00764 Crystal structure of a human pyridoxal kinase HTML PDF
2AL7 ARL10C Q9NVJ2 Structure Of Human ADP-Ribosylation Factor-Like 10C HTML PDF
2AMX Py-ADA Q7RMV2 Crystal structure of Plasmodium Yoelii Adenosine deaminase (PY02076) HTML PDF
2AQW Py-OMPDC Q7RPE4 Structure of putative orotidine-monophosphate-decarboxylase from Plasmodium yoelii (PY01515) HTML PDF
2AR7 AK4 P27144 Crystal structure of human adenylate kinase 4, AK4 HTML PDF
2ARY CAPN1 P07384 Catalytic domain of Human Calpain-1 HTML PDF
2ATV RERG Q96A58 The crystal structure of human RERG in the GDP bound state HTML PDF
2AV4 Py-U5-15kD Q7R866 Crystal structure of Plasmodium yoelii thioredoxin-like protein 4A (DIM1) HTML PDF
2AVD COMTD1 Q86VU5 Crystal Structure of Human Catechol-O-methyltransferase domain containing 1 HTML PDF
2AW5 ME1 P48163 Crystal structure of a human malic enzyme HTML PDF
2AWF UBE2G1 P62253 Structure of human Ubiquitin-conjugating enzyme E2 G1 HTML PDF
2AWG FKBP8 Q14318 Structure of the PPIase domain of the Human FK506-binding protein 8 HTML PDF
2AWP Pk-SOD1 D0VWV6 Crystal structure of Plasmodium knowlesi structure of Iron Super-Oxide Dismutase HTML PDF
2AX4 PAPSS2 O95340 Crystal structure of the kinase domain of human 3'-phosphoadenosine 5'-phosphosulphate synthetase 2 HTML PDF
2AYV Tg-UBC (TgTwinScan_2218) Crystal structure of a putative ubiquitin-conjugating enzyme E2 from Toxoplasma gondii HTML PDF
2B05 YWHAG P61981 Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide HTML PDF
2B0O UPLC1 Q8TDY4 Crystal structure of UPLC1 GAP domain HTML PDF
2B0R Cp-CAP1 Q5CS32 Crystal Structure of Cyclase-Associated Protein from Cryptosporidium parvum HTML PDF
2B25 FLJ20628 Q9BVS5 Human putative tRNA(1-methyladenosine)methyltransferase HTML PDF
2B49 PTPN3 P26045 Crystal Structure of the Catalytic Domain of Protein Tyrosine Phosphatase, non-receptor Type 3 HTML PDF
2B4Y SIRT5 Q9NXA8 Crystal Structure of Human Sirtuin homolog 5 HTML PDF
2B69 UXS1 Q8NBZ7 Crystal Structure of Human UDP-glucoronic acid decarboxylase HTML PDF
2B6H ARF5 P84085 Structure of human ADP-ribosylation factor 5 HTML PDF
2B71 Py-PPI (PY00693) Q7RRM6 Plasmodium yoelii cyclophilin-like protein HTML PDF
2B9E NSUN5 Q96P11 Human NSUN5 protein HTML PDF
2BBJ CorA Q9WZ31 Crystal structure of the CorA Mg2+ transporter HTML PDF
2BBW AK4-gp5G P27144 Crystal structure of human adenylate kinase 4 (AK4) in complex with diguanosine pentaphosphate HTML PDF
2BDD Py-ACPS Q7RB63 Crystal Structure of Holo-ACP-synthase from Plasmodium yoelii HTML PDF
2BEL 11BHSD1 P28845 Structure of human 11-beta-hydroxysteroid dehydrogenase in complex with NADP and carbenoxolone HTML PDF
2BIJ PTPN5 P54829 Crystal structure of the human protein tyrosine phosphatase PTPN5 (STEP, striatum enriched enriched Phosphatase) HTML PDF
2BIK PIM1-phos P11309 Human Pim1 phosphorylated on Ser261 HTML PDF
2BIL PIM1-pep P11309 The human protein kinase Pim1 in complex with its consensus peptide Pimtide HTML PDF
2BLE GMPR P36959 Structure of human guanosine monophosphate reductase GMPR1 in complex with GMP HTML PDF
2BMJ CENTG1 Q99490 GTPase like domain of Centaurin Gamma 1 (Human) HTML PDF
2BP1 AKR7A2 O43488 Structure of the aflatoxin aldehyde reductase in complex with NADPH HTML PDF
2BQ0 YWHAB P31946 14-3-3 Protein Beta (Human) HTML PDF
2BR9 YWHAE P62258 14-3-3 Protein Epsilon (Human) Complexed to Peptide HTML PDF
2BT2 RGS16 O15492 Structure of the regulator of G-protein signaling 16 HTML PDF
2BTP YWHAQ P27348 14-3-3 Protein Theta (Human) Complexed to Peptide HTML PDF
2BUJ STK16 O75716 Crystal structure of the human Serine-threonine Kinase 16 in complex with staurosporine HTML PDF
2BV1 RGS1 Q08116 Regulator of G-protein Signalling 1 (Human) HTML PDF
2BV5 PTPN5 - follow-up P54829 CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5 AT 1.8A RESOLUTION HTML PDF
2BVA PAK4 O96013 Crystal structure of the human P21-activated kinase 4 HTML PDF
2BW0 FTHFD O75891 Crystal Structure of the hydrolase domain of Human 10-Formyltetrahydrofolate 2 dehydrogenase HTML PDF
2BWG GMPR - follow-up P36959 Structure of human guanosine monophosphate reductase GMPR1 in complex with GMP HTML PDF
2BWJ AK5 Q9Y6K8 Structure of adenylate kinase 5 HTML PDF
2BYD AASDHPPT Q9NRN7 Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase HTML PDF
2BYG DLG2 Q15700 2nd PDZ Domain of Discs Large Homologue 2 HTML PDF
2BZG TPMT P51580 Crystal structure of thiopurine S-methyltransferase. HTML PDF
2BZH PIM1-OrgMet-Ru1 P11309 CRYSTAL STRUCTURE OF THE HUMAN PIM1 IN COMPLEX WITH A RUTHENIUM ORGANOMETALLIC LIGAND RU1 HTML PDF
2BZI PIM1-OrgMet-Ru2 P11309 CRYSTAL STRUCTURE OF THE HUMAN PIM1 IN COMPLEX WITH A RUTHENIUM ORGANOMETALLIC LIGAND RU2 HTML PDF
2BZJ PIM1-OrgMet-Ru3 P11309 CRYSTAL STRUCTURE OF THE HUMAN PIM1 IN COMPLEX WITH A RUTHENIUM ORGANOMETALLIC LIGAND RU3 HTML PDF
2BZK PIM1-AMPPNP P11309 CRYSTAL STRUCTURE OF THE HUMAN PIM1 IN COMPLEX WITH AMPPNP AND PIMTIDE HTML PDF
2BZL PTPN14 Q15678 CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE N14 AT 1. 65 A RESOLUTION HTML PDF
2BZN GMPR2 Q9P2T1 Crystal structure of human guanosine monophosphate reductase 2 GMPR2 in complex with IMP HTML PDF
2C0C MGC45594 Q8N4Q0 Structure of the MGC45594 gene product HTML PDF
2C23 YWHAB-ExoS P31946, Q51451 14-3-3 Protein Beta (Human) in complex with exoenzyme S peptide HTML PDF
2C2H RAC3 P60763 CRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH GDP HTML PDF
2C2N MT Q8IVS2 Structure of human mitochondrial malonyltransferase HTML PDF
2C30 PAK6 Q9NQU5 Crystal Structure Of The Human P21-Activated Kinase 6 HTML PDF
2C3I PIM1-imid P11309 CRYSTAL STRUCTURE OF HUMAN PIM1 IN COMPLEX WITH IMIDAZOPYRIDAZIN I HTML PDF
2C43 AASDHPPT-coa Q9NRN7 STRUCTURE OF AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE- PHOSPHOPANTETHEINYL TRANSFERASE IN COMPLEX WITH COENZYME A HTML PDF
2C46 RNGTT O60942 CRYSTAL STRUCTURE OF THE HUMAN RNA guanylyltransferase and 5'- phosphatase HTML PDF
2C47 CSNK1G2 P78368 Structure of casein kinase 1 gamma 2 HTML PDF
2C4K PRPSAP1 Q14558 Crystal structure of human phosphoribosylpyrophosphate synthetase- associated protein 39 (PAP39) HTML PDF
2C5M (superseded by 2VO1) CTPS P17812 CRYSTAL STRUCTURE OF THE SYNTHETASE DOMAIN OF HUMAN CTP SYNTHETASE HTML PDF
2C60 MAP3K3 Q99759 crystal structure of human mitogen-activated protein kinase kinase kinase 3 isoform 2 phox domain at 1.25 A resolution HTML PDF
2C63 YWHAH Q04917 14-3-3 Protein Eta (Human) Complexed to Peptide HTML PDF
2C6Q GMPR2-NADPH/IMP Q9P2T1 Crystal structure of human guanosine monophosphate reductase 2 GMPR2 in complex with IMP and NADPH HTML PDF
2C74 YWHAH + SEP CIT Q04917 14-3-3 Protein Eta (Human) Complexed to Peptide HTML PDF
2C7S PTPRK Q15262 Crystal structure of human protein tyrosine phosphatase kappa at 1.95A resolution HTML PDF
2C95 AK1 - follow-up P00568 Structure of adenylate kinase 1 in complex with P1,P4-di(adenosine) tetraphosphate HTML PDF
2C9H FLJ20604 Q9NWU1 Structure of mitochondrial beta-ketoacyl synthase HTML PDF
2C9W SOCS2-ElonginC-ElonginB O14508, Q15370, Q15369 CRYSTAL STRUCTURE OF SOCS-2 IN COMPLEX WITH ELONGIN-B AND ELONGIN-C AT 1.9A RESOLUTION HTML PDF
2C9Y AK2 P54819 Structure of human adenylate kinase 2 HTML PDF
2CAR ITPA Q9BY32 Crystal Structure Of Human Inosine Triphosphatase HTML PDF
2CDZ PAK4+cdk1 inhibitor O96013 CRYSTAL STRUCTURE OF THE HUMAN P21-ACTIVATED KINASE 4 IN COMPLEX WITH CGP74514A HTML PDF
2CFI FTHFD + 6-formylpteridin O75891 The hydrolase domain of human 10-FTHFD in complex with 6- formyltetrahydropterin HTML PDF
2CFV PTPRJ Q12913 Crystal structure of human protein tyrosine phosphatase receptor type J HTML PDF
2CFY TXNRD1 Q16881 Crystal structure of human thioredoxin reductase 1 HTML PDF
2CG5 AASDHPPT + ACP Q9NRN7, P49327 Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase in complex with cytosolic acyl carrier protein and coenzyme A HTML PDF
2CHL CSNK1G3 Q9Y6M4 Structure of casein kinase 1 gamma 3 HTML PDF
2CJZ PTPN5 + fragment of the ERK2 activation loop P54829 crystal structure of the c472s mutant of human protein tyrosine phosphatase ptpn5 (step, striatum enriched phosphatase) in complex with phosphotyrosine HTML PDF
2CL3 CPSF5 O43809 Crystal structure of human Cleavage and Polyadenylation Specificity Factor 5 (CPSF5) HTML PDF
2CLP AKR7A3 O95154 Crystal structure of human aflatoxin B1 aldehyde reductase member 3 HTML PDF
2CLQ MAP3K5 Q99683 Structure of mitogen-activated protein kinase kinase kinase 5 HTML PDF
2CLS RND1 Q92730 The crystal structure of the human RND1 GTPase in the active GTP bound state HTML PDF
2CMW CSNK1G1 Q9HCP0 Structure of Human Casein kinase 1 gamma-1 in complex with 2-(2- Hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine HTML PDF
2CN1 NT5C3 Q9H0P0 Crystal structure of Human Cytosolic 5'-Nucleotidase III (NT5C3) HTML PDF
2DFD MDH2 P40926 Crystal Structure of Human Malate Dehydrogenase Type 2 HTML PDF
2ERX DIRAS2 Q96HU8 Crystal Structure of DiRas2 in Complex With GDP and Inorganic Phosphate HTML PDF
2ERY RRAS2 P62070 The crystal structure of the Ras related protein RRas2 (RRAS2) in the GDP bound state HTML PDF
2ES0 RGS6 P49758 Structure of the regulator of G-protein signaling domain of RGS6 HTML PDF
2ESL PPIC P45877 Human Cyclophilin C in Complex with Cyclosporin A HTML PDF
2ETG (superseded by 3BFX) SULT1C1 O00338 Crystal structure of human sulfotransferase SULT1C1 in complex with PAP HTML PDF
2EU9 CLK3 P49761 Crystal Structure of CLK3 HTML PDF
2EW1 RAB30 Q15771 Crystal Structure of Rab30 in complex with a GTP analogue HTML PDF
2EX4 AD-003 Q9BV86 Crystal Structure of Human methyltransferase AD-003 in complex with S-adenosyl-L-homocysteine HTML PDF
2EXE CLK3 - phosphorylated P49761 Crystal structure of the phosphorylated CLK3 HTML PDF
2F15 AMPKB2 O43741 Glycogen-Binding Domain Of The Amp-Activated Protein Kinase beta2 Subunit HTML PDF
2F2S ACAT1 P24752 Human mitochondrial acetoacetyl-CoA thiolase HTML PDF
2F4W UBE2J2 Q8N2K1 Human ubiquitin-conjugating enzyme E2 J2 HTML PDF
2F4Z Tg-E2-25 Toxoplasma gondii ubiquitin conjugating enzyme TgTwinScan_2721- E2 domain HTML PDF
2F57 PAK5 Q9P286 Crystal Structure Of The Human P21-Activated Kinase 5 HTML PDF
2F5Y RGS3 P49796 Crystal Structure of the PDZ Domain from Human RGS-3 HTML PDF
2F6I Pf-ClpP O97252 Crystal structure of the ClpP protease catalytic domain from Plasmodium falciparum HTML PDF
2F6Q PECI O75521 The crystal structure of human peroxisomal delta3, delta2 enoyl CoA isomerase (PECI) HTML PDF
2F73 FABP1 P07148 Crystal structure of human fatty acid binding protein 1 (FABP1) HTML PDF
2F7S RAB27B O00194 The crystal structure of human Rab27b bound to GDP HTML PDF
2F8A GPX1 P07203 Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1 HTML PDF
2FAZ UHRF1 Q96T88 Ubiquitin-Like Domain of Human Nuclear Zinc Finger Protein NP95 HTML PDF
2FBM CDY1 Q9Y6F8 Acetyltransferase domain of CDY1 HTML PDF
2FBN Pf-FKBP-TPR Q8I4V8 Plasmodium falciparum putative FK506-binding protein PFL2275c, C-terminal TPR-containing domain HTML PDF
2FCF MPDZ O75970 The crystal structure of the 7th PDZ domain of MPDZ (MUPP-1) HTML PDF
2FDS Pb-OMPDC Q4Z4C3 Crystal Structure of Plasmodium Berghei Orotidine 5'-monophosphate Decarboxylase (ortholog of Plasmodium falciparum PF10_0225) HTML PDF
2FE5 DLG3 Q92796 The Crystal Structure of the Second PDZ Domain of Human DLG3 HTML PDF
2FFC Pv-OMPDC-UMP Crystal Structure of Plasmodium Vivax Orotidine-Monophosphate-Decarboxyl UMP Bound HTML PDF
2FG5 RAB31 Q13636 Crystal structure of human RAB31 in complex with a GTP analogue HTML PDF
2FIM TULP1 O00294 Structure of the C-terminal domain of Human Tubby-like protein 1 HTML PDF
2FK9 PRKCH P24723 Human protein kinase C, eta HTML PDF
2FLS GLRX2 Q9NS18 Crystal structure of Human Glutaredoxin 2 complexed with glutathione HTML PDF
2FN4 RRAS P10301 The crystal structure of human Ras-related protein, RRAS, in the GDP-bound state HTML PDF
2FNE MPDZ (13th domain) O75970 The crystal structure of the 13th PDZ domain of MPDZ HTML PDF
2FO3 Pv-UBC A5K893 Plasmodium vivax ubiquitin conjugating enzyme E2 HTML PDF
2FOL RAB1A P62820 Crystal structure of human RAB1A in complex with GDP HTML PDF
2FU0 Pf-PPWD1 Q8I402 Plasmodium falciparum cyclophilin PFE0505w putative cyclosporin-binding domain HTML PDF
2FV7 RBKS Q9H477 Crystal structure of human ribokinase HTML PDF
2FV8 RHOB P62745 The crystal structure of RhoB in the GDP-bound state HTML PDF
2FVL AKR1C4 P17516 Crystal structure of human 3-alpha hydroxysteroid/dihydrodiol dehydrogenase (AKR1C4) complexed with NADP+ HTML PDF
2FVV NUDT3 O95989 Human Diphosphoinositol polyphosphate phosphohydrolase 1 HTML PDF
2FVZ IMPA2 O14732 Human Inositol Monophosphosphatase 2 HTML PDF
2FW2 CDY Q9Y6F7 Catalytic domain of CDY HTML PDF
2FWK (superseded by 3PGG) Cp-LSm5 Q5CXX3 Crystal structure of cryptosporidium parvum u6 snrna-associated sm-like protein lsm5 HTML PDF
2FXF SAT P21673 Human spermidine/spermine N1-acetyltransferase HTML PDF
2FYT PRMT3 O60678 Human HMT1 hnRNP methyltransferase-like 3 (S. cerevisiae) protein HTML PDF
2FZP NRDP1 Q9H4P4 Crystal structure of the USP8 interaction domain of human NRDP1 HTML PDF
2G0N RAC3+Cl P60763 The Crystal Structure of the Human RAC3 in complex with GDP and Chloride HTML PDF
2G1L KIF1C-FHA O43896 Crystal structure of the FHA domain of human kinesin family member C HTML PDF
2G3Y GEM P55040 Crystal structure of the human small GTPase GEM HTML PDF
2G62 PPP2R4 Q15257 Crystal structure of human PTPA HTML PDF
2G6B RAB26 Q9ULW5 Crystal structure of human RAB26 in complex with a GTP analogue HTML PDF
2G76 PHGDH O43175 Crystal structure of human 3-phosphoglycerate dehydrogenase HTML PDF
2G7R MALT1-DD Q9UDY8 X-ray structure of the death domain of the human mucosa associated lymphoid tissue lymphoma translocation protein 1 HTML PDF
2G9N DDX2A/eIF4A P60842 Structure of the DEAD domain of Human eukaryotic initiation factor 4A, eIF4A HTML PDF
2GAO SARA1 Q9NR31 Crystal Structure of Human SAR1a in Complex With GDP HTML PDF
2GBD (superseded by 2QW4) NR4A1 P22736 Human NR4A1 ligand-binding domain HTML PDF
2GDZ HPGD P15428 Crystal structure of 15-hydroxyprostaglandin dehydrogenase type1, complexed with NAD+ HTML PDF
2GF0 DIRAS O95057 The crystal structure of the human DiRas1 GTPase in the inactive GDP bound state HTML PDF
2GF2 HIBADH P31937 Crystal structure of human hydroxyisobutyrate dehydrogenase HTML PDF
2GF9 RAB3D O95716 Crystal structure of human RAB3D in complex with GDP HTML PDF
2GFO USP08 - catalytic domain P40818 Structure of the Catalytic Domain of Human Ubiquitin Carboxyl-terminal Hydrolase 8 HTML PDF
2GHI Py-MDR2-NBD Q7RBT4 Crystal Structure of Plasmodium yoelii Multidrug Resistance Protein 2 HTML PDF
2GIV MYST1 Q9H7Z6 Human MYST histone acetyltransferase 1 HTML PDF
2GJS RRAD P55042 The crystal structure of human RRAD in complex with GDP HTML PDF
2GJT PTPRO Q16827 Crystal structure of the human receptor phosphatase PTPRO HTML PDF
2GK9 PIP5K2C Q8TBX8 Human Phosphatidylinositol-4-phosphate 5-kinase, type II, gamma HTML PDF
2GL6 (superseded by 4Z9M) CKMT2 P17540 Crystal structure of human sarcomeric mitochondrial creatine kinase HTML PDF
2GL8 RXRG P48443 Human Retinoic acid receptor RXR-gamma ligand-binding domain HTML PDF
2GNQ WDR5 P61964 Structure of wdr5 HTML PDF
2GRY KIF2 O00139 Crystal structure of the human KIF2 motor domain in complex with ADP HTML PDF
2GS3 GPX4 P36969 Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 4(GPX4) HTML PDF
2GSE DPYSL2 Q16555 Crystal Structure of Human Dihydropyrimidinease-like 2 HTML PDF
2GSF EPHA3 P29320 The Human Epha3 Receptor Tyrosine Kinase and Juxtamembrane Region HTML PDF
2GTP RGS1 + Galphai1 P63096, Q08116 Crystal structure of the heterodimeric complex of human RGS1 and activated Gi alpha 1 HTML PDF
2GTR CDYL Q9Y232 Human chromodomain Y-like protein HTML PDF
2GUU Pv-OMPDC-6-aza-UMP crystal structure of Plasmodium vivax orotidine 5-monophosphate decarboxylase with 6-aza-UMP bound HTML PDF
2GW2 PPIG Q13427 Crystal structure of the peptidyl-prolyl isomerase domain of human cyclophilin G HTML PDF
2GWF NRDP1 + USP08 P40818, Q9H4P4 Structure of a USP8-NRDP1 complex HTML PDF
2GWH SULT1C2+PAP+PCP O75897 Human Sulfotranferase SULT1C2 in complex with PAP and pentachlorophenol HTML PDF
2GZV PRKCABP Q9NRD5 The cystal structure of the PDZ domain of human PICK1 HTML PDF
2H00 METT10D Q86W50 Human methyltransferase 10 domain containing protein HTML PDF
2H01 Py-2-Cys-Prx Q7RSE5 PY00414- Plasmodium yoelii thioredoxin peroxidase I HTML PDF
2H17 ARL5:Q15-L176 Q9Y689 Structure of human ADP-ribosylation factor-like 5 (ARL5) HTML PDF
2H1R Pf-KsgA Q8ILT8 Crystal structure of a dimethyladenosine transferase from Plasmodium falciparum HTML PDF
2H4U THEM2 Q9NPJ3 Crystal Structure of Human Thioesterase Superfamily Member 2 HTML PDF
2H4V PTPRG P23470 Crystal Structure of the Human Tyrosine Receptor Phosphatase Gamma HTML PDF
2H57 ARL6 Q9H0F7 Crystal structure of human ADP-ribosylation factor-like 6 HTML PDF
2H58 (superseded by 5WDE) KIFC3 Q9BVG8 Crystal structure of the KIFC3 motor domain in complex with ADP HTML PDF
2H5G PYCS P54886 Crystal structure of human pyrroline-5-carboxylate synthetase HTML PDF
2H63 BLVRA P53004 Crystal Structure of Human Biliverdin Reductase A HTML PDF
2H66 Pv-2cys-Prx A5K421 The Crystal Structure of Plasmodium Vivax 2-Cys peroxiredoxin HTML PDF
2H6D AMPKA2 P54646 Protein Kinase Domain of the Human 5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK alpha-2 chain) HTML PDF
2H8K SULT1C3 Q6IMI6 Human Sulfotranferase SULT1C3 in complex with PAP HTML PDF
2H9L WDR5-Histone H3 P61964 WDR5delta23 HTML PDF
2H9M WDR5-Histone H3 P61964, Q6P823 WDR5 in complex with unmodified H3K4 peptide HTML PDF
2H9N WDR5-Histone H3 P61964, Q6P823 WDR5 in complex with monomethylated H3K4 peptide HTML PDF
2H9O (superseded by 2O9K) WDR5-Histone H3 P61964 WDR5 in Complex with Dimethylated H3K4 Peptide HTML PDF
2H9P WDR5-Histone 3 P61964, Q6P823 WDR5 in complex with trimethylated H3K4 peptide HTML PDF
2HA8 TARBP1 Q13395 Methyltransferase Domain of Human TAR (HIV-1) RNA binding protein 1 HTML PDF
2HDY (superseded by 3GZC) SCLY Q96I15 Structure of human selenocysteine lyase HTML PDF
2HE2 DLG2A (3rd domain) Q15700 Crystal structure of the 3rd PDZ domain of human discs large homologue 2, DLG2 HTML PDF
2HE3 GPX2 P18283 Crystal structure of the selenocysteine to cysteine mutant of human glutathionine peroxidase 2 (GPX2) HTML PDF
2HE4 NHERF-2 (2nd PDZ domain) Q15599 The crystal structure of the second PDZ domain of human NHERF-2 (SLC9A3R2) interacting with a mode 1 PDZ binding motif HTML PDF
2HE7 EPB41L3 Q9Y2J2 FERM domain of EPB41L3 (DAL-1) HTML PDF
2HE9 NKTR P30414 Structure of the peptidylprolyl isomerase domain of the human NK-tumour recognition protein HTML PDF
2HEH KIF2C Q99661 Crystal Structure of the KIF2C motor domain HTML PDF
2HEI RAB5B P61020 Crystal structure of human RAB5B in complex with GDP HTML PDF
2HER (superseded by 2Q58) Cp-PPPPS-Zoledronate Q5CR09 Cryptosporidium parvum putative polyprenyl pyrophosphate synthase (cgd4_2550) in complex with zoledronate HTML PDF
2HJR Cp-MDH Q5CYZ3 Crystal Structure of Cryptosporidium parvum malate dehydrogenase HTML PDF
2HLZ KHK P50053 Crystal Structure of human ketohexokinase HTML PDF
2HQ6 SDCCAG10 Q6UX04 Structure of the Cyclophilin_CeCYP16-Like Domain of the Serologically Defined Colon Cancer Antigen 10 from Homo Sapiens HTML PDF
2HRB CBR3 O75828 Crystal Structure of human Carbonyl Reductase 3, complexed with NADP+ HTML PDF
2HT9 GLRX2 + FeS Q9NS18 The structure of dimeric human glutaredoxin 2 HTML PDF
2HTE Pf-SRM Q8II73 The crystal structure of spermidine synthase from p. falciparum in complex with 5'-methylthioadenosine HTML PDF
2HUP RAB43 Q86YS6 Crystal structure of human RAB43 in complex with GDP HTML PDF
2HUZ GNPNAT1 Q96EK6 Crystal structure of GNPNAT1 HTML PDF
2HVG Pv-ASL A5KBL5 Crystal Structure of Adenylosuccinate Lyase from Plasmodium Vivax HTML PDF
2HW4 PHPT1 Q9NRX4 Crystal structure of human phosphohistidine phosphatase HTML PDF
2HW5 ECHS1 P30084 The crystal structure of human enoyl-coenzyme A (CoA) hydratase short chain 1, ECHS1 HTML PDF
2I1N DLG3 (1st PDZ domain) Q92796 Crystal structure of the 1st PDZ domain of Human DLG3 HTML PDF
2I3Y GPX5 O75715 Crystal structure of human glutathione peroxidase 5 HTML PDF
2I4I DDX3X O00571 Crystal Structure of human DEAD-box RNA helicase DDX3X HTML PDF
2I59 RGS10 O43665 Solution structure of RGS10 HTML PDF
2I62 mNNMT O55239 Mouse Nicotinamide N-methyltransferase HTML PDF
2I6L (superseded by 7AQB) MAPK6 Q16659 Crystal structure of human mitogen activated protein kinase 6 (MAPK6) HTML PDF
2I6T UEV3 Q8IX04 Orthorhombic Structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A HTML PDF
2I75 PTPN4 P29074 Crystal Structure of Human Protein Tyrosine Phosphatase N4 (PTPN4) HTML PDF
2I7A CAPN13 Q6MZZ7 Domain IV of Human Calpain 13 HTML PDF
2I7N PANK1 Q8TE04 Crystal structure of human PANK1 alpha: the catalytic core domain in complex with AcCoA HTML PDF
2I7P PANK3 Q9H999 Crystal structure of human PANK3 in complex with AcCoA HTML PDF
2I7Q CHKA P35790 Crystal structure of Human Choline Kinase A HTML PDF
2I81 Pv-2cys-Prx A5K421 Crystal Structure of Plasmodium vivax 2-Cys Peroxiredoxin, Reduced HTML PDF
2I9P HIBADH + cofactor P31937 Crystal structure of human hydroxyisobutyrate dehydrogenase complexed with NAD+ HTML PDF
2IBI USP2 O75604, P0CG48 Covalent Ubiquitin-USP2 Complex HTML PDF
2IBN ALDRL6 Q9UGB7 Crystal structure of Human myo-Inositol Oxygenase (MIOX) HTML PDF
2IC5 RAC3 in complex with GPPnhP P60763 Crystal structure of human RAC3 grown in the presence of Gpp(NH)p. HTML PDF
2IG7 CHKB Q9Y259 Crystal structure of Human Choline Kinase B HTML PDF
2IGQ EHMT1 Q9H9B1 Human euchromatic histone methyltransferase 1 HTML PDF
2IHC BACH1 O14867 Crystal structure of the bric-a-brac (BTB) domain of human BACH1 HTML PDF
2IHD RGS8 P57771 Crystal structure of Human Regulator of G-protein signaling 8, RGS8 HTML PDF
2IHI (superseded by 3MAV) PvGGPPS A5K4U6 Crystal structure of Plasmodium vivax putative farnesyl pyrophosphate synthase (Pv092040) HTML PDF
2IIK ACAA1 P09110 Crystal Structure of human peroxisomal acetyl-CoA acyl transferase 1 (ACAA1) HTML PDF
2IIP NNMT P40261 Human Nicotinamide N-methyltransferase HTML PDF
2IJA NAT1 P18440 Human N-acetyltransferase 1 F125S mutant HTML PDF
2IJP (superseded by 3EFZ) Cp-YWHAZ Q5CSF3 Crystal Structure of a 14-3-3 protein from cryptosporidium parvum (cgd1_2980) HTML PDF
2IK8 RGS16 + Galpha1 P63096, O15492 Crystal structure of the heterodimeric complex of human RGS16 and activated Gi alpha 1 HTML PDF
2IL1 LOC201475 Q6IQ22 Crystal structure of a predicted human GTPase in complex with GDP HTML PDF
2IPX FBL P22087 Human Fibrillarin HTML PDF
2IQJ SMAP1L Q8WU79 Crystal structure of the GAP domain of SMAP1L (LOC64744) stromal membrane-associated protein 1-like HTML PDF
2IVX CCNT2 O60583 Crystal structure of human cyclin T2 at 1.8 A resolution HTML PDF
2IWI PIM2 Q9P1W9 CRYSTAL STRUCTURE OF THE HUMAN PIM2 IN COMPLEX WITH A RUTHENIUM ORGANOMETALLIC LIGAND RU1 HTML PDF
2IWN MPDZ (3rd domain) O75970 3rd PDZ domain of Multiple PDZ Domain Protein MPDZ HTML PDF
2IWO MPDZ (12th domain) O75970 12th PDZ domain of Multiple PDZ Domain Protein MPDZ HTML PDF
2IWP MPDZ (12th domain), alt. crystal form O75970 12th PDZ domain of Multiple PDZ Domain Protein MPDZ HTML PDF
2IWQ MPDZ (7th domain), alt. crystal form O75970 7th PDZ domain of Multiple PDZ Domain Protein MPDZ HTML PDF
2IWR CENTG1, alt. crystal form Q99490 Gtpase Like Domain Of Centaurin Gamma 1 (Human) HTML PDF
2IZR CSNK1G3 + K00576 Q9Y6M4 Structure of casein kinase gamma 3 in complex with inhibitor HTML PDF
2IZS CSNK1G3 + K00577 Q9Y6M4 Structure of casein kinase gamma 3 in complex with inhibitor HTML PDF
2IZT CSNK1G3 + CGP74514A Q9Y6M4 Structure of casein kinase gamma 3 in complex with inhibitor HTML PDF
2IZU CSNK1G3 + K00227 Q9Y6M4 Structure of casein kinase gamma 3 in complex with inhibitor HTML PDF
2IZV SOCS4-Elongin B/C Q8WXH5, Q15370, Q15369 CRYSTAL STRUCTURE OF SOCS-4 IN COMPLEX WITH ELONGIN-B AND ELONGIN-C AT 2.55A RESOLUTION HTML PDF
2IZZ PYCR P32322 Crystal structure of human pyrroline-5-carboxylate reductase HTML PDF
2J0I PAK4 O96013 CRYSTAL STRUCTURE OF THE HUMAN P21-ACTIVATED KINASE 4 HTML PDF
2J1L RHOD O00212 Crystal Structure of Human Rho-related GTP-binding protein RhoD HTML PDF
2J2C NT5C2 P49902 Crystal structure of Human Cytosolic 5'-Nucleotidase II (NT5C2, cN-II) HTML PDF
2J2I PIM1 in complex with LY333531 P11309 Crystal Structure of the humab PIM1 in complex with LY333531 HTML PDF
2J51 SLK Q9H2G2 Crystal structure of Human STE20-like kinase bound to 5-Amino-3-((4-(aminosulfonyl)phenyl)amino) -N-(2,6-difluorophenyl)-1H-1,2,4-triazole- 1-carbothioamide HTML PDF
2J67 TLR10 Q9BXR5 The TIR domain of human Toll-Like Receptor 10 (TLR10) HTML PDF
2J6L ALDH7A1 P49419 Structure of aminoadipate-semialdehyde dehydrogenase HTML PDF
2J7T STK10 O94804 Crystal structure of human serine threonine kinase-10 bound to SU11274 HTML PDF
2J8Z TP53I3 Q53FA7 Crystal Structure of human P53 inducible oxidoreductase (TP53I3,PIG3) HTML PDF
2J90 DAPK3 O43293 Crystal structure of human ZIP kinase in complex with a tetracyclic pyridone inhibitor (Pyridone 6) HTML PDF
2J91 ADSL P30566 Crystal structure of Human Adenylosuccinate Lyase in complex with AMP HTML PDF
2JAK PPP2R5C Q13362 Human PP2A regulatory subunit B56g HTML PDF
2JAM CAMK1G Q96NX5 Crystal structure of human calmodulin-dependent protein kinase I G HTML PDF
2JAV NEK2 P51955 Human Kinase with pyrrole-indolinone ligand HTML PDF
2JBH PRTFDC1 Q9NRG1 Human phosphoribosyl transferase domain containing 1 HTML PDF
2JC6 CAMK1D Q8IU85 Crystal structure of human calmodulin-dependent protein kinase 1D HTML PDF
2JCN BAK1 Q16611 The crystal structure of BAK1 - a mitochondrial apoptosis regulator HTML PDF
2JEO UCK1 Q9HA47 Crystal structure of human uridine-cytidine kinase 1 HTML PDF
2JFD FAS P49327 Structure of the MAT domain of human FAS HTML PDF
2JFK FAS transferase domain + CoA P49327 Structure of the MAT domain of human FAS with malonyl-CoA HTML PDF
2JFL SLK di-phosphorylated + K00546 Q9H2G2 CRYSTAL STRUCTURE OF HUMAN STE20-LIKE KINASE (DIPHOSPHORYLATED FORM) BOUND TO 5- AMINO-3-((4-(AMINOSULFONYL)PHENYL)AMINO)-N-(2,6- DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE HTML PDF
2JFM SLK mono-phosphorylated Q9H2G2 CRYSTAL STRUCTURE OF HUMAN STE20-LIKE KINASE (UNLIGANDED FORM) HTML PDF
2JGY UMPS P11172 The crystal structure of human orotidine-5'-decarboxylase domain of human uridine monophosphate synthetase (UMPS) HTML PDF
2JI4 PRPSAP2 O60256 Human phosphoribosylpyrophosphate synthetase - associated protein 41 (PAP41) HTML PDF
2JIF ACADSB P45954 Structure of human short-branched chain acyl-CoA dehydrogenase (ACADSB) HTML PDF
2JII VRK3 Q8IV63 Structure of vaccinia related kinase 3 HTML PDF
2JIK SYNJ2BP P57105 Crystal structure of PDZ domain of Synaptojanin-2 binding protein HTML PDF
2JIL GRIP1 Q9Y3R0 Crystal structure of 2nd PDZ domain of glutamate receptor interacting protein-1 (GRIP1) HTML PDF
2JIN SYNJ2BP P57105 Crystal structure of PDZ domain of Synaptojanin-2 binding protein HTML PDF
2JIS CSAD Q9Y600 Human cysteine sulfinic acid decarboxylase (CSAD) in complex with PLP. HTML PDF
2JJD PTPRE P23469 Protein Tyrosine Phosphatase, Receptor Type, E isoform HTML PDF
2JK9 SPSB1 Q96BD6, Q96IZ0 The structure of splA-ryanodine receptor domain and SOCS box containing 1 in complex with a PAR-4 peptide HTML PDF
2JKU PCCA P05165 Crystal structure of the N-terminal region of the biotin acceptor domain of human propionyl-CoA carboxylase HTML PDF
2JKV PGD P52209 Structure of human Phosphogluconate Dehydrogenase in complex with NADPH at 2.53A HTML PDF
2JNU RGS14 O43566 Solution structure of the RGS domain of human RGS14 HTML PDF
2JP2 SPRED2 Q7Z698 Solution structure and resonance assignment of the N-terminal EVH1 domain from the human Spred2 protein (Sprouty-related protein with EVH1 domain isoform 2) HTML PDF
2JRZ JARID1C P41229 Solution structure of the Bright/ARID domain from the human JARID1C protein. HTML PDF
2JUF PARC Q8IWT3 NMR solution structure of PARC CPH Domain. NESG Target HR3443B/SGC-Toronto HTML PDF
2JXX NFATC2IP Q8NCF5 NMR solution structure of Ubiquitin-like domain of NFATC2IP. Northeast Structural Genomics Consortium target HR5627 HTML PDF
2K1B CBX7 O95931 Solution NMR structure of the chromo domain of the chromobox protein homolog 7 HTML PDF
2K28 CBX4 O00257 Solution NMR structure of the chromo domain of the chromobox protein homolog 4 HTML PDF
2KDB HERPUD2 Q9BSE4 Solution Structure of human ubiquitin-like domain of Herpud2_9_85, Northeast Structural Genomics Consortium (NESG) target HT53A HTML PDF
2KDN PFE0790c Q8I3V0 Solution structure of PFE0790c, a putative bolA-like protein from the protozoan parasite Plasmodium falciparum. HTML PDF
2KEO HERC2 O95714 Solution NMR structure of human protein HS00059, cytochrome-b5-like domain of the HERC2 E3 ligase. Northeast structural genomics consortium (NESG) target ht98a HTML PDF
2KFV FKBP3 Q00688 Structure of the amino-terminal domain of human FK506-binding protein 3 / Northeast Structural Genomics Consortium Target HT99A HTML PDF
2KLC UBQLN1 Q9UMX0 NMR solution structure of human ubiquitin-like domain of ubiquilin 1, Northeast Structural Genomics Consortium (NESG) target HT5A HTML PDF
2KVR USP7 Q93009 Solution NMR structure of human ubiquitin specific protease Usp7 UBL domain (residues 537-664). NESG target hr4395c/ SGC-Toronto HTML PDF
2L1I (superseded by 5K5F) HLTF Q14527 NMR structure of the HLTF HIRAN domain HTML PDF
2L2D OTUD7A Q8TE49 Solution NMR Structure of human UBA-like domain of OTUD7A_11_83, NESG target HT6304A/OCSP target OTUD7A_11_83/SGC-Toronto HTML PDF
2L76 NFATC2IP Q8NCF5 Solution NMR structure of human NFATC2IP ubiquitin-like domain, NFATC2IP_244_338, NESG target HT65A/OCSP target hs00387_244_338/SGC-toronto HTML PDF
2LC3 HECTD1 Q9ULT8 Solution NMR structure of a helical bundle domain from human E3 ligase HECTD1. Northeast structural genomics consortium (NESG) target HT6305A HTML PDF
2LFE HECW2 Q9P2P5 Solution NMR structure of N-terminal domain of human E3 ubiquitin-protein ligase HECW2, Northeast structural genomics consortium (NESG) target ht6306A HTML PDF
2LLK DMTF1 Q9Y222 Solution NMR structure of the N-terminal myb-like 1 domain of the human cyclin-D-binding transcription factor 1 (hDMP1), Northeast Structural Genomics Consortium (NESG) target ID hr8011a HTML PDF
2LLL LMNB2 Q03252 Solution NMR structure of C-terminal globular domain of human Lamin-B2, Northeast Structural Genomics Consortium target HR8546A HTML PDF
2LTP NCOR2 Q9Y618 Solution structure of the SANT2 domain of the human nuclear receptor corepressor 2 (NCoR2), Northeast Structural Genomics Consortium (NESG) target ID HR4636E HTML PDF
2LV9 MLL5 Q8IZD2 Solution NMR structure of the PHD domain of human MLL5, Northeast structural genomics consortium target HR6512A HTML PDF
2M2E DNAJC2 Q99543 Solution NMR structure of the SANT domain of human DNAJC2, Northeast structural genomics consortium target HR8254a HTML PDF
2NLK PTPRG P23470 Crystal structure of D1 and D2 catalytic domains of human Protein Tyrosine Phosphatase Gamma (D1+D2 PTPRG) HTML PDF
2NMP CTH P32929 Crystal structure of human Cystathionine gamma lyase HTML PDF
2NPM Cp-YWHAE Q5CUW0 crystal structure of Cryptosporidium parvum 14-3-3 protein in complex with peptide HTML PDF
2NPT MAP2K5 + MAP3K2 Q13163, Q9Y2U5 Crystal Structure of the complex of human mitogen activated protein kinase kinase 5 phox domain (MAP2K5-phox) with human mitogen activated protein kinase kinase kinase 2 phox domain (MAP3K2-phox) HTML PDF
2NQ3 ITCH Q96J02 Crystal structure of the C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase HTML PDF
2NQA CAPN8 A6NHC0, P17655 Catalytic Domain of Human Calpain 8 HTML PDF
2NR8 (superseded by 3NWN) KIF9 Q9HAQ2 Crystal structure of the human KIF9 motor domain in complex with ADP HTML PDF
2NSQ NEDD4L-C2 Q96PU5 Crystal structure of the C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein HTML PDF
2NVR (superseded by 3C0Y) HDAC7 Q8WUI4 Crystal structure of catalytic domain of human histone deacetylase HDAC7 HTML PDF
2NXB BRD3 domain 1 Q15059 Crystal structure of human Bromodomain containing protein 3 (BRD3) HTML PDF
2NYR SIRT5-Suramin Q9NXA8 Crystal Structure of Human Sirtuin Homolog 5 in Complex with Suramin HTML PDF
2NYU FTSJ2 Q9UI43 Crystal Structure of Human FtsJ homolog 2 (E.coli) protein in complex with S-adenosylmethionine HTML PDF
2NZ2 ASS P00966 Crystal structure of human argininosuccinate synthase in complex with aspartate and citrulline HTML PDF
2NZ6 PTPRJ CS mutant Q12913 Crystal structure of the PTPRJ inactivating mutant C1239S HTML PDF
2NZJ REM1 O75628 The crystal structure of REM1 in complex with GDP HTML PDF
2NZL HAO1 Q9UJM8 Crystal structure of human hydroxyacid oxidase 1 HTML PDF
2NZT HK2 P52789 Crystal structure of human hexokinase II HTML PDF
2O05 SRM+MTA P19623 Human spermidine synthase HTML PDF
2O06 SRM P19623 Human spermidine synthase HTML PDF
2O1Z Pv-RNR-R2 A5K1H0 Plasmodium vivax Ribonucleotide Reductase Subunit R2 (Pv086155) HTML PDF
2O23 HADH2 Q99714 The structure of wild-type human HADH2 (17beta-hydroxysteroid dehydrogenase type 10) bound to NAD+ at 1.2 A HTML PDF
2O25 UBCE2I-HIP2 P61086, P63279 Ubiquitin-Conjugating Enzyme E2-25 kDa Complexed With SUMO-1-Conjugating Enzyme UBC9 HTML PDF
2O28 GNPNAT1-CoA-GlcNAc6P Q96EK6 Crystal Structure of GNPNAT1 HTML PDF
2O2T MPDZA (1st domain) O75970 The crystal structure of the 1st PDZ domain of MPDZ HTML PDF
2O2V MAP2K5 + MAP3K3 Q13163, Q99759 Crystal Structure of the Complex of Human Mitogen Activated Protein Kinase Kinase 5 Phox Domain (MAP2K5-phox) with Human Mitogen Activated Protein Kinase Kinase Kinase 3 (MAP3K3B-phox) HTML PDF
2O52 RAB4B P61018 Crystal structure of human RAB4B in complex with GDP HTML PDF
2O8J EHMT2 Q96KQ7 Human euchromatic histone methyltransferase 2 HTML PDF
2O8P Cp-14-3-3 Q5CYG0 Crystal structure of a putative 14-3-3 protein from Cryptosporidium parvum, cgd7_2470 HTML PDF
2OB0 MAK3 Q9GZZ1 Human MAK3 homolog in complex with Acetyl-CoA HTML PDF
2OB4 CDC34 P49427 Human Ubiquitin-Conjugating Enzyme CDC34 HTML PDF
2OBV MAT1 Q00266 Crystal structure of the human S-adenosylmethionine synthetase 1 in complex with the product HTML PDF
2OC3 PTPN18 Q99952 Crystal Structure of the Catalytic Domain of Human Protein Tyrosine Phosphatase non-receptor Type 18 HTML PDF
2OCB RAB9B Q9NP90 Crystal structure of human RAB9B in complex with a GTP analogue HTML PDF
2OCS NHERF-2 (1st PDZ domain) Q15599 The crystal structure of the first PDZ domain of human NHERF-2 (SLC9A3R2) HTML PDF
2ODB CDC42 + PAK6 P60953, Q9NQU5 The crystal structure of human cdc42 in complex with the CRIB domain of human p21-activated kinase 6 (PAK6) HTML PDF
2ODE RGS8 + Galphai3 P08754, P57771 Crystal structure of the heterodimeric complex of human RGS8 and activated Gi alpha 3 HTML PDF
2ODT ITPK1 Q13572 Structure of human Inositol 1,3,4-trisphosphate 5/6-kinase HTML PDF
2OIL RAB25 P57735 Crystal structure of human RAB25 in complex with GDP HTML PDF
2OJD (superseded by 3C6G) CYP2R1 Q6VVX0 Crystal structure of CYP2R1 in complex with vitamin D3 HTML PDF
2OJW GS P15104 Crystal structure of human glutamine synthetase in complex with ADP and phosphate HTML PDF
2OLM HRB P52594 ArfGap domain of HIV-1 Rev binding protein HTML PDF
2OME CTBP2 P56545 Crystal structure of human CTBP2 dehydrogenase complexed with NAD(H) HTML PDF
2ONI NEDD4L Q96PU5 Catalytic Domain of the Human NEDD4-like E3 Ligase HTML PDF
2ONU Pf-UBE2H Q8IJ70 Plasmodium falciparum ubiquitin conjugating enzyme PF10_0330, putative homologue of human UBE2H HTML PDF
2OO1 BRD3 domain 2 Q15059 Crystal structure of the Bromo domain 2 of human Bromodomain containing protein 3 (BRD3) HTML PDF
2OOQ PTPRT O14522 Crystal Structure of the Human Receptor Phosphatase PTPRT HTML PDF
2OPG MPDZA (10th domain) O75970 The crystal structure of the 10th PDZ domain of MPDZ HTML PDF
2OPW PHYD1 Q5SRE7 Crystal structure of human phytanoyl-CoA dioxygenase PHYHD1 (apo) HTML PDF
2OQ6 JMJD2A + H3K9(me3) peptide O75164, P68431 Crystal structure of JMJD2A complexed with histone H3 peptide trimethylated at Lys9 HTML PDF
2OQ7 JMJD2A + Ni and N-oxalylglycine O75164 The crystal structure of JMJD2A complexed with Ni and N-oxalylglycine HTML PDF
2OQK Cp-eIF-1A Q5CVP1 Crystal structure of putative Cryptosporidium parvum translation initiation factor eIF-1A HTML PDF
2OS2 JMJD2A + H3K36(me3) peptide O75164 Crystal structure of JMJD2A complexed with histone H3 peptide trimethylated at Lys36 HTML PDF
2OSA CHN1 P15882 The Rho-GAP domain of human N-chimaerin HTML PDF
2OSS BRD4 domain 1 O60885 Crystal structure of the Bromo domain 1 in human Bromodomain Containing Protein 4 (BRD4) HTML PDF
2OT7 JMJD2A + H3K9(me1) peptide O75164, P68431 Crystal structure of JMJD2A complexed with histone H3 peptide monomethylated at Lys9 HTML PDF
2OU2 HTATIP Q92993 Acetyltransferase domain of Human HIV-1 Tat interacting protein, 60kDa, isoform 3 HTML PDF
2OUO BRD4 domain 2 O60885 Crystal Structure of the Bromo domain 2 in human Bromodomain Containing Protein 4 (BRD4) HTML PDF
2OV2 RAC3 + PAK4 P60763, O96013 The crystal structure of the human RAC3 in complex with the CRIB domain of human p21-activated kinase 4 (PAK4) HTML PDF
2OVJ RACGAP1 Q9H0H5 The crystal structure of the human Rac GTPase activating protein 1 (RACGAP1) MgcRacGAP. HTML PDF
2OWA Cp-ARFGAP Q5CRY1 Crystal structure of putative GTPase activating protein for ADP ribosylation factor from Cryptosporidium parvum (cgd5_1040) HTML PDF
2OWI RGS18 Q9NS28 Solution structure of the RGS domain from human RGS18 HTML PDF
2OX0 JMJD2A + H3K9(me2) peptide O75164, P68431 Crystal structure of JMJD2A complexed with histone H3 peptide dimethylated at Lys9 HTML PDF
2OXC DDX20 Q9UHI6 Human DEAD-box RNA helicase DDX20, DEAD domain in complex with ADP HTML PDF
2OXE LIPS P54317 Structure of the Human Pancreatic Lipase-related Protein 2 HTML PDF
2OZF NHERF-1(2nd PDZ domain) O14745 The crystal structure of the 2nd PDZ domain of the human NHERF-1 (SLC9A3R1) HTML PDF
2OZU MYST3 Q92794 Crystal structure of human MYST histone acetyltransferase 3 in complex with acetylcoenzyme A HTML PDF
2P02 MAT2A P31153 Crystal structure of the alpha subunit of human S-adenosylmethionine synthetase 2 HTML PDF
2P0A SYN3 O14994 The crystal structure of human synapsin III (SYN3) in complex with AMPPNP HTML PDF
2P0C MERTK Q12866 Catalytic Domain of the Proto-oncogene Tyrosine-protein Kinase MER HTML PDF
2P0E NRK1 Q9NWW6 Human nicotinamide riboside kinase 1 in complex with tiazofurin HTML PDF
2P0K SCMH1 Q96GD3 Crystal structure of SCMH1 HTML PDF
2P0R CAPN9 + leupeptin O14815 Structure of Human Calpain 9 in complex with Leupeptin HTML PDF
2P0W HAT1 O14929 Human histone acetyltransferase 1 (HAT1) HTML PDF
2P1I Py-RNR-R2 Q7RIF3 Plasmodium yoelii Ribonucleotide Reductase Subunit R2 (PY03671) HTML PDF
2P31 GPX7 Q96SL4 Crystal structure of human glutathione peroxidase 7 HTML PDF
2P57 ZNF289 Q8N6H7 GAP domain of ZNF289, an ID1-regulated zinc finger protein HTML PDF
2P5X ASMTL O95671 Crystal structure of Maf domain of human N-acetylserotonin O-methyltransferase-like protein HTML PDF
2P65 Pv-ClpB-NBD1 Q8IB03 Crystal Structure of the first nucleotide binding domain of chaperone ClpB1, putative, (Pv089580) from Plasmodium Vivax HTML PDF
2P6N DDX41 Q9UJV9 Human DEAD-box RNA helicase DDX41, helicase domain HTML PDF
2P6X PTPN22 Q9Y2R2 Crystal structure of human tyrosine phosphatase PTPN22 HTML PDF
2P82 ATG4A Q8WYN0 Cysteine protease ATG4A HTML PDF
2P8U HMGCS1 Q01581 Crystal structure of human 3-hydroxy-3-methylglutaryl CoA synthase I HTML PDF
2PA1 PDLIM2 Q96JY6 Structure of the PDZ domain of human PDLIM2 bound to a C-terminal extension from human beta-tropomyosin HTML PDF
2PA5 PTPN9 P43378 Crystal structure of human protein tyrosine phosphatase PTPN9 HTML PDF
2PBC FKBP2 P26885 FK506-binding protein 2 HTML PDF
2PBF Pf-PCMT Q8ILD5 Crystal structure of a putative protein-L-isoaspartate O-methyltransferase beta-aspartate methyltransferase (PCMT) from Plasmodium falciparum in complex with S-adenosyl-L-homocysteine HTML PDF
2PD0 cgd2_2020 Q5CTR0 Protein cgd2_2020 from Cryptosporidium parvum HTML PDF
2PD6 HSD17B8 Q92506 Structure of human hydroxysteroid dehydrogenase type 8, HSD17B8 HTML PDF
2PFR NAT2 P11245 Human N-acetyltransferase 2 HTML PDF
2PKT PDLIM1 O00151 Crystal structure of the human CLP-36 (PDLIM1) bound to the C-terminal peptide of human alpha-actinin-1 HTML PDF
2PL3 DDX10 Q13206 Human DEAD-box RNA helicase DDX10, DEAD domain in complex with ADP HTML PDF
2PLA KIAA0089 Q8N335 Crystal structure of human glycerol-3-phosphate dehydrogenase 1-like protein HTML PDF
2PLU Cp-CyP (cgd2_4120) A3FQA7 Crystal structure of Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_4120 HTML PDF
2PLW Pf-FtsJ Q8IEL9 Crystal structure of a ribosomal RNA methyltransferase, putative, from Plasmodium falciparum (PF13_0052). HTML PDF
2PMY RASEF Q8IZ41 EF-hand domain of human RASEF HTML PDF
2PN8 PRDX4 Q13162 Crystal structure of human peroxiredoxin 4 (thioredoxin peroxidase) HTML PDF
2PNT GRASP Q7Z6J2 Crystal structure of the PDZ domain of human GRASP (GRP1) in complex with the C-terminal peptide of the metabotropic glutamate receptor type 1 HTML PDF
2PNY IDI2 Q9BXS1 Structure of Human Isopentenyl-diphosphate Delta-isomerase 2 HTML PDF
2POE Cp-CyPJ (cgd2_1660) A3FQ68 Crystal structure of Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_1660 HTML PDF
2PPI GAN Q9H2C0 Structure of the BTB (Tramtrack and Bric a brac) domain of human Gigaxonin HTML PDF
2PPL PNLIPRP1 P54315 Human Pancreatic lipase-related protein 1 HTML PDF
2PQ5 DUSP13 Q9UII6 Crystal structure of Dual specificity protein phosphatase 13 (DUSP13) HTML PDF
2PQ8 MYST1 Q9H7Z6 MYST histone acetyltransferase 1 HTML PDF
2PQF PARP12 Q9H0J9 Human Poly(ADP-Ribose) Polymerase 12, Catalytic fragment in complex with an inhibitor 3-Aminobenzoic acid HTML PDF
2PQO (superseded by 3C0Z) HDAC7 Q8WUI4 Crystal structure of catalytic domain of human histone deacetylase HDAC7 in complex with SAHA HTML PDF
2PQP (superseded by 3C10) HDAC7 Q8WUI4 Crystal structure of catalytic domain of human histone deacetylase HDAC7 in complex with Trichostatin A (TSA) HTML PDF
2PQT NAT1 P18440 Human N-acetyltransferase 1 HTML PDF
2PQW L3MBTL Q9Y468 Crystal structure of L3MBTL1 in complex with H4K20Me2 (residues 17-25), trigonal form HTML PDF
2PSO STARD13 Q9Y3M8 Human StarD13 (DLC2) lipid transfer and protein localization domain HTML PDF
2PSS Pf-SRM + dcAdoMET + 4MCHA Q8II73 The structure of Plasmodium falciparum spermidine synthase in its apo-form HTML PDF
2PT6 Pf-SRM Q8II73 The structure of Plasmodium falciparum spermidine synthase in complex with decarboxylated S-adenosylmethionine HTML PDF
2PT9 Pf-SRM + dcAdoMet Q8II73 The structure of Plasmodium falciparum spermidine synthase in complex with decarboxylated S-adenosylmethionine and the inhibitor cis-4-methylcyclohexylamine (4MCHA) HTML PDF
2PWP Pf-SRM + spermidine Q8II73 Crystal structure of spermidine synthase from Plasmodium falciparum in complex with spermidine HTML PDF
2PWQ Py-E2-25 Q7RP52 Crystal structure of a putative ubiquitin conjugating enzyme from Plasmodium yoelii HTML PDF
2PXX MGC2408 P0DPD7 Human putative methyltransferase MGC2408 HTML PDF
2Q0N PAK4 O96013 Structure of human p21 activating kinase 4 (PAK4) in complex with a consensus peptide HTML PDF
2Q0V Pf-UEV1a O97241 Crystal structure of ubiquitin conjugating enzyme E2, putative, from Plasmodium falciparum HTML PDF
2Q2F SELS Q9BQE4 Structure of the human Selenoprotein S (VCP-interacting membrane protein) HTML PDF
2Q2G Cp-HSP40 A3FQ69 Crystal structure of dimerization domain of HSP40 from Cryptosporidium parvum, cgd2_1800 HTML PDF
2Q3E UGDH O60701 Structure of human UDP-glucose dehydrogenase complexed with NADH and UDP-glucose HTML PDF
2Q3F RRAGD Q9NQL2 X-ray crystal structure of putative human Ras-related GTP binding D in complex with GMPPNP HTML PDF
2Q3G PDLIM7 Q9NR12 Structure of the PDZ domain of human PDLIM7 bound to a C-terminal extension from human beta-tropomyosin HTML PDF
2Q3H RHOU Q7L0Q8 The crystal structure of RhouA in the GDP-bound state. HTML PDF
2Q80 GGPS1 O95749 Crystal structure of human geranylgeranyl pyrophosphate synthase bound to GGPP HTML PDF
2Q8L Pf-OMPDC Q8IJH3 Crystal structure of orotidine 5'-phosphate decarboxylase from Plasmodium falciparum HTML PDF
2Q9V MAGI1 Q96QZ7 Crystal structure of the C890S mutant of the 4th PDZ domain of human membrane associated guanylate kinase HTML PDF
2QC8 GS + MSO-P P15104 Crystal structure of human glutamine synthetase in complex with ADP and methionine sulfoximine phosphate HTML PDF
2QEP PTPRN2 Q92932 Crystal structure of the D1 domain of PTPRN2 (IA2beta) HTML PDF
2QFE CAPN7 Q9Y6W3 Distal C2-Like Domain of Human Calpain-7 HTML PDF
2QFZ TBC1D22A Q8WUA7 Crystal structure of human TBC1 domain family member 22A HTML PDF
2QG1 MPDZ (11th domain) O75970 Crystal structure of the 11th PDZ domain of MPDZ (MUPP1) HTML PDF
2QG4 UGDH O60701 Crystal structure of human UDP-glucose dehydrogenase product complex with UDP-glucuronate HTML PDF
2QG5 Cp-CDPK (cgd7_1840) Q5CYL9 Cryptosporidium parvum calcium dependent protein kinase cgd7_1840 HTML PDF
2QG7 Pv-EK A5K4Q6 Plasmodium vivax ethanolamine kinase Pv091845 HTML PDF
2QGX UBE2Q1 Q7Z7E8 Ubiquitin-conjugating enzyme E2Q HTML PDF
2QIS FDPS P14324 Crystal structure of human farnesyl pyrophosphate synthase T210S mutant bound to risedronate HTML PDF
2QK4 GART P22102 Human glycinamide ribonucleotide synthetase HTML PDF
2QKQ EPHB4 P54760 Structure of the SAM Domain of Human Ephrin Type-B Receptor 4 HTML PDF
2QKR Cp-CDK (cgd5_2510) Q5CRJ8 Cryptosporidium parvum cyclin-dependent kinase cgd5_2510 with indirubin 3'-monoxime bound HTML PDF
2QME RAC3 + PAK1 P60763, Q13153 Crystal structure of human RAC3 in complex with CRIB domain of human p21-activated kinase 1 (PAK1) HTML PDF
2QNR 2-Sep Q15019 Human septin 2 in complex with GDP HTML PDF
2QNW Tg-ACP O77470 Toxoplasma gondii apicoplast-targeted acyl carrier protein HTML PDF
2QOD EPHA3 P29320 Human EphA3 kinase and juxtamembrane region, Y602F mutant HTML PDF
2QOF EPHA3 P29320 Human EphA3 kinase and juxtamembrane region, Y596F mutant HTML PDF
2QOI EPHA3 P29320 Human EphA3 kinase and juxtamembrane region, Y596F:Y602F double mutant HTML PDF
2QOK EPHA3 P29320 Human EphA3 kinase and juxtamembrane region, Y596F:Y602F:S768A triple mutant HTML PDF
2QOL EPHA3 P29320 Human EphA3 kinase and juxtamembrane region, Y596:Y602:S768G triple mutant HTML PDF
2QON EPHA3 P29320 Human EphA3 kinase and juxtamembrane region, Y596F:Y602F:Y742A triple mutant HTML PDF
2QOO EPHA3 P29320 Human EphA3 kinase and juxtamembrane region, Y596F:Y602F:Y742F triple mutant HTML PDF
2QPW PRDM2 Q13029 Methyltransferase domain of human PR domain-containing protein 2 HTML PDF
2QQ2 ACOT7 O00154 Crystal structure of C-terminal domain of Human acyl-CoA thioesterase 7 HTML PDF
2QQ5 DHRS1 Q96LJ7 Crystal structure of human SDR family member 1 HTML PDF
2QQ8 TBC1D14 Q9P2M4 Crystal structure of the putative RabGAP domain of human TBC1 domain family member 14 HTML PDF
2QU8 Pf-NOG1 Q6LFE0 Crystal structure of putative nucleolar GTP-binding protein 1 PFF0625w from Plasmodium falciparum HTML PDF
2QZ4 SPG7 Q9UQ90 Human paraplegin, AAA domain in complex with ADP HTML PDF
2R0J Pf-UBC13 Q8I3J4 Crystal structure of the putative ubiquitin conjugating enzyme, PFE1350c, from Plasmodium falciparum HTML PDF
2R2O PLXNB1 O43157 Crystal structure of the effector domain of human Plexin B1 HTML PDF
2R2P EPHA5 P54756 Kinase domain of human ephrin type-A receptor 5 (EphA5) HTML PDF
2R2Q GABARAPL1 Q9H0R8 Crystal structure of human Gamma-Aminobutyric Acid Receptor-Associated Protein-like 1 (GABARAP1), Isoform CRA_a HTML PDF
2R37 GPX3 P22352 Crystal structure of human glutathione peroxidase 3 (selenocysteine to glycine mutant) HTML PDF
2R3A SUV39H2 Q9H5I1 Methyltransferase domain of human suppressor of variegation 3-9 homolog 2 HTML PDF
2R4H MAGI1 Q96QZ7 Crystal structure of a C1190S mutant of the 6th PDZ domain of human membrane associated guanylate kinase HTML PDF
2R55 STARD5 Q9NSY2 Human StAR-related lipid transfer protein 5 HTML PDF
2R77 Pf-PEBP Q7KQK1 Crystal structure of phosphatidylethanolamine-binding protein, pfl0955c, from Plasmodium falciparum HTML PDF
2RCY Pf-P5CR Q8IDC6 Crystal structure of Plasmodium falciparum pyrroline carboxylate reductase (MAL13P1.284) with NADP bound HTML PDF
2REI EPHA7 Q15375 Kinase domain of human ephrin type-A receptor 7 (Epha7) HTML PDF
2REO SULT1C3 Q6IMI6 Crystal structure of human sulfotransferase 1C3 (Sult1C3) in complex with PAP HTML PDF
2REP (superseded by 5WDH) KIFC1 Q9BW19 Motor domain of human kinesin family member C1 HTML PDF
2REX PLXNB1 + RND1 O43157, Q92730 Crystal structure of the effector domain of PLXNB1 bound with Rnd1 GTPase HTML PDF
2REY DVL2 O14641 Crystal structure of the PDZ domain of human dishevelled 2 (homologous to Drosophila dsh) HTML PDF
2RF0 MAP3K10 Q02779 Crystal structure of human mixed lineage kinase MAP3K10 SH3 domain HTML PDF
2RF5 TNKS1 O95271 Crystal structure of human tankyrase 1- catalytic PARP domain HTML PDF
2RFI EHMT1 Q9H9B1 Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and dimethylated H3K9 peptide HTML PDF
2RFJ BRDT Q58F21 Crystal structure of the bromo domain 1 in human bromodomain containing protein, testis specific (BRDT) HTML PDF
2RHD Cp-Rab1a Q7YYW6 Crystal structure of Cryptosporidium parvum small GTPase RAB1A HTML PDF
2RJC L3MBTL Q9Y468 Crystal structure of L3MBTL1 protein in complex with MES HTML PDF
2RJD L3MBTL Q9Y468 Crystal structure of L3MBTL1 protein HTML PDF
2RJE L3MBTL Q9Y468, P62805 Crystal structure of L3MBTL1 in complex with H4K20Me2 (residues 17-25), orthorhombic form II HTML PDF
2RJF L3MBTL Q9Y468 Crystal structure of L3MBTL1 in complex with H4K20Me2 (residues 12-30), orthorhombic form I HTML PDF
2UV2 SLK + K00606a Q9H2G2 Crystal Structure Of Human Ste20-Like Kinase Bound To 4-(4-(5- Cyclopropyl-1H-pyrazol-3-ylamino)-quinazolin-2-ylamino)-phenyl)- acetonitrile HTML PDF
2UVL BIRC3 Q13489 Human BIR3 domain of Baculoviral Inhibitor of Apoptosis Repeat- Containing 3 (BIRC3) HTML PDF
2UVQ UCK1 Q9HA47 Crystal structure of human uridine-cytidine kinase 1 in complex with ADP HTML PDF
2UW2 RRM2 P31350 Crystal structure of human ribonucleotide reductase subunit R2 HTML PDF
2UX0 CAMK2G Q13555 Structure of the oligomerisation domain of calcium-calmodulin dependent protein kinase II gamma HTML PDF
2UXW ACADVL P49748 Crystal structure of human very long chain acyl-CoA dehydrogenase (ACADVL) HTML PDF
2UYY NPAC Q49A26 Structure of the cytokine-like nuclear factor n-pac HTML PDF
2UZ9 GUAD Q9Y2T3 Human guanine deaminase (guaD) in complex with zinc and its product Xanthine. HTML PDF
2UZC PDLIM5 Q96HC4 Structure of human PDLIM5 in complex with the C-terminal peptide of human alpha-actinin-1 HTML PDF
2UZP PRKCG, C2 domain P05129 Crystal structure of the C2 domain of human protein kinase C gamma. HTML PDF
2V1W PDLIM4 P50479 Crystal structure of human LIM protein RIL (PDLIM4) PDZ domain bound to the C-terminal peptide of human alpha-actinin-1 HTML PDF
2V1X RECQL P46063 Crystal structure of human RECQ-like DNA helicase HTML PDF
2V24 SPSB4 Q96A44 Structure of the human SPRY domain-containing SOCS box protein SSB-4 HTML PDF
2V40 ADSS2 P30520 Human Adenylosuccinate synthetase isozyme 2 in complex with GDP HTML PDF
2V4M GFPT1 Q06210 The isomerase domain of human glutamine-fructose-6-phosphate transaminase 1 (GFPT1) in complex with fructose 6-phosphate HTML PDF
2V4U CTPS2 Q9NRF8 Human CTP synthetase 2 - glutaminase domain in complex with 5-OXO-L- NORLEUCINE HTML PDF
2V4W (superseded by 2WYA) HMGCS2 P54868 CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL 3-HYDROXY-3-METHYLGLUTARYL- COENZYME A SYNTHASE 2 (HMGCS2) HTML PDF
2V4Z RGS2 + Galphai3 P08754, P41220 The crystal structure of the human G-protein subunit alpha (GNAI3) in complex with an engineered regulator of G-protein signaling type 2 domain (RGS2) HTML PDF
2V62 VRK2 Q86Y07 Structure of vaccinia-related kinase 2 HTML PDF
2V7O CAMK2G Q13555 Crystal structure of human calcium-calmodulin-dependent protein kinase II gamma HTML PDF
2V90 PDZD3 Q86UT5 Crystal structure of the 3rd PDZ domain of intestine- and kidney- enriched PDZ domain IKEPP (PDZD3) HTML PDF
2V9Y GART P22102 Human aminoimidazole ribonucleotide synthetase HTML PDF
2VAC PTK9L (1st. cofilin domain) Q6IBS0 Structure of N-terminal Actin Depolymerizing Factor homology (ADF-H) domain of human twinfilin-2 HTML PDF
2VAG CLK1 P49759 Crystal structure of di-phosphorylated human CLK1 in complex with a novel substituted indole inhibitor HTML PDF
2VD5 DMPK1 Q09013 Structure of Human Myotonic Dystrophy Protein Kinase in Complex with the Bisindoylmaleide inhibitor BIM VIII HTML PDF
2VD6 ADSL P30566 Human adenylosuccinate lyase in complex with its substrate N6-(1,2- Dicarboxyethyl)-AMP, and its products AMP and fumarate. HTML PDF
2VD7 JMJD2A + inhibitor O75164 Crystal Structure of JMJD2A complexed with inhibitor Pyridine-2,4- dicarboxylic acid HTML PDF
2VIF SOCS6 + phosphopeptide O14544, P10721 Crystal structure of SOCS6 SH2 domain in complex with a c-KIT phosphopeptide HTML PDF
2VIG ACADS P16219 Crystal structure of human short-chain acyl CoA dehydrogenase HTML PDF
2VKP BTBD6 Q96KE9 Crystal structure of BTB domain from BTBD6 HTML PDF
2VKT CTPS2 Q9NRF8 HUMAN CTP SYNTHETASE 2 - GLUTAMINASE DOMAIN HTML PDF
2VM5 BIRC1 Q13075 HUMAN BIR2 DOMAIN OF BACULOVIRAL INHIBITOR OF APOPTOSIS REPEAT- CONTAINING 1 (BIRC1) HTML PDF
2VM6 BCL2A1 Q16548, O43521 Human Bcl2-A1 in complex with Bim-BH3 peptide HTML PDF
2VN8 RTN4IP1 + NADPH Q8WWV3 Crystal structure of human Reticulon 4 interacting protein 1 in complex with NADPH HTML PDF
2VN9 CAMK2D Q13557 Crystal Structure of Human Calcium Calmodulin dependent Protein Kinase II delta isoform 1, CAMKD HTML PDF
2VNA ZADH1 Q8N8N7 Structure of Human Zinc-binding Alcohol Dehydrogenase 1 (ZADH1) HTML PDF
2VPH PTPN4 P29074 Crystal structure of the human protein tyrosine phosphatase, non- receptor type 4, PDZ domain HTML PDF
2VPI GMPS P49915 Human GMP synthetase - glutaminase domain HTML PDF
2VPJ KLHL12 Q53G59 Crystal structure of the Kelch domain of human KLHL12 HTML PDF
2VPK MYNN Q9NPC7 Crystal structure of the BTB domain of human myoneurin HTML PDF
2VR2 DHP Q14117 Human Dihydropyrimidinase HTML PDF
2VRE ECH1 Q13011 crystal structure of human peroxisomal delta3,5,delta2,4-dienoyl coa isomerase HTML PDF
2VRF SNTB2 Q13425 CRYSTAL STRUCTURE OF THE HUMAN BETA-2-SYNTROPHIN PDZ DOMAIN HTML PDF
2VSP PDZK1 Q5T2W1 Crystal structure of the fourth PDZ domain of PDZ domain-containing protein 1 HTML PDF
2VSV RHPN2 Q8IUC4 Crystal structure of the PDZ domain of human rhophilin-2 HTML PDF
2VSW DUSP16 Q9BY84 The structure of the rhodanese domain of the human dual specificity phosphatase 16 HTML PDF
2VUW GSG2 + K00224 Q8TF76 Structure of human haspin kinase domain HTML PDF
2VUX RRM2B Q7LG56 Human ribonucleotide reductase, subunit M2 B HTML PDF
2VWR LNX2 (2nd PDZ domain) Q8N448 Crystal structure of the second pdz domain of numb-binding protein 2 HTML PDF
2VX2 ECHDC3 Q96DC8 Crystal structure of human enoyl Coenzyme A hydratase domain- containing protein 3 (ECHDC3) HTML PDF
2VX3 DYRK1A + K00611a Q13627 Crystal structure of the human dual specificity tyrosine- phosphorylation-regulated kinase 1A HTML PDF
2VXO GMPS P49915 Human GMP synthetase in complex with XMP HTML PDF
2VZ5 TAX1BP3 O14907 Structure of the PDZ domain of Tax1 (human T-cell leukemia virus type I) binding protein 3 HTML PDF
2VZ6 CAMK2A Q9UQM7 Structure of human calcium calmodulin dependent protein kinase type II alpha (CAMK2A) in complex with Indirubin E804 HTML PDF
2VZE LOC148158 (L64P) + AMP Q08AH3 Crystal structure of human acyl-CoA synthetase medium-chain family member 2A (L64P mutation) in complex with AMP HTML PDF
2W0I PTK9L (2nd ADF-H domain) Q6IBS0 Structure Of C-Terminal Actin Depolymerizing Factor Homology (Adf-H) Domain Of Human Twinfilin-2 HTML PDF
2W2C CAMK2D association domain Q13557 STRUCTURE OF THE TETRADECAMERIC OLIGOMERISATION DOMAIN OF CALCIUM- CALMODULIN DEPENDENT PROTEIN KINASE II DELTA HTML PDF
2W2I JMJD2E (LOC390245) + 2,4-PDCA B2RXH2 Crystal structure of the human 2-oxoglutarate oxygenase LOC390245 HTML PDF
2W2J CA8 P35219 Crystal structure of the human carbonic anhydrase related protein VIII HTML PDF
2W4F SCRIB1 Q14160 CRYSTAL STRUCTURE OF THE FIRST PDZ DOMAIN OF HUMAN SCRIB1 HTML PDF
2W4L DCTD P32321 Human dCMP deaminase HTML PDF
2W4M NANP Q8TBE9 The Crystal Structure of human N-acetylneuraminic acid phosphatase, NANP HTML PDF
2W4O CAMK4 Q16566 Crystal structure of Human CAMK4 in complex with 4-Amino(sulfamoyl- phenylamino)-triazole-carbothioic acid (2,6-difluoro-phenyl)-amide) HTML PDF
2W4Q ZADH1 Q8N8N7 Crystal structure of human zinc-binding alcohol dehydrogenase 1 (ZADH1) in ternary complex with NADP and 18beta-glycyrrhetinic acid HTML PDF
2W7R MAST4 (1st PDZ domain) O15021 Structure of the PDZ domain of Human Microtubule associated serine- threonine kinase 4 HTML PDF
2W7T TBCTPS Q4GZ95 Trypanosoma brucei CTPS - glutaminase domain with bound acivicin HTML PDF
2W98 ZADH1 + phenylbutazone Q8N8N7 CRYSTAL STRUCTURE OF HUMAN ZINC-BINDING ALCOHOL DEHYDROGENASE 1 (ZADH1) IN TERNARY COMPLEX WITH NADP AND PHENYLBUTAZONE HTML PDF
2WA0 MAGEA4 P43358 Crystal structure of the human MAGEA4 HTML PDF
2WBI ACAD11 Q709F0 Crystal structure of human acyl-CoA dehydrogenase 11 HTML PDF
2WD9 ACSM2B Q08AH3 CRYSTAL STRUCTURE OF HUMAN ACYL-COA SYNTHETASE MEDIUM-CHAIN FAMILY MEMBER 2A (L64P MUTATION) IN COMPLEX WITH IBUPROFEN HTML PDF
2WEF BPNT1 O95861 Human 3'(2'), 5'-bisphosphate nucleotidase 1 (BPNT1) in complex with AMP, PO4 and Magnesium HTML PDF
2WEI CpCDPK4 A3FQ16 Crystal structure of the kinase domain of Cryptosporidium parvum calcium dependent protein kinase in complex with 3-MB-PP1 HTML PDF
2WEK MGC45594 + diclofenac Q8N4Q0 Crystal structure of the human MGC45594 gene product in complex with diclofenac HTML PDF
2WEL CAMK2D+SU6656+calmodulin Q13557, P0DP23 Crystal structure of SU6656-bound calcium/calmodulin-dependent protein kinase II delta in complex with calmodulin HTML PDF
2WEM (superseded by 2WUL) GLRX5 Q86SX6 CRYSTAL STRUCTURE OF THE HUMAN GLUTAREDOXIN 5 WITH BOUND GLUTATHIONE IN AN FES CLUSTER HTML PDF
2WGH RRM1 P23921 Human Ribonucleotide reductase R1 subunit (RRM1) in complex with dATP and Mg. HTML PDF
2WH5 ACBD4 + stearoyl-CoA Q8NC06 Crystal structure of human acyl-CoA binding domain 4 complexed with stearoyl-CoA HTML PDF
2WM3 NMRAL1 + NADP + niflumic acid Q9HBL8 Crystal structure of NmrA-like family domain containing protein 1 in complex with niflumic acid HTML PDF
2WM8 MGC5987 Q86V88 Crystal structure of human magnesium-dependent phosphatase 1 of the haloacid dehalogenase superfamily (MGC5987) HTML PDF
2WMD NMRAL1+ NADP + nicotinic acid Q9HBL8 Crystal structure of NmrA-like family domain containing protein 1 in complex with NADP and 2-(4-chloro-phenylamino)-nicotinic acid HTML PDF
2WNS UMPS P11172 Human Orotate phosphoribosyltransferase (OPRTase) domain of Uridine 5' -monophosphate synthase (UMPS) in complex with its substrate orotidine 5'-monophosphate (OMP) HTML PDF
2WNT RPS6KA1 Q15418 Crystal Structure of the Human Ribosomal protein S6 kinase HTML PDF
2WO6 DYRK1A + consensus peptide Q13627, Q5IJ48 Human Dual-Specificity Tyrosine-Phosphorylation-Regulated Kinase 1A in complex with a consensus substrate peptide HTML PDF
2WU6 CLK3 + DKI P49761 Crystal Structure of the Human CLK3 in complex with DKI HTML PDF
2WU7 CLK3 + V25 P49761 Crystal Structure of the Human CLK3 in complex with V25 HTML PDF
2WUL GLRX5 Q86SX6 CRYSTAL STRUCTURE OF THE HUMAN GLUTAREDOXIN 5 WITH BOUND GLUTATHIONE IN AN FES CLUSTER HTML PDF
2WWE PIK3C2G O75747 Crystal structure of the phox homology domain of human phosphoinositide-3-kinase-C2-gamma HTML PDF
2WWP PTGDS P41222 Crystal structure of the human lipocalin-type prostaglandin D synthase HTML PDF
2WWU PHF8 Q9UPP1 Crystal structure of the catalytic domain of PHD finger protein 8 HTML PDF
2WWW MMAA + Z00118 Q8IVH4 Crystal Structure of Methylmalonic Acidemia Type A Protein HTML PDF
2WWY RECQL + dsDNA P46063 Structure of human RECQ-like helicase in complex with a DNA substrate HTML PDF
2WYA HMGCS2 P54868 CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL 3-HYDROXY-3-METHYLGLUTARYL- COENZYME A SYNTHASE 2 (HMGCS2) HTML PDF
2WZ1 GUCY1B3 Q02153 STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN SOLUBLE GUANYLATE CYCLASE 1 BETA 3. HTML PDF
2WZ9 TXNL2 O76003 Crystal structure of the thioredoxin domain of human TXNL2 HTML PDF
2WZK CUL5 Q9D5V5 Structure of the Cul5 N-terminal domain at 2.05A resolution. HTML PDF
2X18 AKT3 (PH domain) Q9Y243 The crystal structure of the PH domain of human AKT3 protein kinase HTML PDF
2X1H MGC45594 + raloxifene Q8N4Q0 Crystal structure of the human MGC45594 gene product in complex with raloxifene HTML PDF
2X47 MACROD1 Q9BQ69 Crystal structure of human MACROD1 HTML PDF
2X4D LHPP Q9H008 Crystal structure of human phospholysine phosphohistidine inorganic pyrophosphate phosphatase LHPP HTML PDF
2X4F LOC340156 Q86YV6 The Crystal Structure of the human myosin light chain kinase LOC340156. HTML PDF
2X57 VIPR2 (GPCR extracellular domain) P41587 Crystal structure of the extracellular domain of human Vasoactive intestinal polypeptide receptor 2 HTML PDF
2X5Y ZC3HAV1 Q7Z2W4 Human ZC3HAV1 (ARTD13), C-terminal domain HTML PDF
2X7F TNIK Q9UKE5 Crystal structure of the kinase domain of human Traf2- and Nck- interacting Kinase with Wee1Chk1 inhibitor HTML PDF
2X7G SRPK2 P78362 Structure of human serine-arginine-rich protein-specific kinase 2 (SRPK2) bound to purvalanol B HTML PDF
2X7H MGC45594 + NADP + fenoprofen (FUP) Q8N4Q0 Crystal structure of the human MGC45594 gene product in complex with fenoprofen HTML PDF
2X8A NVL O15381 Human Nuclear Valosin containing protein Like (NVL), C-terminal AAA- ATPase domain HTML PDF
2XAI (superseded by 3ZKJ) ASB9 + Elongin BC Q15369, Q15370, Q96DX5 Crystal Structure of Ankyrin Repeat and Socs Box-Containing Protein 9 (Asb9) in Complex with Elonginb and Elonginc HTML PDF
2XD7 H2AFY2 Q9P0M6 Crystal structure of the macro domain of human core histone H2A HTML PDF
2XDG GHRHR Q02643 Crystal structure of the extracellular domain of human growth hormone releasing hormone receptor. HTML PDF
2XDP JMJD2C Q9H3R0 Crystal structure of the tudor domain of human JMJD2C HTML PDF
2XDV MINA Q8IUF8 Crystal Structure of the Catalytic Domain of FLJ14393 HTML PDF
2XIJ MUT + adenosylcobalamin P22033 Crystal structure of human methylmalonyl-CoA mutase in complex with adenosylcobalamin HTML PDF
2XIK YSK1 O00506 Structure of Human YSK1 (Yeast Sps1-Ste20-related Kinase 1) HTML PDF
2XIO TATDN1 Q6P1N9 Structure of putative deoxyribonuclease TATDN1 isoform a HTML PDF
2XIQ MUT + adenosylcobalamin + malonyl CoA P22033 Crystal structure of human methylmalonyl-CoA mutase in complex with adenosylcobalamin and malonyl-CoA HTML PDF
2XML JMJD2C Q9H3R0 Crystal structure of human JMJD2C catalytic domain HTML PDF
2XN4 KLHL2 O95198 Crystal structure of the kelch domain of human KLHL2 (Mayven) HTML PDF
2XRF UPASE2 O95045 Crystal structure of human uridine phosphorylase 2 HTML PDF
2XRI ERI3 O43414 Crystal structure of human ERI1 exoribonuclease 3 HTML PDF
2XS6 PIK3R2 O00459 CRYSTAL STRUCTURE OF THE RHOGAP DOMAIN OF HUMAN PIK3R2 HTML PDF
2XSN TH P07101 Crystal Structure of Human Tyrosine Hydroxylase Catalytic Domain HTML PDF
2XST LCN15 Q6UWW0 Crystal Structure of the Human Lipocalin 15 HTML PDF
2XSW INPP5E Q9NRR6 Crystal structure of human INPP5E HTML PDF
2XSX ENO3 P13929 Crystal structure of human beta enolase ENOB HTML PDF
2XVS TTC5 Q8N0Z6 Crystal structure of human TTC5 (Strap) C-terminal OB domain HTML PDF
2XVT RAMP2 O60895 Structure of the extracellular domain of human RAMP2 HTML PDF
2XWC TP73 O15350 Crystal structure of the DNA binding domain of human TP73 refined at 1.8 A resolution HTML PDF
2XXZ JMJD3 O15054 Crystal structure of the human JMJD3 jumonji domain HTML PDF
2XYN ABL2 + VX-680 P42684 HUMAN ABL2 IN COMPLEX WITH AURORA KINASE INHIBITOR VX-680 HTML PDF
2XZZ TGM1 P22735 Crystal structure of the human transglutaminase 1 beta-barrel domain HTML PDF
2Y05 LTB4DH Q14914 Crystal structure of human leukotriene B4 12-hydroxydehydrogenase in complex with NADP and raloxifene HTML PDF
2Y1H TATDN3 Q17R31 Crystal structure of the human TatD-domain protein 3 (TATDN3) HTML PDF
2Y7B ANLN Q9NQW6 Crystal structure of the PH domain of human Actin-binding protein anillin ANLN HTML PDF
2Y7J PHKG2 P15735 Structure of human phosphorylase kinase, gamma 2 HTML PDF
2YAD SFTPC P11686 BRICHOS domain of Surfactant protein C precursor protein HTML PDF
2YAN TXNL2 O76003 Crystal structure of the second glutaredoxin domain of human TXNL2 HTML PDF
2YBX PIP4K2A P48426 Crystal Structure of Human Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha HTML PDF
2YD0 ERAP1 Q9NZ08 Crystal structure of the soluble domain of human endoplasmic reticulum aminopeptidase 1 ERAP1 HTML PDF
2YDX MAT2B Q9NZL9 Crystal structure of human S-adenosylmethionine synthetase 2, beta subunit HTML PDF
2YDY MAT2B Q9NZL9 Crystal structure of human S-adenosylmethionine synthetase 2, beta subunit in Orthorhombic crystal form HTML PDF
2YF0 MTMR6 Q9Y217 Human Myotubularin related protein 6 (MTMR6) HTML PDF
2YGW MLYCD O95822 Crystal structure of human MCD HTML PDF
2YL2 ACACA Q13085 Crystal structure of human acetyl-CoA carboxylase 1, biotin carboxylase (BC) domain HTML PDF
2YPR FEV Q99581 Crystal structure of the DNA binding ETS domain of human protein FEV HTML PDF
2YPS SNX3 O60493 Crystal structure of the PX domain of human sorting nexin 3 HTML PDF
2YPT ZMPSTE24 O75844, P02545 Crystal structure of the human nuclear membrane zinc metalloprotease ZMPSTE24 mutant (E336A) in complex with a synthetic CSIM tetrapeptide from the C-terminus of prelamin A HTML PDF
2Z5F SULT1B1 O43704 Human sulfotransferase Sult1b1 in complex with PAP HTML PDF
2ZFY OTUB1 Q96FW1 Crystal structure of human Otubain 1 HTML PDF
3B6E MDA5 Q9BYX4 Crystal structure of human DECH-box RNA Helicase MDA5 (Melanoma differentiation-associated protein 5), DECH-domain HTML PDF
3B6N Pv-MECPS A5KBP6 Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase PV003920 from Plasmodium vivax HTML PDF
3B6U KIF3B O15066 Crystal structure of the motor domain of human kinesin family member 3B in complex with ADP HTML PDF
3B6V KIF3C O14782 Crystal structure of the motor domain of human kinesin family member 3C in complex with ADP HTML PDF
3B76 LNX1 Q8TBB1 Crystal structure of the third PDZ domain of human ligand-of-numb protein-X (LNX1) in complex with the C-terminal peptide from the coxsackievirus and adenovirus receptor HTML PDF
3B7G DDX20 + AMPPNP Q9UHI6 Human DEAD-box RNA helicase DDX20, Conserved domain I (DEAD) in complex with AMPPNP (Adenosine-(Beta,gamma)-imidotriphosphate) HTML PDF
3B7K ACOT12 Q8WYK0 Human Acyl-coenzyme A thioesterase 12 HTML PDF
3B7L FDPS + minodronate P14324 Human farnesyl diphosphate synthase complexed with MG and minodronate HTML PDF
3B7O PTPN11 Q06124 Crystal structure of the human tyrosine phosphatase SHP2 (PTPN11) with an accessible active site HTML PDF
3B7P Pf-SRM-SPM Q8II73 Crystal structure of spermidine synthase from Plasmodium falciparum in complex with spermine HTML PDF
3B7W LOC148158 Q08AH3 Crystal structure of human acyl-CoA synthetase medium-chain family member 2A, with L64P mutation HTML PDF
3B7X FKBP6 O75344 Crystal structure of human FK506-Binding Protein 6 HTML PDF
3B7Y NEDD4 P46934 Crystal structure of the C2 Domain of the E3 Ubiquitin-Protein Ligase NEDD4 HTML PDF
3B84 HKR3 P10074 Crystal structure of the human BTB domain of the Krueppel related Zinc Finger Protein 3 (HKR3) HTML PDF
3BE4 Cp-AK Q5CRC5 Crystal structure of Cryptosporidium parvum adenylate kinase cgd5_3360 HTML PDF
3BER DDX47 Q9H0S4 Human DEAD-box RNA-helicase DDX47, conserved domain I in complex with AMP HTML PDF
3BFK Pf-Rab11a Q76NM4 Crystal structure of Plasmodium falciparum Rab11a in complex with GDP HTML PDF
3BFN (superseded by 6NJE) KIF22 Q14807 Crystal structure of the motor domain of human kinesin family member 22 HTML PDF
3BFO MALT1 Q9UDY8 Crystal structure of Ig-like C2-type 2 domain of the human Mucosa-associated lymphoid tissue lymphoma translocation protein 1 HTML PDF
3BGV RNMT O43148 Crystal structure of mRNA cap guanine-N7 methyltransferase in complex with SAH HTML PDF
3BHD THTPA Q9BU02 Crystal structure of human thiamine triphosphatase (THTPA) HTML PDF
3BHH CAMK2B + inhibitor Q13554 Crystal structure of human calcium/calmodulin-dependent protein kinase IIB isoform 1 (CAMK2B) HTML PDF
3BHY DAPK3 + K01742a O43293 Crystal structure of human death associated protein kinase 3 (DAPK3) in complex with a beta-carboline ligand HTML PDF
3BI7 UHRF1 Q96T88 Crystal structure of the SRA domain of E3 ubiquitin-protein ligase UHRF1 HTML PDF
3BIC MUT P22033 Crystal structure of human methylmalonyl-CoA mutase HTML PDF
3BIN EPB41L3 Q9Y2J2, Q9BY67 Structure of the DAL-1 and TSLC1 (372-383) complex HTML PDF
3BKB FES + staurosporin P07332 Crystal structure of human Feline Sarcoma Viral Oncogene Homologue (v-FES) HTML PDF
3BKP Tg-CyP16L D0VWS4 Crystal structure of the Toxoplasma gondii cyclophilin, 49.m03261 HTML PDF
3BLJ PARP15 Q460N3 Crystal structure of human poly(ADP-ribose) polymerase 15, catalytic fragment HTML PDF
3BO5 SETMAR Q53H47 Crystal structure of methyltransferase domain of human Histone-lysine N-methyltransferase SETMAR HTML PDF
3BO7 Tg-CyPR D0VWS5 Crystal structure of Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, 541.m00136 HTML PDF
3BOR EIF4A2 Q14240 Crystal structure of the DEADc domain of human translation initiation factor 4A-2 HTML PDF
3BPJ EIF3J O75822 Crystal structure of human translation initiation factor 3, subunit 1 alpha HTML PDF
3BPR MERTK Q12866 Crystal structure of catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor C52 HTML PDF
3BPT HIBCH Q6NVY1 Crystal structure of human beta-hydroxyisobutyryl-CoA hydrolase in complex with quercetin HTML PDF
3BPU MAGI1 Q96QZ7 Crystal structure of the 3rd PDZ domain of human membrane associated guanylate kinase, C677S and C709S double mutant HTML PDF
3BQR DAPK3 O43293 Crystal structure of human death associated protein kinase 3 (DAPK3) in complex with an imidazo-pyridazine ligand HTML PDF
3BRB MERTK Q12866 Crystal structure of catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with ADP HTML PDF
3BYI ARHGAP15 Q53QZ3 Crystal structure of human Rho GTPase activating protein 15 (ARHGAP15) HTML PDF
3BYV Tg-ROP8 O15693 Crystal structure of Toxoplasma gondii specific rhoptry antigen kinase domain HTML PDF
3BZH UBE2E1 P51965 Crystal structure of human ubiquitin-conjugating enzyme E2 E1 HTML PDF
3C49 PARP3 Q9Y6F1 Human poly(ADP-ribose) polymerase 3, catalytic fragment in complex with an inhibitor KU0058948 HTML PDF
3C4H PARP3 Q9Y6F1 Human poly(ADP-ribose) polymerase 3, catalytic fragment in complex with an inhibitor DR2313 HTML PDF
3C5C RASL12 Q9NYN1 Crystal structure of human Ras-like, family 12 protein in complex with GDP HTML PDF
3C5E LOC148158 + ATP/AMP Q08AH3 Crystal structure of human acyl-CoA synthetase medium-chain family member 2A (L64P mutation) in complex with ATP HTML PDF
3C5H GRLF1 Q9NRY4 Crystal structure of the Ras homolog domain of human GRLF1 (p190RhoGAP) HTML PDF
3C5I PkChK D0VWT1 Crystal structure of Plasmodium knowlesi choline kinase, PKH_134520 HTML PDF
3C5K HDAC6 Q9UBN7 Crystal structure of human HDAC6 zinc finger domain HTML PDF
3C5N TULP1 O00294 Structure of human TULP1 in complex with IP3 HTML PDF
3C6K SMS P52788 Crystal structure of human spermine synthase in complex with spermidine and 5-methylthioadenosine HTML PDF
3C6M SMS P52788 Crystal structure of human spermine synthase in complex with spermine and 5-methylthioadenosine HTML PDF
3C8X EPHA2 P29317 Crystal structure of the ligand binding domain of human Ephrin A2 (Epha2) receptor protein kinase HTML PDF
3CBL FES + staurosporin + peptide P07332 Crystal structure of human feline sarcoma viral oncogene homologue (v-FES) in complex with staurosporine and a consensus peptide HTML PDF
3CBQ REM2 Q8IYK8 Crystal structure of the human REM2 GTPase with bound GDP HTML PDF
3CC6 PTK2B Q14289 Crystal structure of kinase domain of protein tyrosine kinase 2 beta (PTK2B) HTML PDF
3CC9 Pv-GGPPS+GGPP A5K4U6 Crystal structure of Plasmodium vivax putative polyprenyl pyrophosphate synthase in complex with geranylgeranyl diphosphate HTML PDF
3CD3 FES + staurosporin + peptide P07332 Crystal structure of phosphorylated human feline sarcoma viral oncogene homologue (v-FES) in complex with staurosporine and a consensus peptide HTML PDF
3CE0 PARP3 Q9Y6F1 Human poly(ADP-ribose) polymerase 3, catalytic fragment in complex with an inhibitor PJ34 HTML PDF
3CE7 Tg-mACP D0VWT5 Crystal structure of toxoplasma specific mitochondrial acyl carrier protein, 59.m03510 HTML PDF
3CEG BIRC6 Q9NR09 Crystal structure of the UBC domain of baculoviral IAP repeat-containing protein 6 HTML PDF
3CEK TTK P33981 Crystal structure of human dual specificity protein kinase (TTK) HTML PDF
3CEQ KLC2 Q9H0B6 The TPR domain of Human Kinesin Light Chain 2 (hKLC2) HTML PDF
3CEY L3MBTL2 Q969R5 Crystal structure of L3MBTL2 HTML PDF
3CKK METTL1 Q9UBP6 Crystal structure of human methyltransferase-like protein 1 HTML PDF
3CKL SULT1B1 O43704 Crystal structure of human cytosolic sulfotransferase SULT1B1 in complex with PAP and resveratrol HTML PDF
3CLV Pf-RAB5A O96193 Crystal Structure of Rab5a from plasmodium falciparum, PFB0500c HTML PDF
3CLZ UHRF1 Q96T88 The set and ring associated (SRA) domain of UHRF1 bound to methylated DNA HTML PDF
3COG CTH P32929 Crystal structure of human cystathionase (Cystathionine gamma lyase) in complex with DL-propargylglycine HTML PDF
3CON NRAS P01111 Crystal structure of the human NRAS GTPase bound with GDP HTML PDF
3COS ADH4 P08319 Crystal structure of human class II alcohol dehydrogenase (ADH4) in complex with NAD and Zn HTML PDF
3COU NUDT16 Q96DE0 Crystal structure of human Nudix motif 16 (NUDT16) HTML PDF
3CP6 FDPS + NE58025 P14324 Crystal structure of human farnesyl diphosphate synthase (T201A mutant) complexed with Mg and biphosphonate inhibitor HTML PDF
3CPF EIF5A P63241 Crystal structure of human eukaryotic translation initiation factor EIF5A HTML PDF
3CPS Cp-GAPDH+NAD Q5CWT6 Crystal structure of Cryptosporidium parvum glyceraldehyde-3-phosphate dehydrogenase HTML PDF
3CQV NR1D2 Q14995 Crystal structure of Reverb beta in complex with heme HTML PDF
3CXG PfTrx Q4VWQ3 Crystal structure of Plasmodium falciparum thioredoxin, PFI0790w HTML PDF
3CXL CHN1 P15882 Crystal structure of human chimerin 1 (CHN1) HTML PDF
3CXW PIM1+ peptide + CARB-10 P11309 Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a beta carboline ligand I HTML PDF
3CY2 PIM1 + peptide + CARB-13 P11309 Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a beta carboline ligand II HTML PDF
3CY3 PIM1 + peptide + JNK Inhibitor V P11309 Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and the JNK inhibitor V HTML PDF
3CYN LOC493869 (GPX8) Q8TED1 The structure of human GPX8 HTML PDF
3CZD GLS O94925 Crystal structure of human glutaminase in complex with L-glutamate HTML PDF
3CZU EPHA2-EFNA1 complex P29317, P20827 Crystal structure of the human ephrin A2- ephrin A1 complex HTML PDF
3D3L ALOX12 P18054 The 2.6 A crystal structure of the lipoxygenase domain of human arachidonate 12-lipoxygenase, 12S-type HTML PDF
3D7C GCN5L2 Q92830 Crystal structure of the bromodomain of human GCN5, the general control of amino-acid synthesis protein 5-like 2 HTML PDF
3D8B FIGNL1 Q6PIW4 Crystal structure of human fidgetin-like protein 1 in complex with ADP HTML PDF
3D8H Cp-PGM Q5CXZ9 Crystal structure of phosphoglycerate mutase from Cryptosporidium parvum, cgd7_4270 HTML PDF
3DA2 CA13 Q8N1Q1 X-ray structure of human carbonic anhydrase 13 in complex with inhibitor HTML PDF
3DAI ATAD2 Q6PL18 Crystal structure of the bromodomain of the human ATAD2 HTML PDF
3DAL PRDM1 O75626 Methyltransferase domain of human PR domain-containing protein 1 HTML PDF
3DAX CYP7A1 P22680 Crystal structure of human CYP7A1 HTML PDF
3DAY LOC148158 + AMP-CPP Q08AH3 Crystal structure of human acyl-CoA synthetase medium-chain family member 2A (L64P mutation) in complex with AMP-CPP HTML PDF
3DB3 UHRF1 Q96T88, Q71DI3 Crystal structure of the tandem tudor domains of the E3 ubiquitin-protein ligase UHRF1 in complex with trimethylated histone H3-K9 peptide HTML PDF
3DB4 UHRF1 Q96T88 Crystal structure of the tandem tudor domains of the E3 ubiquitin-protein ligase UHRF1 HTML PDF
3DB5 PRDM4 Q9UKN5 Crystal structure of methyltransferase domain of human PR domain-containing protein 4 HTML PDF
3DBB (superseded by 3F70) L3MBTL2 Q969R5 Crystal structure of L3MBTL2-H4K20me1 complex HTML PDF
3DFA Cp-CDPK1-Pk A3FQ16 Crystal structure of kinase domain of calcium-dependent protein kinase cgd3_920 from Cryptosporidium parvum HTML PDF
3DH1 DEADC1 Q7Z6V5 Crystal structure of human tRNA-specific adenosine-34 deaminase subunit ADAT2 HTML PDF
3DKM HECTD1 Q9ULT8 Crystal structure of the HECTD1 CPH domain HTML PDF
3DKO EPHA7 Q15375 Complex between the kinase domain of human ephrin type-a receptor 7 (epha7) and inhibitor alw-ii-49-7 HTML PDF
3DKP DDX52 Q9Y2R4 Human DEAD-box RNA-helicase DDX52, conserved domain I in complex with ADP HTML PDF
3DL2 UEV3 Q8IX04 Hexagonal structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A HTML PDF
3DLJ CNDP1 Q96KN2 Crystal structure of human carnosine dipeptidase 1 HTML PDF
3DLM SETDB1 Q15047 Crystal structure of Tudor domain of human Histone-lysine N-methyltransferase SETDB1 HTML PDF
3DLX OXCT P55809 Crystal structure of human 3-oxoacid CoA transferase 1 HTML PDF
3DLZ GSG2 + AMP Q8TF76 Crystal structure of human haspin in complex with AMP HTML PDF
3DM1 CBX3 Q13185, Q96KQ7 Crystal structure of the complex of human chromobox homolog 3 (CBX3) with peptide HTML PDF
3DWD ARFGAP1 Q8N6T3 Crystal structure of the ArfGAP domain of human ARFGAP1 HTML PDF
3DWY CREBBP (bromodomain) Q92793 Crystal Structure of the Bromodomain of Human CREBBP HTML PDF
3DXN 541.m00134 Q3HNM6 Crystal structure of the calcium-dependent kinase from toxoplasma gondii, 541.m00134, kinase domain. HTML PDF
3DYD TAT P17735 Human Tyrosine Aminotransferase HTML PDF
3DZ8 RAB3B P20337 Crystal structure of human Rab3B GTPase bound with GDP HTML PDF
3DZO 33.m01398 Q06AK3 Crystal structure of a rhoptry kinase from toxoplasma gondii HTML PDF
3DZQ EPHA3 P29320 Human EphA3 kinase domain in complex with inhibitor AWL-II-38.3 HTML PDF
3DZX (superseded by 6D0S) TBC1D22B Q9NU19 RabGAP domain of human TBC1D22B HTML PDF
3E04 HTML PDF
3E0C DDB1 Q16531 Crystal Structure of DNA Damage-Binding protein 1(DDB1) HTML PDF
3E77 HTML PDF
3E7V GSG2 + K00522 Q8TF76 Crystal Structure of Human Haspin with a pyrazolo-pyrimidine ligand HTML PDF
3E95 HTML PDF
3EAE HDGF2 Q7Z4V5 PWWP domain of human hepatoma-derived growth factor 2 (HDGF2) HTML PDF
3EAP ARHGAP11A Q6P4F7 Crystal structure of the RhoGAP domain of ARHGAP11A HTML PDF
3EB0 cgd4_240 A3FQN0 Crystal Structure of cgd4_240 from cryptosporidium Parvum in complex with indirubin E804 HTML PDF
3EBB PLAP Q9Y263, P55072 PLAP/P97 complex HTML PDF
3EBQ PPPDE1 Q6ICB0 Crystal structure of human PPPDE1 HTML PDF
3EC8 FLJ10324 Q96JH8 The crystal structure of the RA domain of FLJ10324 (RADIL) HTML PDF
3ECI MAP1LC3A Q9H492 Microtubule-associated protein 1 light chain 3 alpha isoform A (MAP1ALC3) HTML PDF
3ELB PCYT2 Q99447 Human CTP: Phosphoethanolamine Cytidylyltransferase in complex with CMP HTML PDF
3EMW SPSB2 Q99619, P09052 Crystal Structure of human splA/ryanodine receptor domain and SOCS box containing 2 (SPSB2) in complex with a 20-residue VASA peptide HTML PDF
3EO2 NET1 Q7Z628 Crystal structure of the RhoGEF domain of human neuroepithelial cell-transforming gene 1 protein HTML PDF
3EO3 GNE Q9Y223 Crystal structure of the N-acetylmannosamine kinase domain of human GNE protein HTML PDF
3EOE 55.m00007 Q969A2 Crystal Structure of Pyruvate Kinase from toxoplasma gondii, 55.m00007 HTML PDF
3EOZ PfPGM Q8I1V2 Crystal Structure of Phosphoglycerate Mutase from Plasmodium Falciparum, PFD0660w HTML PDF
3EP0 PRDM12 Q9H4Q4 Methyltransferase domain of human PR domain-containing protein 12 HTML PDF
3EPP RNMT O43148 Crystal structure of mRNA cap guanine-N7 methyltransferase (RNMT) in complex with sinefungin HTML PDF
3EPY ACBD7 Q8N6N7 Crystal Structure of human acyl-CoA binding domain 7 complexed with palmitoyl-Coa HTML PDF
3EPZ DNMT1 P26358 Structure of the replication foci-targeting sequence of human DNA cytosine methyltransferase DNMT1 HTML PDF
3EQ5 SKIL P12757 Crystal structure of fragment 137 to 238 of the human Ski-like protein HTML PDF
3EQ6 LOC148158 Q08AH3 Crystal structure of human acyl-CoA synthetase medium-chain family member 2A (L64P mutation) in a ternary complex with products HTML PDF
3EWS DDX19 Q9UMR2 Human DEAD-box RNA-helicase DDX19 in complex with ADP HTML PDF
3EZ3 PvGGPPS A5K4U6 Crystal Structure of Plasmodium vivax geranylgeranylpyrophosphate synthase PVX_092040 with zoledronate and IPP bound HTML PDF
3F0W NUMBL Q9Y6R0 Human NUMB-like protein, phosphotyrosine interaction domain HTML PDF
3F2K SETMAR Q53H47 Structure of the transposase domain of human Histone-lysine N-methyltransferase SETMAR HTML PDF
3F2N GSG2 + K00508 Q8TF76 Crystal Structure of Human Haspin with an Imidazo-pyridazine ligand HTML PDF
3F2O SPSB1 Q96BD6, P09052 Crystal Structure of human splA/ryanodine receptor domain and SOCS box containing 1 (SPSB1) in complex with a 20-residue VASA peptide HTML PDF
3F2R CHKA P35790 Crystal structure of human choline kinase alpha in complex with hemicholinium-3 HTML PDF
3F2U CBX1 P83916 Crystal structure of human chromobox homolog 1 (CBX1) HTML PDF
3F3S CRYL1 Q9Y2S2 The Crystal Structure of Human Lambda-Crystallin, CRYL1 HTML PDF
3F3Z CpCDPK8 Q5CYL9 Crystal structure of Cryptosporidium parvum calcium dependent protein kinase cgd7_1840 in presence of indirubin E804 HTML PDF
3F9R Tb10.70.0370 Q38AW2 Crystal Structure of Trypanosoma Brucei phosphomannosemutase, TB.10.700.370 HTML PDF
3FB3 Tb11.01.2886 E3Q1H1 Crystal Structure of Trypanosoma Brucei Acetyltransferase, Tb11.01.2886 HTML PDF
3FDR TDRD2 Q9Y2W6 Crystal structure of TDRD2 HTML PDF
3FDT CBX5 P45973, P68431 Crystal structure of the complex of human chromobox homolog 5 (CBX5) with H3K9(me)3 peptide HTML PDF
3FE1 HSPA6 P17066 Crystal structure of the human 70kDa heat shock protein 6 (Hsp70B') ATPase domain in complex with ADP and inorganic phosphate HTML PDF
3FE2 DDX5 P17844 Human DEAD-BOX RNA helicase DDX5 (P68), conserved domain I in complex with ADP HTML PDF
3FE4 CA6 P23280 Crystal Structure of Human Carbonic Anhydrase vi HTML PDF
3FEG CHKB Q9Y259 Crystal structure of human choline kinase beta in complex with phosphorylated hemicholinium-3 and adenosine nucleotide HTML PDF
3FEH CENTA1 O75689 Crystal structure of full length centaurin alpha-1 HTML PDF
3FEO MBTD1 Q05BQ5 The crystal structure of MBTD1 HTML PDF
3FHB PARP3 Q9Y6F1 Human poly(ADP-ribose) polymerase 3, catalytic fragment in complex with an inhibitor 3-aminobenzoic acid HTML PDF
3FI8 PfChK Q8IM71 Crystal structure of choline kinase from Plasmodium Falciparum, PF14_0020 HTML PDF
3FK2 GRLF1 Q9NRY4 Crystal structure of the RhoGAP domain of human glucocorticoid receptor DNA-binding factor 1 HTML PDF
3FKC ZBTB33 Q86T24 Crystal Structure of Human Zinc finger and BTB domain containing 33 HTML PDF
3FKM (superseded by 5ULC) PF10_0328 Q8IJ72 PLASMODIUM FALCIPARUM BROMODOMAIN-CONTAINING PROTEIN PF10_0328 HTML PDF
3FL2 UHRF1 Q96T88 Crystal structure of the ring domain of the E3 ubiquitin-protein ligase UHRF1 HTML PDF
3FL7 EPHA2 P29317 Crystal structure of the human ephrin A2 ectodomain HTML PDF
3FLG DNMT3B Q9UBC3 The PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 beta HTML PDF
3FLV ACBD5 + stearoyl-CoA Q5T8D3 The crystal structure of human acyl-CoenzymeA binding domain containing 5 HTML PDF
3FM0 CIAO1 O76071 Crystal structure of WD40 protein Ciao1 HTML PDF
3FM8 CENTA1 Q9NQT8, O75689 Crystal structure of full length centaurin alpha-1 bound with the FHA domain of KIF13B (CAPRI target) HTML PDF
3FMD GSG2 + K00084 Q8TF76 Crystal Structure of Human Haspin with an Isoquinoline ligand HTML PDF
3FME MAP2K6 P52564 Crystal Structure of Human Mitogen-Activated Protein Kinase Kinase 6 (MEK6) Activated Mutant (S207D, T211D) HTML PDF
3FO5 ACOT11 Q8WXI4 Human START domain of Acyl-coenzyme A thioesterase 11 (ACOT11) HTML PDF
3FOG SNX17 Q15036 Crystal structure of the PX domain of sorting nexin-17 (SNX17) HTML PDF
3FVY DPP3 Q9NY33 Crystal structure of human Dipeptidyl Peptidase III HTML PDF
3FXT NUDT6 P53370 Crystal structure of the N-terminal domain of human NUDT6 HTML PDF
3G07 (superseded by 5UNA) MEPCE Q7L2J0 Fragment of 7SK snRNA methylphosphate capping enzyme HTML PDF
3G0H DDX19 Q9UMR2 Human dead-box RNA helicase DDX19, in complex with an ATP-analogue and RNA HTML PDF
3G0J PB1 Q86U86 Crystal Structure of the fifth Bromodomain of Human Poly-bromodomain containing protein 1 (PB1) HTML PDF
3G0L BAZ2B Q9UIF8 Crystal Structure of Human Bromodomain Adjacent to Zinc finger domain 2B (BAZ2B) HTML PDF
3G1N HUWE1 Q7Z6Z7 Catalytic domain of the human E3 ubiquitin-protein ligase HUWE1 HTML PDF
3G1U LMSAH Q4Q124 Crystal structure of Leishmania major S-adenosylhomocysteine hydrolase HTML PDF
3G2F BMPR2 Q13873 Crystal structure of the kinase domain of bone morphogenetic protein receptor type II (BMPR2) at 2.35 A resolution HTML PDF
3G2G PKM2 P14618 S437Y Mutant of human muscle pyruvate kinase, isoform M2 HTML PDF
3GBJ KIF13B Q9NQT8 Crystal structure of the motor domain of kinesin KIF13B bound with ADP HTML PDF
3GDQ HSPA1L P34931 Crystal structure of the human 70kDa heat shock protein 1-like ATPase domain in complex with ADP and inorganic phosphate HTML PDF
3GEY PARP15 + PJ34 Q460N3 Crystal structure of human poly(ADP-ribose) polymerase 15, catalytic fragment in complex with an inhibitor Pj34 HTML PDF
3GF9 ITSN2 Q9NZM3 Crystal structure of human Intersectin 2 RhoGEF domain HTML PDF
3GFC RBBP4 Q09028 Crystal Structure of Histone-binding protein RBBP4 HTML PDF
3GFT KRASB P01116 Human K-Ras (Q61H) in complex with a GTP analogue HTML PDF
3GFW TTK + pyrrolopyridine P33981 Crystal Structure of Human Dual Specificity Protein Kinase (TTK) in complex with a pyrolo-pyridin ligand HTML PDF
3GG3 PCAF Q92831 Crystal Structure of the Bromodomain of Human PCAF HTML PDF
3GG6 NUDT18 Q6ZVK8 Crystal structure of the NUDIX domain of human NUDT18 HTML PDF
3GG8 55.m00007 Q969A2 Crystal structure of the Toxoplasma gondii Pyruvate Kinase N terminal truncated HTML PDF
3GGE GIPC2 Q8TF65 Crystal structure of the PDZ domain of PDZ domain-containing protein GIPC2 HTML PDF
3GGF MST4 Q9P289 Crystal structure of human Serine/threonine-protein kinase MST4 in complex with an quinazolin HTML PDF
3GOY PARP14 Q460N5 Crystal structure of human poly(adp-ribose) polymerase 14, catalytic fragment in complex with an inhibitor 3-aminobenzamide HTML PDF
3GP0 MAPK11+ nilotinib Q15759 Crystal Structure of Human Mitogen Activated Protein Kinase 11 (p38 beta) in complex with Nilotinib HTML PDF
3GPC LOC148158 Q08AH3 Crystal structure of human Acyl-CoA synthetase medium-chain family member 2A (L64P mutation) in a complex with CoA HTML PDF
3GQY PKM2 P14618 Activator-Bound Structure of Human Pyruvate Kinase M2 HTML PDF
3GR4 PKM2 P14618 Activator-Bound Structure of Human Pyruvate Kinase M2 HTML PDF
3GRO PPT1 P50897 Human palmitoyl-protein thioesterase 1 HTML PDF
3GUC UBA05 Q9GZZ9 Human Ubiquitin-activating Enzyme 5 in Complex with AMPPNP HTML PDF
3GUE Tb10.389.0330 Q388T4 Crystal Structure of UDP-glucose phosphorylase from Trypanosoma Brucei, (Tb10.389.0330) HTML PDF
3GV4 HDAC6 Q9UBN7 Crystal structure of human HDAC6 zinc finger domain and ubiquitin C-terminal peptide RLRGG HTML PDF
3GV6 CBX6 O95503, P84233 Crystal Structure of human chromobox homolog 6 (CBX6) with H3K9 peptide HTML PDF
3GVP KIAA0828 Q96HN2 Human SAHH-like domain of human adenosylhomocysteinase 3 HTML PDF
3GVU ABL2 + imatinib (Gleevec) P42684 The crystal structure of human ABL2 in complex with GLEEVEC HTML PDF
3H5Z LmNMT Q4Q5S8 Crystal Structure of Leishmania major N-myristoyltransferase with bound myristoyl-CoA HTML PDF
3H6N PLXND1 Q9Y4D7 Crystal Structure of the ubiquitin-like domain of plexin D1 HTML PDF
3H6O PKM2 P14618 Activator-Bound Structure of Human Pyruvate Kinase M2 HTML PDF
3H80 LmHSP90 Q4Q4I6 Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LmjF33.0312:M1-K213 HTML PDF
3H8H RNF2 Q99496 Structure of the C-terminal domain of human RNF2/RING1B; HTML PDF
3H8M EPHA7 Q15375 SAM domain of human ephrin type-a receptor 7 (EPHA7) HTML PDF
3H8Q TXNRD3 Q86VQ6 Crystal structure of glutaredoxin domain of human thioredoxin reductase 3 HTML PDF
3H8V UBA05 Q9GZZ9 Human Ubiquitin-activating Enzyme 5 in Complex with ATP HTML PDF
3H8Z FXR2 P51116 The Crystal Structure of the Tudor Domains from FXR2 HTML PDF
3H91 CBX2 Q14781, Q92133 Crystal structure of the complex of human chromobox homolog 2 (CBX2) and H3K27 peptide HTML PDF
3H95 NUDT6 P53370 Crystal structure of the NUDIX domain of NUDT6 HTML PDF
3H9E GAPDHS O14556 Crystal structure of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase (GAPDS) complex with NAD and phosphate HTML PDF
3H9F TTK + pyrimido-diazepin ligand P33981 Crystal Structure of Human Dual Specificity Protein Kinase (TTK) in complex with a pyrimido-diazepin ligand HTML PDF
3H9R ACVR1 + FKBP12 + dorsomorphin Q04771, P62942 Crystal structure of the kinase domain of type I activin receptor (ACVR1) in complex with FKBP12 and dorsomorphin HTML PDF
3H9U TBSAH Q383X0 S-adenosyl homocysteine hydrolase (SAHH) from Trypanosoma brucei HTML PDF
3HIL EPHA1 P21709 SAM Domain of Human Ephrin Type-A Receptor 1 (EphA1) HTML PDF
3HJC LmHSP90 Q4Q4I6 Crystal structure of the carboxy-terminal domain of HSP90 from Leishmania major, LmjF33.0312 HTML PDF
3HKO CpCDPK4-Pk (cgd7_40) Q5CZ29 Crystal structure of a cdpk kinase domain from cryptosporidium Parvum, cgd7_40 HTML PDF
3HKV PARP10 Q53GL7 Human poly(ADP-ribose) polymerase 10, catalytic fragment in complex with an inhibitor 3-aminobenzamide HTML PDF
3HLT HDHD2 Q9H0R4 The crystal structure of human haloacid dehalogenase-like hydrolase domain containing 2 (HDHD2) HTML PDF
3HM5 DMAP1 Q9NPF5 SANT domain of human DNA methyltransferase 1 associated protein 1 HTML PDF
3HM6 PLXNB1 O43157 Crystal structure of the cytoplasmic domain of human plexin B1 HTML PDF
3HM8 HK3 P52790 Crystal structure of the C-terminal Hexokinase domain of human HK3 HTML PDF
3HME BRD9 Q9H8M2 Crystal structure of human bromodomain containing 9 isoform 1 (BRD9) HTML PDF
3HMF PB1 Q86U86 Crystal Structure of the second Bromodomain of Human Poly-bromodomain containing protein 1 (PB1) HTML PDF
3HMH TAF1L Q8IZX4 Crystal structure of the second bromodomain of human TBP-associated factor RNA polymerase 1-like (TAF1L) HTML PDF
3HMI ABL2 + K00546 P42684 The crystal structure of human ABL2 in complex with 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE HTML PDF
3HN9 (superseded by 3UMN) LMNB1 P20700 Crystal Structure of Lamin-B1 HTML PDF
3HNA EHMT1 Q9H9B1 Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and mono-Methylated H3K9 Peptide HTML PDF
3HNG FLT1 (KINASE DOMAIN) P17948 Crystal structure of VEGFR1 in complex with N-(4-Chlorophenyl)-2-((pyridin-4-ylmethyl)amino)benzamide HTML PDF
3HX4 CDPK1 Q9BJF5 Crystal structure of CDPK1 of Toxoplasma gondii, TGME49_101440, in presence of calcium HTML PDF
3HZJ RABGAP1L Q5R372 Crystal structure of the RabGAP domain of the RABGAP1L protein HTML PDF
3HZT CDPK3 Q3HNM6 Crystal structure of Toxoplasma gondii CDPK3, TGME49_105860 HTML PDF
3I2B PTS Q03393 The crystal structure of human 6 Pyruvoyl Tetrahydrobiopterin Synthase HTML PDF
3I2N WDR92 Q96MX6 Crystal Structure of WD40 repeats protein WDR92 HTML PDF
3I2V MOCS3 O95396 Crystal structure of human MOCS3 rhodanese-like domain HTML PDF
3I33 HSPA2 P54652 Crystal structure of the human 70kDa heat shock protein 2 (Hsp70-2) ATPase domain in complex with ADP and inorganic phosphate HTML PDF
3I35 LASP1 Q14847 Human SH3 domain of protein LASP1 HTML PDF
3I3C CBX5 P45973 Crystal Structural of CBX5 Chromo Shadow Domain HTML PDF
3I3J EP300 (bromodomain) Q09472 Crystal Structure of the Bromodomain of Human EP300 HTML PDF
3I3K (superseded by 3LD6) CYP51A1 Q16850 Crystal structure of human lanosterol 14alpha-demethylase (CYP51) in complex with ketoconazole HTML PDF
3I3N KLHL11 Q9NVR0 Crystal structure of the BTB-BACK domains of human KLHL11 HTML PDF
3I3T USP21 Q9UK80, P62987 Crystal structure of covalent ubiquitin-USP21 complex HTML PDF
3IAR ADA P00813 The crystal structure of human adenosine deaminase HTML PDF
3ICU RNF128 Q8TEB7 Protease-associated domain of the E3 ligase grail HTML PDF
3IED HSP90 Q8IL32 Crystal structure of N-terminal domain of Plasmodium falciparum Hsp90 (PF14_0417) in complex with AMPPN HTML PDF
3IEZ IQGAP2 Q13576 Crystal structure of the RasGAP C-terminal (RGC) domain of IQGAP2 HTML PDF
3IGO CDPK1 A3FQ16 Crystal structure of Cryptosporidium parvum CDPK1, cgd3_920 HTML PDF
3IHJ GPT2 Q8TD30 Human alanine aminotransferase 2 in complex with PLP HTML PDF
3IHL CTPS2 Q9NRF8 Human CTPS2 crystal structure HTML PDF
3IHO MBD4 O95243 The C-terminal glycosylase domain of human MBD4 HTML PDF
3IHP USP05 P45974, P0CG48 Covalent Ubiquitin-Usp5 Complex HTML PDF
3IHW CENTG3 Q96P47 Crystal structure of the Ras-like domain of CENTG3 HTML PDF
3IHX PRDM10 Q9NQV6 Methyltransferase domain of human PR domain-containing protein 10 HTML PDF
3IHY PIK3C3 Q8NEB9 Human PIK3C3 crystal structure HTML PDF
3II0 GOT1 P17174 Crystal structure of human Glutamate oxaloacetate transaminase 1 (GOT1) HTML PDF
3II7 KLHL7 Q8IXQ5 Crystal structure of the kelch domain of human KLHL7 HTML PDF
3IQ2 SNX7 Q9UNH6 Human sorting nexin 7, phox homology (PX) domain HTML PDF
3IQ7 GSG2 + K00224 Q8TF76 Crystal Structure of human Haspin in complex with 5-Iodotubercidin HTML PDF
3IR3 HTD2 P86397 Crystal structure of human 3-hydroxyacyl-thioester dehydratase 2 (HTD2) HTML PDF
3IS5 CDPK6 B6KS23 Crystal structure of CDPK kinase domain from toxoplasma Gondii, TGME49_018720 HTML PDF
3ISQ HPD P32754 Crystal structure of human 4-Hydroxyphenylpyruvate dioxygenase HTML PDF
3ISU IQGAP3 Q86VI3 Crystal structure of the RGC domain of IQGAP3 HTML PDF
3ITK UGDH O60701 Crystal structure of human UDP-glucose dehydrogenase Thr131Ala, apo form. HTML PDF
3IU2 NMT1 P30419 Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD90096 HTML PDF
3IU5 PB1 Q86U86 Crystal structure of the first bromodomain of human poly-bromodomain containing protein 1 (PB1) HTML PDF
3IU6 PB1 Q86U86 Crystal structure of the sixth bromodomain of human poly-bromodomain containing protein 1 (PB1) HTML PDF
3IUC HSPA5 P11021 Crystal structure of the human 70kDa heat shock protein 5 (BiP/GRP78) ATPase domain in complex with ADP HTML PDF
3IUF DPF2 Q92785 Crystal structure of the C2H2-type zinc finger domain of human ubi-d4 HTML PDF
3IUG RICS A7KAX9 Crystal structure of the RhoGAP domain of RICS HTML PDF
3IUY DDX53 Q86TM3 Crystal structure of DDX53 DEAD-box domain HTML PDF
3IV1 TSG101 Q99816 Coiled-coil domain of tumor susceptibility gene 101 HTML PDF
3IWE NMT1 P30419 Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD85646 HTML PDF
3JPV PIM1 + Pyrrolo-[2-3]carbazole P11309 Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a pyrrolo[2,3-a]carbazole ligand HTML PDF
3JPX EED O75530, P62805 EED: A Novel Histone Trimethyllysine Binder Within The EED-EZH2 Polycomb Complex HTML PDF
3JWP SIR2A Q8IE47 Crystal structure of Plasmodium falciparum SIR2A (PF13_0152) in complex with AMP HTML PDF
3JYH DPP7 Q9UHL4 Human dipeptidyl peptidase DPP7 HTML PDF
3JYU USP04 P35123 Crystal structure of the N-terminal domains of the ubiquitin specific peptidase 4 (USP4) HTML PDF
3JZY ITSN2 Q9NZM3 Crystal structure of human Intersectin 2 C2 domain HTML PDF
3K0W MALT1 Q9UDY8 Crystal structure of the tandem IG-like C2-type 2 domains of the human mucosa-associated lymphoid tissue lymphoma translocation protein 1 HTML PDF
3K1Z HDHD3 Q9BSH5 Crystal Structure of Human Haloacid Dehalogenase-like Hydrolase Domain containing 3 (HDHD3) HTML PDF
3K21 CDPK3 Q9NJU9 Crystal Structure of carboxy-terminus of PFC0420w. HTML PDF
3K2I ACOT4 Q8N9L9 Human Acyl-coenzyme A thioesterase 4 HTML PDF
3K2J PB1 Q86U86 Crystal Structure of the 3rd Bromodomain of Human Poly-bromodomain containing protein 1 (PB1) HTML PDF
3K2L DYRK2 Q92630 Crystal Structure of dual-specificity tyrosine phosphorylation regulated kinase 2 (DYRK2) HTML PDF
3K2O PTDSR Q6NYC1 Structure of an oxygenase HTML PDF
3K35 SIRT6 Q8N6T7 Crystal Structure of Human SIRT6 HTML PDF
3K5K EHMT2 Q96KQ7 Discovery of a 2,4-Diamino-7-aminoalkoxy-quinazoline as a Potent Inhibitor of Histone Lysine Methyltransferase, G9a HTML PDF
3KCI HERC2 O95714 The third RLD domain of HERC2 HTML PDF
3KCZ PARP2 Q9UGN5 Human poly(ADP-ribose) polymerase 2, catalytic fragment in complex with an inhibitor 3-aminobenzamide HTML PDF
3KFV TJP3 O95049 Crystal structure of the SH3-kinase fragment of tight junction protein 3 (TJP3) in apo-form HTML PDF
3KH0 RALGDS Q12967 Crystal structure of the Ras-association (RA) domain of RALGDS HTML PDF
3KH6 (superseded by 3V2B) PARP15 (macro domain) Q460N3 Human poly(adp-ribose) polymerase 15 (ARTD7, BAL3), macro domain 2 in complex with adenosine-5-diphosphoribose HTML PDF
3KHD PYRK1 C6KTA4 Crystal Structure of PFF1300w. HTML PDF
3KHE CDPK3 Q3HNM6 Crystal structure of the calcium-loaded calmodulin-like domain of the CDPK, 541.m00134 from toxoplasma gondii HTML PDF
3KHF MAST3 (PDZ domain) O60307 The crystal structure of the PDZ domain of human Microtubule Associated Serine/Threonine Kinase 3 (MAST3) HTML PDF
3KHU UGDH + S00790a O60701 Crystal structure of human UDP-glucose dehydrogenase Glu161Gln, in complex with thiohemiacetal intermediate HTML PDF
3KJD PARP2 + ABT888 Q9UGN5 Human poly(ADP-ribose) polymerase 2, catalytic fragment in complex with an inhibitor ABT-888 HTML PDF
3KKA EPHA1 EPHA2 P21709, P29317 Co-crystal structure of the sam domains of EPHA1 AND EPHA2 HTML PDF
3KR7 Tankyrase-2 Q9H2K2 Human tankyrase 2 - catalytic PARP domain HTML PDF
3KR8 Tankyrase-2 + XAV939 Q9H2K2 Human tankyrase 2 - catalytic PARP domain in complex with an inhibitor XAV939 HTML PDF
3KS9 GRM1 + LY341495 Q13255 Metabotropic glutamate receptor mGluR1 complexed with LY341495 antagonist HTML PDF
3KU2 TgCDPK1 Q9BJF5 Crystal Structure of inactivated form of CDPK1 from toxoplasma gondii, TGME49.101440 HTML PDF
3KUF FXR1 P51114 The Crystal Structure of the Tudor Domains from FXR1 HTML PDF
3KUL EPHA8 P29322 Kinase domain of human ephrin type-A receptor 8 (EPHA8) HTML PDF
3KUP CBX3 Q13185 Crystal Structure of the CBX3 Chromo Shadow Domain HTML PDF
3KUQ DLC1 Q96QB1 Crystal structure of the DLC1 RhoGAP domain HTML PDF
3KUZ PLXNC1 O60486 Crystal structure of the ubiquitin like domain of PLXNC1 HTML PDF
3KVG CpHSP70 Q5CPP8 Crystal structure of the N-terminal domain of Hsp70 (cgd2_20) from Cryptosporidium parvum in complex with AMPPNP HTML PDF
3KVH NUDT16L1 Q9BRJ7 Crystal structure of human protein syndesmos (NUDT16-like protein) HTML PDF
3KVO SDHL Q6YN16 Crystal structure of the catalytic domain of human Hydroxysteroid dehydrogenase like 2 (HSDL2) HTML PDF
3KVW DYRK2 + indirubin Q92630 Crystal Structure of dual-specificity tyrosine phosphorylation regulated kinase 2 (DYRK2) in complex with an indirubin ligand HTML PDF
3L11 RNF168 Q8IYW5 Crystal Structure of the Ring Domain of RNF168 HTML PDF
3L19 CpCDPK3 Q5CS01 Crystal structure of calcium binding domain of CpCDPK3, cgd5_820 HTML PDF
3L42 BRPF1 P55201 PWWP domain of human bromodomain and PHD finger containing protein 1 HTML PDF
3L43 DNM3 Q9UQ16 Crystal structure of the dynamin 3 GTPase domain bound with GDP HTML PDF
3L46 ECT2 Q9H8V3 Crystal structure of the second BRCT domain of epithelial cell transforming 2 (ECT2) HTML PDF
3L4H HECW1 Q76N89 Helical box domain and second WW domain of the human E3 ubiquitin-protein ligase HECW1 HTML PDF
3L4I CpHSP70 Q5CPP8 CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HSP70 (CGD2_20) FROM Cryptosporidium PARVUM IN COMPLEX WITH ADP and inorganic phosphate HTML PDF
3L50 GMFG O60234 The crystal structure of human Glia Maturation Factor, Gamma (GMFG) HTML PDF
3L5K HDHD1A Q08623 The crystal structure of human Haloacid Dehalogenase-like Hydrolase Domain containing 1A (HDHD1A) HTML PDF
3L6Q CpHSP70 Q5CPP8 Crystal structure of the N-terminal domain of HSP70 from Cryptosporidium parvum (CGD2_20) HTML PDF
3L6S (superseded by 4DYO) DNPEP Q9ULA0 Crystal Structure of Human Aspartyl Aminopeptidase (DNPEP) in complex with Aspartic acid Hydroxamate HTML PDF
3LIJ CpCDPK3 Q5CS01 Crystal structure of full length CpCDPK3 (cgd5_820) in complex with Ca2+ and AMPPNP HTML PDF
3LJU CENTA1 O75689 Crystal structure of full length centaurin alpha-1 bound with the head group of PIP3 HTML PDF
3LLM DHX9 Q08211 Crystal Structure Analysis of a RNA Helicase HTML PDF
3LLR DNMT3A Q9Y6K1 Crystal structure of the PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 alpha HTML PDF
3LLT LAMMER Q8IL19 Crystal structure of PF14_0431, kinase domain. HTML PDF
3LLU RRAGC Q9HB90 Crystal structure of the nucleotide-binding domain of Ras-related GTP-binding protein C HTML PDF
3LM0 STK17B + ASC68 O94768 Crystal Structure of human Serine/Threonine Kinase 17B (STK17B) HTML PDF
3LM5 STK17B + Quercetin O94768 Crystal Structure of human Serine/Threonine Kinase 17B (STK17B) in complex with Quercetin HTML PDF
3LMK GRM5 P41594 Ligand Binding Domain of Metabotropoc glutamate receptor mGluR5 complexed with glutamate HTML PDF
3LMN USP15 Q9Y4E8 Oligomeric structure of the DUSP domain of human USP15 HTML PDF
3LS8 PIK3C3 Q8NEB9 Crystal structure of human PIK3C3 in complex with 3-[4-(4-Morpholinyl)thieno[3,2-d]pyrimidin-2-yl]-phenol HTML PDF
3LWE MPHOSPH8 Q99549 The crystal structure of MPP8 HTML PDF
3LWK CRYBA4 P53673 Crystal structure of human Beta-crystallin A4 (CRYBA4) HTML PDF
3LX7 CCDC101 Q96ES7 Crystal structure of a Novel Tudor domain-containing protein SGF29 HTML PDF
3LXJ KIAA1240 Q9ULI0 Crystal Structure of the Bromodomain of Human AAA domain containing 2B (ATAD2B) HTML PDF
3LXW (superseded by 3V70) GIMAP1 Q8WWP7 Crystal Structure of Human GTPase IMAP family member 1 HTML PDF
3LXX GIMAP4 Q9NUV9 Crystal structure of human GTPase IMAP family member 4 HTML PDF
3LY5 DDX18 Q9NVP1 DDX18 dead-domain HTML PDF
3LYI BRD1 O95696 PWWP Domain of Human Bromodomain-Containing Protein 1 HTML PDF
3LYR EBF1 Q9UH73 Human Early B-cell Factor 1 (EBF1) DNA-binding domain HTML PDF
3MA3 PIM1 + consensus peptide + naphtho-difuran ligand P11309 Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a naphtho-difuran ligand HTML PDF
3MAO SEPX1 Q9NZV6 Crystal Structure of Human Methionine-R-Sulfoxide Reductase B1 (MsrB1) HTML PDF
3MB3 PHIP Q8WWQ0 Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) HTML PDF
3MB4 PB1 + NMP Q86U86 Crystal Structure of the fifth Bromodomain of Human Poly-bromodomain containing protein 1 (PB1) with NMP HTML PDF
3MBW EPHA2 EPHA1 P29317, P20827 Crystal structure of the human ephrin A2 LBD and CRD domains in complex with ephrin A1 HTML PDF
3MCF NUDT10 Q8NFP7 Crystal structure of human diphosphoinositol polyphosphate phosphohydrolase 3-alpha HTML PDF
3MDY BMPR1B + FKBP12 + LDN-193189 O00238, P62942 Crystal structure of the cytoplasmic domain of the bone morphogenetic protein receptor type-1B (BMPR1B) in complex with FKBP12 and LDN-193189 HTML PDF
3MDZ CA7 P43166 Crystal Structure of Human Carbonic Anhydrase VII [isoform 1], CA7 HTML PDF
3ME3 PKM2 P14618 Activator-Bound Structure of Human Pyruvate Kinase M2 HTML PDF
3ME9 CCDC101 Q96ES7, Q92133 Crystal structure of SGF29 in complex with H3K4me3 peptide HTML PDF
3MEA CCDC101 Q96ES7, Q92133 Crystal structure of the SGF29 in complex with H3K4me3 HTML PDF
3MEK SMYD3 Q9H7B4 Crystal Structure of Human Histone-Lysine N-methyltransferase SMYD3 in Complex with S-adenosyl-L-methionine HTML PDF
3MET CCDC101 Q96ES7, Q92133 Crystal structure of SGF29 in complex with H3K4me2 HTML PDF
3MEU CCDC101 Q96ES7, Q92133 Crystal structure of SGF29 in complex with H3R2me2sK4me3 HTML PDF
3MEV CCDC101 Q96ES7, Q92133 Crystal structure of SGF29 in complex with R2AK4me3 HTML PDF
3MEW CCDC101 Q96ES7 Crystal structure of Novel Tudor domain-containing protein SGF29 HTML PDF
3MHJ TNKS2 Q9H2K2 Human tankyrase 2 - catalytic PARP domain in complex with 1-methyl-3-(trifluoromethyl)-5h-benzo[c][1,8]naphtyridine-6-one HTML PDF
3MHK TNKS2 Q9H2K2 Human tankyrase 2 - catalytic PARP domain in complex with 2-(2-pyridyl)-7,8-dihydro-5h-thiino[4,3-d]pyrimidin-4-ol HTML PDF
3MO8 BRPF1 P55201, Q16695 PWWP Domain of Human Bromodomain and PHD finger-containing protein 1 In Complex with Trimethylated H3K36 Peptide HTML PDF
3MOV (superseded by 3TYY) LMNB1 P20700 Crystal Structure of Human Lamin-B1 Coil 2 Segment HTML PDF
3MPX FGD5 Q6ZNL6 Crystal structure of the DH and PH-1 domains of human FGD5 HTML PDF
3MQ4 GRM7 Q14831 Metabotropic glutamate receptor mGluR7 complexed with LY341495 antagonist HTML PDF
3MQI EBF1 Q9UH73 Human early B-cell factor 1 (EBF1) IPT/TIG domain HTML PDF
3MQM ASH1L Q9NR48 Crystal Structure of the Bromodomain of human ASH1L HTML PDF
3MS5 BBOX1 O75936 Crystal Structure of Human gamma-butyrobetaine,2-oxoglutarate dioxygenase 1 (BBOX1) HTML PDF
3MSE CDPK6 Q8IID5 Crystal structure of C-terminal domain of PF110239. HTML PDF
3MTC INPP5B P32019 Crystal Structure of INPP5B in complex with phosphatidylinositol 4-phosphate HTML PDF
3MTF ACVR1 + 2-aminopyridine inhibitor Q04771 Crystal structure of the ACVR1 kinase in complex with a 2-aminopyridine inhibitor HTML PDF
3MTG AHCYL1 O43865 Crystal structure of human S-adenosyl homocysteine hydrolase-like 1 protein HTML PDF
3MTL PCTK1 + Indirubin E804 Q00536 Crystal structure of the PCTAIRE1 kinase in complex with Indirubin E804 HTML PDF
3MTN USP21 Q9UK80, P0CG48 Usp21 in complex with a ubiquitin-based, USP21-specific inhibitor HTML PDF
3MTS SUV39H1 O43463 Chromo Domain of Human Histone-Lysine N-Methyltransferase SUV39H1 HTML PDF
3MUJ EBF3 Q9H4W6 Early B-cell factor 3 (EBF3) IPT/TIG and dimerization helices HTML PDF
3MXF BRD4 bromodomain 1 + JQ1/SGCBD01 O60885 Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JQ1 HTML PDF
3MXO PGAM5 Q96HS1 Crystal structure oh human phosphoglycerate mutase family member 5 (PGAM5) HTML PDF
3MY0 ACVRL1 P37023 Crystal structure of the ACVRL1 (ALK1) kinase domain bound to LDN-193189 HTML PDF
3N0T DPP7 Q9UHL4 Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A HTML PDF
3N3K USP08 P40818, P0CG48 The catalytic domain of USP8 in complex with a USP8 specific inhibitor HTML PDF
3N50 EBF3 Q9H4W6 Human Early B-cell factor 3 (EBF3) IPT/TIG and HLHLH domains HTML PDF
3N72 Aha-1 Q689C6 Crystal Structure of Aha-1 from plasmodium falciparum, PFC0270w HTML PDF
3N8E HSPA9 P38646 Substrate binding domain of the human Heat Shock 70kDa protein 9 (mortalin) HTML PDF
3N9V INPP5B P32019 Crystal Structure of INPP5B HTML PDF
3N9X MAPK Q4Z5A3 Crystal structure of Map Kinase from plasmodium berghei, PB000659.00.0 HTML PDF
3N9Y CYP11A1 P05108, P10109 Crystal structure of human CYP11A1 in complex with cholesterol HTML PDF
3N9Z CYP11A1 P05108, P10109 Crystal structure of human CYP11A1 in complex with 22-hydroxycholesterol HTML PDF
3NA0 CYP11A1 P05108, P10109 Crystal structure of human CYP11A1 in complex with 20,22-dihydroxycholesterol HTML PDF
3NA3 (superseded by 4P7A) MLH1 P40692 Crystal Structure of human MLH1 HTML PDF
3NF1 KLC1 Q07866 Crystal structure of the TPR domain of kinesin light chain 1 HTML PDF
3NI8 Aha-1 Q689C4 Crystal Structure of PFC0360w, an HSP90 activator from plasmodium falciparum HTML PDF
3NIE MAPK2 Q7KQK7 Crystal Structure of PF11_0147 HTML PDF
3NR3 PMP2 P02689 Crystal Structure of Human Peripheral Myelin Protein 2 HTML PDF
3NR8 SHIP2 O15357 Crystal structure of human SHIP2 HTML PDF
3NR9 CLK2 P49760 Structure of human CDC2-like kinase 2 (CLK2) HTML PDF
3NRU EPHA7 Q15375 Ligand binding domain of EPHA7 HTML PDF
3NXB CECR2 Q9BXF3 Crystal Structure of the Bromodomain of human CECR2 HTML PDF
3O0T PGAM5 Q96HS1 Crystal structure of human phosphoglycerate mutase family member 5 (PGAM5) in complex with phosphate HTML PDF
3O2G BBOX1 O75936 Crystal Structure of Human gamma-butyrobetaine,2-oxoglutarate dioxygenase 1 (BBOX1) HTML PDF
3O46 MPP7 Q5T2T1 Crystal structure of the PDZ domain of MPP7 HTML PDF
3O47 ARFGAP1 P84077, Q8N6T3 Crystal structure of ARFGAP1-ARF1 fusion protein HTML PDF
3O4R DHRS4 Q9BTZ2 Crystal Structure of Human Dehydrogenase/Reductase (SDR family) member 4 (DHRS4) HTML PDF
3O70 PHF13 Q86YI8 PHD-type zinc finger of human PHD finger protein 13 HTML PDF
3O7A PHF13 Q86YI8, Q92133 Crystal structure of PHF13 in complex with H3K4me3 HTML PDF
3OLH MPST P25325 Human 3-mercaptopyruvate sulfurtransferase HTML PDF
3OLN UHRF2 Q96PU4 Crystal structure of the SRA domain of E3 ubiquitin-protein ligase UHRF2 HTML PDF
3OMC SND1 Q7KZF4 Structure of human SND1 extended tudor domain in complex with the symmetrically dimethylated arginine PIWIL1 peptide R4me2s HTML PDF
3OMG SND1 Q7KZF4 Structure of human SND1 extended tudor domain in complex with the symmetrically dimethylated arginine PIWIL1 peptide R14me2s HTML PDF
3OMU HSP90 Q389P1 Crystal Structure of the N-terminal domain of an HSP90 from Trypanosoma Brucei, Tb10.26.1080 in the presence of a thienopyrimidine derivative HTML PDF
3ONI BRD2 (bromodomain 2) + JQ1/SGCBD01 P25440 Crystal Structure of the second bromodomain of human BRD2 in complex with the inhibitor JQ1 HTML PDF
3OOM ACVR1 + K00507 Q04771 Crystal structure of the ACVR1 kinase domain in complex with the imidazo[1,2-b]pyridazine inhibitor K00507 HTML PDF
3OOY TKT P29401 Crystal structure of human Transketolase (TKT) HTML PDF
3OP0 Cbl-c + EGFR pY1069 peptide Q9ULV8, P00533 Crystal structure of Cbl-c (Cbl-3) TKB domain in complex with EGFR pY1069 peptide HTML PDF
3OP3 CDC25C P30307 Crystal Structure of Cell Division Cycle 25C Protein Isoform A from Homo sapiens HTML PDF
3OP5 VRK1 Q99986 Human vaccinia-related kinase 1 HTML PDF
3OPD HSP90 P12861 Crystal Structure of the N-terminal domain of an HSP90 from Trypanosoma Brucei, Tb10.26.1080 in the presence of a benzamide derivative HTML PDF
3OW8 WDR61 Q9GZS3 Crystal Structure of the WD repeat-containing protein 61 HTML PDF
3P0C NISCH Q9Y2I1 Nischarin PX-domain HTML PDF
3P0N TNKS2 Q9H2K2 Human Tankyrase 2 - Catalytic PARP domain in complex with an inhibitor HTML PDF
3P0P TNKS2 Q9H2K2 Human Tankyrase 2 - Catalytic PARP domain in complex with an inhibitor HTML PDF
3P0Q TNKS2 Q9H2K2 Human Tankyrase 2 - Catalytic PARP domain in complex with an inhibitor HTML PDF
3P1A PKMYT1 Q99640 Structure of human Membrane-associated Tyrosine- and Threonine-specific cdc2-inhibitory kinase MYT1 (PKMYT1) HTML PDF
3P1C CREBBP + acetylated lysine Q92793 Crystal structure of the bromodomain of human CREBBP in complex with acetylated lysine HTML PDF
3P1D CREBBP + NMP Q92793 Crystal structure of the bromodomain of human CREBBP in complex with N-Methyl-2-pyrrolidone (NMP) HTML PDF
3P1E CREBBP + DMSO Q92793 Crystal structure of the bromodomain of human CREBBP in complex with dimethyl sulfoxide (DMSO) HTML PDF
3P1F CREBBP + hydroquinazolin Q92793 Crystal structure of the bromodomain of human CREBBP in complex with a hydroquinazolin ligand HTML PDF
3P1I EPHB3 P54753 Ligand binding domain of human ephrin type-B receptor 3 HTML PDF
3P1J GIMAP2 Q9UG22 Crystal structure of human GTPase IMAP family member 2 in the nucleotide-free state HTML PDF
3P1M FDX1 +Fe-S cluster P10109 Crystal structure of human ferredoxin-1 (FDX1) in complex with iron-sulfur cluster HTML PDF
3P1W RABGDI Q8I501 Crystal Structure of RAB GDI from Plasmodium Falciparum, PFL2060c HTML PDF
3PFS BRPF3 Q9ULD4 PWWP Domain of Human Bromodomain and PHD finger-containing protein 3 HTML PDF
3PFV CBLB + EGFR pY1069 peptide Q13191, P00533 Crystal structure of Cbl-b TKB domain in complex with EGFR pY1069 peptide HTML PDF
3PFW GAPDHS O14556 Crystal structure of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase (GAPDS) complex with NAD, a binary form HTML PDF
3PFY OTUD5 Q96G74 The catalytic domain of human OTUD5 HTML PDF
3PG6 DTX3L Q8TDB6 The carboxyl terminal domain of human deltex 3-like HTML PDF
3PMI MUM1 Q2TAK8 PWWP Domain of Human Mutated Melanoma-Associated Antigen 1 HTML PDF
3PMT TDRD3 Q9H7E2 Crystal structure of the Tudor domain of human Tudor domain-containing protein 3 HTML PDF
3PP2 ARHGAP27 Q6ZUM4 Crystal structure of the pleckstrin homology domain of ArhGAP27 HTML PDF
3PPA USP15 Q9Y4E8 Structure of the Dusp-Ubl domains of Usp15 HTML PDF
3PRY HSP90B1 (middle domain) P08238 Crystal structure of the middle domain of human HSP90-beta refined at 2.3 A resolution HTML PDF
3PS4 MAST1 (PDZ domain) Q9Y2H9 PDZ domain from Human microtubule-associated serine/threonine-protein kinase 1 HTML PDF
3Q1D TRIM54 Q9BYV2 The B-box domain of Trim54 HTML PDF
3Q1J PHF20 Q9BVI0 Crystal structure of tudor domain 1 of human PHD finger protein 20 HTML PDF
3Q2E WDR9 Q9NSI6 Crystal structure of the second bromodomain of human bromodomain and WD repeat-containing protein 1 isoform A (WDR9) HTML PDF
3Q2F BAZ2 Q9UIF8 Crystal Structure of the bromodomain of human BAZ2B in complex with a triazolo ligand HTML PDF
3Q3J PLXNA2 + RND1 O75051, Q92730 Crystal structure of plexin A2 RBD in complex with Rnd1 HTML PDF
3Q4S GYG1 P46976 Crystal Structure of Human Glycogenin-1 (GYG1), apo form HTML PDF
3Q4T ACVR2 P27037 Crystal structure of Activin receptor type-IIA (ACVR2A) kinase domain in complex with dorsomorphin HTML PDF
3Q4U ACVR1 Q04771 Crystal structure of the ACVR1 kinase domain in complex with LDN-193189 HTML PDF
3Q71 PARP14 Q460N5 Human parp14 (artd8) - macro domain 2 in complex with adenosine-5-diphosphoribose HTML PDF
3QBY HDGF2 Q7Z4V5, P62805 Crystal structure of the PWWP domain of human Hepatoma-derived growth factor 2 HTML PDF
3QF9 PIM1 P11309 Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a furan-thiazolidinedione ligand HTML PDF
3QII PHF20 Q9BVI0 Crystal structure of tudor domain 2 of human PHD finger protein 20 HTML PDF
3QIK PREX1 Q8TCU6 Crystal structure of the first PDZ domain of PREX1 HTML PDF
3QIR PIWIL2 Q8TC59 Crystal structure of PIWIL2 PAZ domain HTML PDF
3QJ6 HDGF2 Q7Z4V5, P68431 The crystal structure of PWWP domain of human Hepatoma-derived growth factor 2 in complex with H3K79me3 peptide HTML PDF
3QK3 CRYBB3 P26998 Crystal structure of human beta-crystallin B3 HTML PDF
3QKJ DNMT3B Q9UBC3 The PWWP domain of human DNA (CYTOSINE-5-)-METHYLTRANSFERASE 3 BETA in complex with a bis-tris molecule HTML PDF
3QMB CXXC1 Q9P0U4 Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1 HTML PDF
3QMC CXXC1 Q9P0U4 Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1 HTML PDF
3QMD CXXC1 Q9P0U4 Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1 HTML PDF
3QMG CXXC1 Q9P0U4 Structural Basis of Selective Binding of Non-Methylated CpG islands by the CXXC Domain of CFP1 HTML PDF
3QMH CXXC1 Q9P0U4 Structural Basis of Selective Binding of Non-Methylated CpG islands (DNA-TCGA) by the CXXC Domain of CFP1 HTML PDF
3QMI CXXC1 Q9P0U4 Structural Basis of Selective Binding of Non-Methylated CpG islands (DNA-ACGT) by the CXXC Domain of CFP1 HTML PDF
3QNF ERAP1 Q9NZ08 Crystal structure of the open state of human endoplasmic reticulum aminopeptidase 1 ERAP1 HTML PDF
3QVB GYG1 + UDP P46976 Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and UDP HTML PDF
3QVE HBP1 O60381 Crystal structure of human HMG box-containing protein 1, HBP1 HTML PDF
3QWE GMIP Q9P107 Crystal structure of the N-terminal domain of the GEM interacting protein HTML PDF
3QWL TBC1D7 Q9P0N9 Crystal structure of human TBC1 domain family member 7 HTML PDF
3QWM IQSEC1 Q6DN90 Crystal Structure of GEP100, the plextrin homology domain of IQ motif and SEC7 domain-containing protein 1 isoform a HTML PDF
3QWP SMYD3 Q9H7B4 Crystal structure of SET and MYND domain containing 3; Zinc finger MYND domain-containing protein 1 HTML PDF
3R90 MCTS1 Q9ULC4 Crystal structure of Malignant T cell-amplified sequence 1 protein HTML PDF
3RAW CLK3 P49761 Crystal Structure of human CDC-like kinase 3 isoform in complex with leucettine L41 HTML PDF
3RAY PRMD11 Q9NQV5 Crystal structure of Methyltransferase domain of human PR domain-containing protein 11 HTML PDF
3RBN MLH1 P40692 Crystal structure of MutL protein homolog 1 isoform 1 [Homo sapiens] HTML PDF
3RCO TDRD7 Q8NHU6 Crystal structure of a conserved motif in human TDRD7 HTML PDF
3RCQ (superseded by 5APA) ASPH Q12797 Crystal structure of human aspartate beta-hydroxylase isoform a HTML PDF
3RCW BRD1 O95696 Crystal Structure of the bromodomain of human BRD1 HTML PDF
3RJW EHMT2 Q96KQ7 Crystal structure of histone lysine methyltransferase g9a with an inhibitor HTML PDF
3RMU MCEE Q96PE7 Crystal structure of human Methylmalonyl-CoA epimerase, MCEE HTML PDF
3RMV GYG1 P46976 Crystal Structure of Human Glycogenin-1 (GYG1) T83M mutant complexed with manganese and UDP HTML PDF
3RMW GYG1 P46976 Crystal Structure of Human Glycogenin-1 (GYG1) T83M mutant complexed with manganese and UDP-glucose HTML PDF
3RNJ BAIAP2 Q9UQB8 Crystal structure of the SH3 domain from IRSp53 (BAIAP2) HTML PDF
3RPX C1QBP Q07021 Crystal structure of complement component 1, q subcomponent binding protein, C1QBP HTML PDF
3RQ4 SUV420H2 Q86Y97 Crystal structure of suppressor of variegation 4-20 homolog 2 HTML PDF
3S4Y TPK1 Q9H3S4 Crystal structure of human thiamin pyrophosphokinase 1 HTML PDF
3S6B PfMetAP1b Q8IJP2 Crystal structure of methionine aminopeptidase 1b from Plasmodium Falciparum, PF10_0150 HTML PDF
3S8I DDI1 Q8WTU0 The retroviral-like protease (RVP) domain of human DDI1 HTML PDF
3S8P SUV420H1 Q4FZB7 Crystal Structure of the SET Domain of Human Histone-Lysine N-Methyltransferase SUV420H1 In Complex With S-Adenosyl-L-Methionine HTML PDF
3S8S SETD1A O15047 Crystal structure of the RRM domain of human SETD1A HTML PDF
3S91 BRD3 Q15059 Crystal Structure of the first bromodomain of human BRD3 in complex with the inhibitor JQ1 HTML PDF
3S92 BRD3 Q15059 Crystal Structure of the second bromodomain of human BRD3 in complex with the inhibitor JQ1 HTML PDF
3S93 TDRD5 Q8NAT2 Crystal structure of conserved motif in TDRD5 HTML PDF
3S95 LIMK1 P53667 Crystal structure of the human LIMK1 kinase domain in complex with staurosporine HTML PDF
3SM9 GRM3 Q14832 Crystal Structure of Metabotropic glutamate receptor 3 precursor in presence of LY341495 antagonist HTML PDF
3SMP PANK1 Q8TE04 Monoclinic crystal structure of human pantothenate kinase 1 alpha HTML PDF
3SMQ PRMT3 O60678 Crystal structure of protein arginine methyltransferase 3 HTML PDF
3SMR WDR5 P61964 Crystal structure of human WD repeat domain 5 with compound HTML PDF
3SMS PANK3 Q9H999 Human Pantothenate kinase 3 in complex with a pantothenate analog HTML PDF
3SMT SETD3 Q86TU7 Crystal structure of human SET domain-containing protein3 HTML PDF
3SMU (superseded by 3U7X) EIF4E P06730, Q13541 Crystal structure of the human eIF4E-4EBP1 peptide complex without cap HTML PDF
3SO8 ANKRA2 Q9H9E1 Crystal Structure of ANKRA HTML PDF
3SOC ACVR2 P27037 Crystal structure of Activin receptor type-IIA (ACVR2A) kinase domain in complex with a quinazolin HTML PDF
3SOE MAGI3 Q5TCQ9 Crystal Structure of the 3rd PDZ domain of the human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (MAGI3) HTML PDF
3SOG AMPH P49418 Crystal structure of the BAR domain of human Amphiphysin, isoform 1 HTML PDF
3SOM MMACHC Q9Y4U1 crystal structure of human MMACHC HTML PDF
3SVH CREBBP Q92793 Crystal Structure of the bromdomain of human CREBBP in complex with a 3,5-dimethylisoxazol ligand HTML PDF
3SX0 DOT1L Q8TEK3 Crystal structure of Dot1l in complex with a brominated SAH analog HTML PDF
3T7L ZFYVE16 Q7Z3T8 Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution HTML PDF
3T7M GYG1 P46976 Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and UDP, in a triclinic closed form HTML PDF
3T7N GYG1 P46976 Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and UDP, in a monoclinic closed form HTML PDF
3T7O GYG1 P46976 Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP-Glucose and glucose HTML PDF
3TLP PB1 Q86U86 Crystal structure of the fourth bromodomain of human poly-bromodomain containing protein 1 (PB1) HTML PDF
3TLX Pf-AK Q8IJV6 Crystal Structure of PF10_0086, adenylate kinase from plasmodium falciparum HTML PDF
3TUG ITCH Q96J02 Crystal structure of the HECT domain of ITCH E3 ubiquitin ligase HTML PDF
3U23 CD2AP Q9Y5K6, Q8TB24 Atomic resolution crystal structure of the 2nd SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide from human RIN3 HTML PDF
3U2T GYG1 P46976 Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese HTML PDF
3U2U GYG1 P46976 Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP and maltotetraose HTML PDF
3U2V GYG1 P46976 Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP and maltohexaose HTML PDF
3U2W GYG1 P46976 Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and glucose or a glucal species HTML PDF
3U2X GYG1 P46976 Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP and 1'-deoxyglucose HTML PDF
3U2Z PKM2 P14618 Activator-Bound Structure of Human Pyruvate Kinase M2 HTML PDF
3UR4 WDR5 P61964 Crystal structure of human WD repeat domain 5 with compound HTML PDF
3UV2 FALZ Q12830 Crystal structure of the bromodomain of human nucleosome-remodeling factor subunit BPTF HTML PDF
3UV4 TAF1 P21675 Crystal Structure of the second bromodomain of human Transcription initiation factor TFIID subunit 1 (TAF1) HTML PDF
3UV5 TAF1 P21675 Crystal Structure of the tandem bromodomains of human Transcription initiation factor TFIID subunit 1 (TAF1) HTML PDF
3UVD SMARCA4 P51532 Crystal Structure of the bromodomain of human Transcription activator BRG1 (SMARCA4) in complex with N-Methyl-2-pyrrolidone HTML PDF
3UVJ XX13GUCY1A3 Q02108, Q02153 Crystal structure of the catalytic domain of the heterodimeric human soluble guanylate cyclase 1. HTML PDF
3UVW BRD4 O60885, P62805 Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H4K5acK8ac) HTML PDF
3UVX BRD4 O60885, P62805 Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H4K12acK16ac) HTML PDF
3UVY BRD4 O60885, P62805 Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H4K16acK20ac) HTML PDF
3UW9 BRD4 O60885, P62805 Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H4K8acK12ac) HTML PDF
3UWP DOT1L Q8TEK3 Crystal structure of Dot1l in complex with 5-iodotubercidin HTML PDF
3UXG RFXANK O14593, P56524 Crystal structure of RFXANK HTML PDF
3V2O ANKRA2 Q9H9E1, P98158 Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2 HTML PDF
3V2X ANKRA2 Q9H9E1, P98158 Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2 HTML PDF
3V30 RFXANK O14593, P48382 Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human RFXANK HTML PDF
3V31 ANKRA2 Q9H9E1, P56524 Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2 HTML PDF
3ZDQ ABCB10 Q9NRK6 STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (NUCLEOTIDE-FREE FORM) HTML PDF
3ZDU CDKL3 Q8IVW4 Crystal structure of the human CDKL3 kinase domain HTML PDF
3ZHP XX03CAB39L Q9H9S4, Q9Y6E0 Human MST3 (STK24) in complex with MO25beta HTML PDF
3ZI1 GLOD4 Q9HC38 Crystal structure of human glyoxalase domain-containing protein 4 (GLOD4) HTML PDF
3ZON TYK2 P29597 Human TYK2 pseudokinase domain bound to a kinase inhibitor HTML PDF
3ZOS DDR1 Q08345 Structure of the DDR1 kinase domain in complex with ponatinib HTML PDF
3ZP5 FEV Q99581 Crystal structure of the DNA binding ETS domain of the human protein FEV in complex with DNA HTML PDF
3ZW5 GLOD5 A6NK44 Crystal structure of the human Glyoxalase domain-containing protein 5 HTML PDF
3ZWF ELAC1 Q9H777 Crystal structure of Human tRNase Z, short form (ELAC1). HTML PDF
3ZYQ HGS O14964 Crystal structure of the tandem VHS and FYVE domains of Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS-Hrs) at 1.48 A resolution HTML PDF
3ZYW TXNL2 O76003 Crystal structure of the first glutaredoxin domain of human glutaredoxin 3 (GLRX3) HTML PDF
4A27 KIAA1576 Q9HCJ6 Crystal structure of human synaptic vesicle membrane protein VAT-1 homolog-like protein HTML PDF
4A35 ENOSF1 Q7L5Y1 Crystal structure of human Mitochondrial enolase superfamily member 1 (ENOSF1) HTML PDF
4A3A (superseded by 4ATM) AMPH P49418 Crystal structure of the BAR domain of human Amphiphysin, isoform 1 at 1.8 Angstrom resolution featuring increased order at the N- terminus. HTML PDF
4A60 FABP9 Q0Z7S8 Crystal structure of human testis-specific fatty acid binding protein 9 (FABP9) HTML PDF
4A63 XX01TP73 O15350, Q13625 Crystal structure of the p73-ASPP2 complex at 2.6A resolution HTML PDF
4A64 CUL4B Q13620 Crystal structure of the N-terminal domain of human Cul4B at 2.57A resolution HTML PDF
4A9Z TP73L Q9H3D4 CRYSTAL STRUCTURE OF HUMAN P63 TETRAMERIZATION DOMAIN HTML PDF
4AAA CDKL2 Q92772 Crystal structure of the human CDKL2 kinase domain HTML PDF
4AAP FLJ13798 Q8N371 Crystal structure of JMJD5 domain of human Lysine-specific demethylase 8 (KDM8) in complex with N-oxalylglycine (NOG) HTML PDF
4ABN TTC5MMA Q99LG4 Crystal structure of full length mouse Strap (TTC5) HTML PDF
4AD9 LACTB2 Q53H82 Crystal structure of human LACTB2. HTML PDF
4AF3 XX07AURKB Q96GD4, Q9NQS7 Human Aurora B Kinase in complex with INCENP and VX-680 HTML PDF
4AGU CDKL1 Q00532 CRYSTAL STRUCTURE OF THE HUMAN CDKL1 KINASE DOMAIN HTML PDF
4AKV SNX33 Q8WV41 Crystal structure of human sorting nexin 33 (SNX33) HTML PDF
4AOT STK10 O94804 Crystal Structure of Human Serine Threonine Kinase-10 (LOK) Bound to GW830263A HTML PDF
4AP2 XX06CUL3 Q9NVR0, Q13618 Crystal structure of the human KLHL11-Cul3 complex at 2.8A resolution HTML PDF
4AP8 MOCS2B O96007 Crystal structure of human Molybdopterin synthase catalytic subunit (MOCS2B) HTML PDF
4APC NEK1 Q96PY6 Crystal Structure of Human NIMA-related Kinase 1 (NEK1) HTML PDF
4APF XX01CUL3 Q9NVR0, Q13618 Crystal structure of the human KLHL11-Cul3 complex at 3.1A resolution HTML PDF
4ASC KBTBD5 Q2TBA0 Crystal structure of the Kelch domain of human KBTBD5 HTML PDF
4ASI ACACA Q13085 Crystal structure of human ACACA C-terminal domain HTML PDF
4ASX ACVR2 P27037 Crystal structure of Activin receptor type-IIA (ACVR2A) kinase domain in complex with dihydro-Bauerine C HTML PDF
4ATM AMPH P49418 Crystal structure of the BAR domain of human Amphiphysin, isoform 1 at 1.8 Angstrom resolution featuring increased order at the N- terminus. HTML PDF
4AVM BIN2 Q9UBW5 Crystal structure of the N-BAR domain of human bridging integrator 2. HTML PDF
4AVP ETV1 P50549 Crystal structure of the DNA-binding domain of human ETV1. HTML PDF
4AVX HGS O14964 Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate (Hgs-Hrs) bound to an IP2 compound at 1.68 A Resolution HTML PDF
4AW2 CDC42BPA O54874 Crystal structure of CDC42 binding protein kinase alpha (MRCK alpha) HTML PDF
4AW6 ZMPSTE24 O75844 Crystal structure of the human nuclear membrane zinc metalloprotease ZMPSTE24 (FACE1) HTML PDF
4AYT ABCB10 Q9NRK6 STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 HTML PDF
4AYW ABCB10 Q9NRK6 STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (PLATE FORM) HTML PDF
4AYX ABCB10 Q9NRK6 STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (ROD FORM B) HTML PDF
4AZ9 SNX24 Q9Y343 Crystal structure of phox homology domain of human sorting nexin 24 HTML PDF
4AZE DYRK1A Q13627 Human DYRK1A in complex with Leucettine L41 HTML PDF
4AZF DYRK2 Q92630 Human DYRK2 in complex with Leucettine L41 HTML PDF
4B06 (superseded by 4BNC) ETV1 P50549 Crystal structure of the DNA-binding domain of human ETV1 complexed with DNA HTML PDF
4B4C CHD1 O14646 Crystal structure of the DNA-binding domain of human CHD1. HTML PDF
4B4O C14ORF124 Q9NRG7 Crystal Structure of human epimerase family protein SDR39U1 (isoform2) with NADPH HTML PDF
4B87 DCLRE1A Q6PJP8 Crystal structure of human DNA cross-link repair 1A HTML PDF
4B8W TSTA3 Q13630 Crystal structure of human GDP-L-fucose synthase with bound NADP and GDP, tetragonal crystal form HTML PDF
4B8Z TSTA3 Q13630 Crystal structure of human GDP-L-fucose synthase with bound NADP and GDP, rhombohedral crystal form HTML PDF
4B99 MAPK7 Q13164 Crystal Structure of MAPK7 (ERK5) with inhibitor HTML PDF
4B9D NEK1 Q96PY6 Crystal Structure of Human NIMA-related Kinase 1 (NEK1) with inhibitor. HTML PDF
4BBM CDKL2 Q92772 CRYSTAL STRUCTURE OF THE HUMAN CDKL2 KINASE DOMAIN WITH BOUND TCS 2312 HTML PDF
4BC6 STK10 O94804 Crystal structure of human serine threonine kinase-10 bound to novel Bosutinib Isoform 1, previously thought to be Bosutinib HTML PDF
4BGG ACVR1 Q04771 Crystal structure of the ACVR1 kinase in complex with LDN-213844 HTML PDF
4BGJ SNX14 Q9Y5W7 Crystal structure of the phox-homology domain of human sorting nexin 14 HTML PDF
4BGQ CDKL5 O76039 Crystal structure of the human CDKL5 kinase domain HTML PDF
4BKJ DDR1A Q08345 Crystal structure of the human DDR1 kinase domain in complex with imatinib HTML PDF
4BKN DPYSL3 Q14195 Human Dihydropyrimidinase-related protein 3 (DPYSL3) HTML PDF
4BKP TSTA3 Q13630 Crystal structure of human GDP-L-fucose synthase with bound NADP HTML PDF
4BKW ZFYVE9C O95405 Crystal structure of the C-terminal region of human ZFYVE9 HTML PDF
4BL5 TSTA3 Q13630 Crystal structure of human GDP-L-fucose synthase with bound NADP and product GDP-L-fucose HTML PDF
4BNC ETV1 P50549 Crystal structure of the DNA-binding domain of human ETV1 complexed with DNA HTML PDF
4BQA ETS2 P15036 Crystal structure of the ETS domain of human ETS2 in complex with DNA HTML PDF
4BQM GLS2 Q9UI32 Crystal structure of human liver-type glutaminase, catalytic domain HTML PDF
4BW5 KCNK10 P57789 Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) HTML PDF
4BZY GBE1 Q04446 Crystal structure of human glycogen branching enzyme (GBE1) HTML PDF
4C02 ACVR1 Q04771, P68106 Crystal structure of human ACVR1 (ALK2) in complex with FKBP12.6 and dorsomorphin HTML PDF
4C45 PCBD2 Q9H0N5 Crystal structure of human pterin-4-alpha-carbinolamine dehydratase 2 (PCBD2) HTML PDF
4C8B RIPK2 O43353 Structure of the kinase domain of human RIPK2 in complex with ponatinib HTML PDF
4C8D JMJD1B Q7LBC6 Crystal structure of JmjC domain of human histone 3 Lysine-specific demethylase 3B (KDM3B) HTML PDF
4C9W NUDT1 P36639 Crystal structure of NUDT1 (MTH1) with R-crizotinib HTML PDF
4C9X NUDT1 P36639 Crystal structure of NUDT1 (MTH1) with S-crizotinib HTML PDF
4CCZ MTR Q99707 Crystal structure of human 5-methyltetrahydrofolate-homocysteine methyltransferase, the homocysteine and folate binding domains HTML PDF
4CDG BLM P54132 Crystal structure of the Bloom's syndrome helicase BLM in complex with Nanobody HTML PDF
4CGZ BLM P54132 Crystal structure of the Bloom's syndrome helicase BLM in complex with DNA HTML PDF
4CH9 KLHL3 Q9UH77, Q96J92 Crystal structure of the human KLHL3 Kelch domain in complex with a WNK4 peptide HTML PDF
4CHB KLHL2 O95198, Q96J92 Crystal structure of the human KLHL2 Kelch domain in complex with a WNK4 peptide HTML PDF
4CKR DDR1 Q08345 Crystal structure of the human DDR1 kinase domain in complex with DDR1-IN-1 HTML PDF
4CO8 ETV4 P43268 Structure of the DNA binding ETS domain of human ETV4 HTML PDF
4COO CBS P35520 Crystal structure of human cystathionine beta-synthase (delta516-525) at 2.0 angstrom resolution HTML PDF
4COS PRKCBP1 Q9ULU4 Crystal structure of the PHD-Bromo-PWWP cassette of human PRKCBP1 HTML PDF
4CRH SHKBP1 Q8TBC3 Crystal structure of the BTB-T1 domain of human SHKBP1 HTML PDF
4CRS PRKCL2 Q16513 Human Protein Kinase N2 (PKN2, PRKCL2) in complex with ATPgammaS HTML PDF
4CVH ISPD A4D126 Crystal structure of human isoprenoid synthase domain-containing protein HTML PDF
4CVO ERCC6 Q03468 Crystal structure of the N-terminal colied-coil domain of human DNA excision repair protein ERCC-6 HTML PDF
4CXA CDK12 Q9NYV4, O75909 Crystal structure of the human CDK12-cyclin K complex bound to AMPPNP HTML PDF
4D0N AKAP13 P61586, Q12802 AKAP13 (AKAP-Lbc) RhoGEF domain in complex with RhoA HTML PDF
4D0O AKAP13 Q12802 AKAP13 (AKAP-Lbc) DH domain HTML PDF
4DIP FKBP14 Q9NWM8 Crystal structure of human Peptidyl-prolyl cis-trans isomerase FKBP14 HTML PDF
4DIQ FLJ21802 Q9H6W3 Crystal Structure of human NO66 HTML PDF
4DO0 PHF8 Q9UPP1 Crystal Structure of human PHF8 in complex with Daminozide HTML PDF
4DYL FES P07332 F-BAR domain of human FES tyrosine kinase HTML PDF
4DYM ACVR1 Q04771 Crystal structure of the ACVR1 kinase domain in complex with the imidazo[1,2-b]pyridazine inhibitor K00135 HTML PDF
4E71 HTML PDF
4E74 HTML PDF
4E93 HTML PDF
4EFC ASL Q38EJ2 Crystal Structure of Adenylosuccinate Lyase from Trypanosoma Brucei, Tb427tmp.160.5560 HTML PDF
4EQZ DOT1L Q8TEK3 Crystal structure of human DOT1L in complex with inhibitor FED2 HTML PDF
4ER0 DOT1L Q8TEK3 Crystal Structure of human DOT1L in complex with inhibitor FED1 HTML PDF
4ER3 DOT1L Q8TEK3 Crystal Structure of Human DOT1L in complex with inhibitor EPZ004777 HTML PDF
4ER5 DOT1L Q8TEK3 Crystal structure of human DOT1L in complex with 2 molecules of EPZ004777 HTML PDF
4ER6 DOT1L Q8TEK3 Crystal structure of human DOT1L in complex with inhibitor SGC0946 HTML PDF
4ER7 DOT1L Q8TEK3 Crystal Structure of human DOT1L in complex with inhibitor SGC0947 HTML PDF
4FLA RPRD1B Q9NQG5 Crystal structure of human RPRD1B, carboxy-terminal domain HTML PDF
4FLB RPRD2 Q5VT52 CID of human RPRD2 HTML PDF
4FLD (superseded by 4HFG) RPRD1B Q9NQG5 CID of human RPRD1B HTML PDF
4FLP BRDT Q58F21 Crystal Structure of the first bromodomain of human BRDT in complex with the inhibitor JQ1 HTML PDF
4FMU SETD2 Q9BYW2 Crystal structure of Methyltransferase domain of human SET domain-containing protein 2 Compound: Pr-SNF HTML PDF
4FMW RG9MTD2 Q8TBZ6 Crystal structure of methyltransferase domain of human RNA (guanine-9-) methyltransferase domain containing protein 2 HTML PDF
4FO9 PIAS2 O75928 Crystal structure of the E3 SUMO Ligase PIAS2 HTML PDF
4FR4 YANK1 Q8WU08 Crystal structure of human serine/threonine-protein kinase 32A (YANK1) HTML PDF
4FU6 PSIPS1 O75475 Crystal structure of the PSIP1 PWWP domain HTML PDF
4FUK Tb-MetAP Q4FKC0 Aminopeptidase from Trypanosoma brucei HTML PDF
4GLM DNMBP Q6XZF7 Crystal structure of the SH3 Domain of DNMBP protein [Homo sapiens] HTML PDF
4GPJ BRD4 O60885 Crystal Structure of the first bromodomain of human BRD4 in complex with a isoxazolylbenzimidazole ligand HTML PDF
4GW8 PIM1 P11309 Human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and Leucettine L41 HTML PDF
4H12 SETD2 Q9BYW2 The crystal structure of methyltransferase domain of human SET domain-containing protein 2 in complex with S-adenosyl-L-homocysteine HTML PDF
4H4H (superseded by 4I51) EHMT1 P68431, Q9H9B1 Methyltransferase domain of HUMAN EUCHROMATIC HISTONE METHYLTRANSFERASE 1, mutant Y1211A HTML PDF
4HAE CDYL2 Q8N8U2 Crystal structure of the CDYL2-chromodomain HTML PDF
4HAS SNX27 Q96L92 Crystal structure of PX domain of human sorting nexin SNX27 HTML PDF
4HBD KANK2 Q63ZY3 Crystal structure of KANK2 ankyrin repeats HTML PDF
4HBV BRD4 O60885 Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazolin ligand HTML PDF
4HBW BRD4 O60885 Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazoline ligand HTML PDF
4HBX BRD4 O60885 Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazolin ligand HTML PDF
4HBY BRD4 O60885 Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazolin ligand HTML PDF
4HC4 PRMT6 Q96LA8 Human HMT1 hnRNP methyltransferase-like protein 6 (S. cerevisiae) HTML PDF
4HSG PRMT3 O60678 Crystal structure of human PRMT3 in complex with an allosteric inhibitor (PRMT3- KTD) HTML PDF
4I79 NUP43 Q8NFH3 Crystal structure of human NUP43 HTML PDF
4IA9 WDR5 P61964 Crystal structure of human WD REPEAT DOMAIN 5 in complex with 2-chloro-4-fluoro-3-methyl-N-[2-(4-methylpiperazin-1-yl)-5-nitrophenyl]benzamide HTML PDF
4IGZ (superseded by 5VEI) SORBS2 O94875 Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2 HTML PDF
4II1 ZGPAT Q8N5A5 Crystal structure of the zinc finger of ZGPAT HTML PDF
4IIM ITSN1 Q15811 Crystal structure of the Second SH3 Domain of ITSN1 bound with a synthetic peptide HTML PDF
4IIO ITSN2 Q9NZM3 Crystal Structure of the Second SH3 Domain of ITSN2 Bound with a Synthetic Peptide HTML PDF
4IJ8 SETD8 Q9NQR1 Crystal structure of the complex of SETD8 with SAM HTML PDF
4IJD PRDM9 Q9NQV7 Crystal structure of methyltransferase domain of human PR domain-containing protein 9 HTML PDF
4IKP CARM1 Q86X55 Crystal structure of coactivator-associated arginine methyltransferase 1 with methylenesinefungin HTML PDF
4J0R BRD4 O60885 Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand HTML PDF
4J0S BRD4 O60885 Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand HTML PDF
4J5M MYO5B Q9ULV0 Structure of the Cargo Binding Domain from Human Myosin Vb HTML PDF
4JDS SETD7 Q8WTS6 SETD7 in complex with inhibitor PF-5426 and S-adenosyl-methionine HTML PDF
4JLG SETD7 Q8WTS6 SETD7 in complex with inhibitor (R)-PFI-2 and S-adenosyl-methionine HTML PDF
4JUY RNF31 Q96EP0 Crystal structure of the PUB domain of E3 ubiquitin ligase RNF31 HTML PDF
4JXT RPRD1A Q96P16, P24928 CID of human RPRD1A in complex with a phosphorylated peptide from RPB1-CTD HTML PDF
4KFA FDPS P14324 Crystal structure of human farnesyl pyrophosphate synthase (t201a mutant) complexed with mg and zoledronate HTML PDF
4KPD FDPS P14324 Crystal Structure of Human Farnesyl Pyrophosphate Synthase (Y204F) Mutant Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate HTML PDF
4KPJ FDPS P14324 Crystal Structure of Farnesyl Pyrophosphate Synthase (Y204A) Mutant complexed with Mg, Pamidronate HTML PDF
4KQS FDPS P14324 Crystal Structure of Farnesyl Pyrophosphate Synthase Mutant (Y204A) Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate HTML PDF
4KQU FDPS P14324 Crystal Structure of Farnesyl Synthase Mutant (Y204A) Complexed with Mg, Alendronate and Isopentenyl Pyrophosphate HTML PDF
4L1M HERC2 O95714 Structure of the first RCC1-like domain of HERC2 HTML PDF
4LD6 PWWP2B Q6NUJ5 PWWP domain of human PWWP Domain-Containing Protein 2B HTML PDF
4LDF Cp-BRD2 Q5CUE2 Crystal Structure of CpBRD2 from cryptosporidium, cgd3_3190 HTML PDF
4LEC METTL21A Q8WXB1 Human Methyltransferase-Like Protein 21A HTML PDF
4LG1 METTL21D Q9H867 Human Methyltransferase-Like Protein 21D HTML PDF
4LG6 ANKRA2 Q9H9E1, Q9H0W5 Crystal structure of ANKRA2-CCDC8 complex HTML PDF
4LG7 MBD4 O95243 Crystal structure MBD4 MBD domain in complex with methylated CpG DNA HTML PDF
4LG8 PRPF19 Q9UMS4 Crystal structure of PRPF19 WD40 repeats HTML PDF
4LG9 TBL1XR1 Q9BZK7 Crystal structure of TBL1XR1 WD40 repeats HTML PDF
4LZ2 BAZ2A Q9UIF9 Crystal structure of the bromodomain of human BAZ2A HTML PDF
4MEN BRD4 O60885 Crystal Structure of the first bromodomain of human BRD4 in complex with a 5-methyl-triazolopyrimidine ligand HTML PDF
4MEO BRD4 O60885 Crystal Structure of the first bromodomain of human BRD4 in complex with a 2-methyl-quinoline ligand HTML PDF
4MEP BRD4 O60885 Crystal Structure of the first bromodomain of human BRD4 in complex with a 3-chloro-pyridone ligand HTML PDF
4MHV ETS2 P15036 Crystal structure of the PNT domain of human ETS2 HTML PDF
4MI0 EZH2 Q15910 Human Enhancer of Zeste (Drosophila) Homolog 2(EZH2) HTML PDF
4MR3 BRD4 O60885 Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazolinone ligand (RVX-OH) HTML PDF
4MR4 BRD4 O60885 Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazolinone ligand (RVX-208) HTML PDF
4MR5 BRD2 P25440 Crystal Structure of the second bromodomain of human BRD2 in complex with a quinazolinone ligand (RVX-OH) HTML PDF
4MR6 BRD2 P25440 Crystal Structure of the second bromodomain of human BRD2 in complex with a quinazolinone ligand (RVX-208) HTML PDF
4MTL METTL21C Q5VZV1 Human Methyltransferase-Like Protein 21C HTML PDF
4MVT PIAS3 Q9Y6X2 Crystal structure of SUMO E3 Ligase PIAS3 HTML PDF
4NG6 FDPS P14324 The effects of Lysine 200 and Phenylalanine 239 Farnesyl Pyrophosphate Synthase (FPPS) mutations on the catalytic activity, crystal structure and inhibition by nitrogen containing bisphosphonates HTML PDF
4NQM BRD4 O60885 Crystal Structure of the first bromodomain of human BRD4 in complex with a triazolo-phthalazine ligand HTML PDF
4NQN BRD9 Q9H8M2 Crystal Structure of the bromodomain of human BRD9 in complex with a triazolo-phthalazine ligand HTML PDF
4NR4 CREBBP Q92793 Crystal structure of the bromodomain of human CREBBP in complex with an isoxazolyl-benzimidazole ligand HTML PDF
4NR5 CREBBP Q92793 Crystal structure of the bromodomain of human CREBBP in complex with an isoxazolyl-benzimidazole ligand HTML PDF
4NR6 CREBBP Q92793 Crystal structure of the bromodomain of human CREBBP in complex with an oxazepin ligand HTML PDF
4NR7 CREBBP Q92793 Crystal structure of the bromodomain of human CREBBP in complex with an isoxazolyl-benzimidazole ligand HTML PDF
4NR8 BRD4 O60885 Crystal structure of the first bromodomain of human BRD4 in complex with an isoxazolyl-benzimidazole ligand HTML PDF
4NW2 CHD1 O14646, P03495 Tandem chromodomains of human CHD1 in complex with Influenza virus NS1 C-terminal tail trimethylated at K229 HTML PDF
4NW3 MLL Q03164 Crystal structure of MLL CXXC domain in complex with a CpG DNA HTML PDF
4NXJ PF14_0724 Q8IK82 Crystal Structure of PF3D7_1475600, a bromodomain from Plasmodium Falciparum HTML PDF
4NYV CREBBP Q92793 Crystal Structure of the Bromodomain of human CREBBP in complex with a quinazolin-one ligand HTML PDF
4NYW CREBBP Q92793 Crystal Structure of the Bromodomain of human CREBBP in complex with a dihydroquinoxalinone ligand HTML PDF
4NYX CREBBP Q92793 Crystal Structure of the Bromodomain of human CREBBP in complex with a dihydroquinoxalinone ligand HTML PDF
4O2W HERC1 Q15751 Crystal structure of the third RCC1-like domain of HERC1 HTML PDF
4O38 GAK O14976 Crystal structure of the human cyclin G associated kinase (GAK) HTML PDF
4O61 ALKBH5 Q6P6C2 Structure of human ALKBH5 crystallized in the presence of citrate HTML PDF
4O62 ZCWPW2 Q504Y3, P84243 CW-type zinc finger of ZCWPW2 in complex with the amino terminus of histone H3 HTML PDF
4O64 KDM2B Q8NHM5 Zinc fingers of KDM2B HTML PDF
4OCT HTML PDF
4OGI BRD4 O60885 Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor BI-2536 HTML PDF
4OGJ BRD4 O60885 Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor TG-101348 HTML PDF
4PWY CAMKMT Q7Z624 Crystal structure of a Calmodulin-lysine N-methyltransferase fragment HTML PDF
4PXW VPRBP Q9Y4B6 Crystal structure of human DCAF1 WD40 repeats (Q1250L) HTML PDF
4PY6 Pf-BRD3 Q8I240 Crystal Structure of bromodomain of PFA0510w from Plasmodium Falciparum HTML PDF
4PYZ USP7 Q93009 Crystal structure of the first two Ubl domains of Deubiquitylase USP7 HTML PDF
4PZI KMT2B Q9UMN6 Zinc finger region of MLL2 in complex with CpG DNA HTML PDF
4Q0N PBRM1 Q86U86 Crystal Structure of the fifth bromodomain of Human Poly-bromodomain containing protein 1 (PB1) in complex with a hydroxyphenyl-propenone ligand HTML PDF
4Q0O PBRM1 Q86U86 Crystal Structure of the fifth bromodomain of Human Poly-bromodomain containing protein 1 (PB1) in complex with a hydroxyphenyl-propenone ligand HTML PDF
4Q6F BAZ2A Q9UIF9 Crystal structure of human BAZ2A PHD zinc finger in complex with unmodified H3K4 histone peptide HTML PDF
4Q96 RPRD1B Q9NQG5 CID of human RPRD1B in complex with an unmodified CTD peptide HTML PDF
4QBM BAZ2A Q9UIF9 Crystal structure of human BAZ2A bromodomain in complex with a diacetylated histone 4 peptide (H4K16acK20ac) HTML PDF
4QN1 SHPRH Q149N8 Crystal Structure of a Functionally Uncharacterized Domain of E3 Ubiquitin Ligase SHPRH HTML PDF
4QNS Pf-GCN5 Q8IB67 Crystal structure of bromodomain from Plasmodium faciparum GCN5, PF3D7_0823300 HTML PDF
4QNY LdMAPK A0A3Q8ITZ9 Crystal structure of MapK from Leishmania donovani, LDBPK_331470 HTML PDF
4QPN METTL21B Q96AZ1 Crystal Structure of Human Methyltransferase-Like Protein 21B HTML PDF
4QPP PRMT6 Q96LA8 The Crystal Structure of Human HMT1 hnRNP methyltransferase-like protein 6 in complex with compound DS-421 (2-{4-[3-CHLORO-2-(2-METHOXYPHENYL)-1H-INDOL-5-YL]PIPERIDIN-1-YL}-N-METHYLETHANAMINE HTML PDF
4QQ4 MORC3 Q14149, P84243 CW-type zinc finger of MORC3 in complex with the amino terminus of histone H3 HTML PDF
4QQ6 SMN1 Q16637 Crystal Structure of tudor domain of SMN1 in complex with a small organic molecule HTML PDF
4QQD UHRF1 Q96T88 Crystal Structure of tandem tudor domains of UHRF1 in complex with a small organic molecule HTML PDF
4QQG KAT5 Q92993 Crystal structure of an N-terminal HTATIP fragment HTML PDF
4QQI ANKRA2 Q9H9E1, Q2KHR2 Crystal structure of ANKRA2-RFX7 complex HTML PDF
4QQK PRMT6 Q96LA8 Human HMT1 hnRNP methyltransferase-like protein 6 (S. cerevisiae) with GMS HTML PDF
4QQM (superseded by 6MEW) RFXANK O14593, Q2KHR2 RFXANK ankyrin repeats in complex with a RFX7 peptide HTML PDF
4QSP ATAD2 Q6PL18 Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with acetyl-lysine HTML PDF
4QSQ ATAD2 Q6PL18 Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) with bound DMSO HTML PDF
4QSR ATAD2 Q6PL18 Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) with bound MPD HTML PDF
4QSS ATAD2 Q6PL18 Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with N-Methyl-2-pyrrolidone (NMP) HTML PDF
4QST ATAD2 Q6PL18 Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with 1-methylquinolin 2-one HTML PDF
4QSU ATAD2 Q6PL18 Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with thymine HTML PDF
4QSV ATAD2 Q6PL18 Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with thymidine HTML PDF
4QSW ATAD2 Q6PL18 Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with 5-methyl uridine HTML PDF
4QSX ATAD2 Q6PL18 Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with 3'-deoxy thymidine HTML PDF
4QUT ATAD2 Q6PL18, P62805 Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) complexed with Histone H4-K(ac)12 HTML PDF
4QUU ATAD2 Q6PL18, P62805 Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) complexed with Histone H4-K(ac)5 HTML PDF
4R3H YTHDC1 Q96MU7 The crystal structure of an apo RNA binding protein HTML PDF
4R3I YTHDC1 Q96MU7 The crystal structure of an RNA complex HTML PDF
4RCI YTHDF1 Q9BYJ9 Crystal structure of YTHDF1 YTH domain HTML PDF
4RCJ YTHDF1 Q9BYJ9 Crystal structure of YTHDF1 YTH domain in complex with 5mer m6A RNA HTML PDF
4RFQ METTL18 O95568 Human Methyltransferase-Like 18 HTML PDF
4RG1 C9orf114 Q5T280 Methyltransferase domain of C9orf114 HTML PDF
4RG2 TP53BP1 Q12888 Tudor Domain of Tumor suppressor p53BP1 with small molecule ligand HTML PDF
4ROH (superseded by 5CQ2) ITCH Q96J02, Q9H3M7 Crystal Structure of tandem WW domains of ITCH in complex with TXNIP peptide HTML PDF
4ROI (superseded by 5DZD) ITCH Q96J02, Q9H3M7 Crystal Structure of WW4 domain of ITCH in complex with TXNIP peptide HTML PDF
4ROJ VAV2 P52735, Q9H3M7 Crystal Structure of the VAV2 SH2 domain in complex with TXNIP phosphorylated peptide HTML PDF
4RRE (superseded by 5DWS) ITCH Q96J02, Q9H3M7 Crystal Structure of ITCH WW3 domain in complex with TXNIP peptide HTML PDF
4RZ0 PfSET5 W7FLI1 Crystal Structure of Plasmodium falciparum putative histone methyltransferase PFL0690c HTML PDF
4TLG SEC14L4 Q9UDX3 Crystal structure of SEC14-like protein 4 (SEC14L4) HTML PDF
4TVR UHRF2 Q96PU4 Tandem Tudor and PHD domains of UHRF2 HTML PDF
4U7D RECQL P46063 Structure of human RECQ-like helicase in complex with an oligonucleotide HTML PDF
4UEG GYG2 O15488 Crystal structure of human glycogenin-2 catalytic domain HTML PDF
4UES (superseded by 5FTA) KCTD10 Q9H3F6 Crystal structure of the N-terminal BTB domain of human KCTD10 HTML PDF
4UIJ KCTD13 Q8WZ19 Crystal structure of the BTB domain of KCTD13 HTML PDF
4UML GDAP2 Q9NXN4 Crystal structure of ganglioside induced differentiation associated protein 2 (GDAP2) macro domain HTML PDF
4UN0 CDK12 O75909, Q9NYV4 Crystal structure of the human CDK12-cyclinK complex HTML PDF
4UNO ETV5 P41161 Crystal structure of the ETS domain of human ETV5 in complex with DNA HTML PDF
4URJ FAM83A Q86UY5 Crystal structure of human BJ-TSA-9 HTML PDF
4USD STK10 O94804 Human STK10 (LOK) with SB-633825 HTML PDF
4USE STK10 O94804 Human STK10 (LOK) with SB-633825 HTML PDF
4USF SLK Q9H2G2 Human SLK with SB-440719 HTML PDF
4UUC ASB11 Q8WXH4 Crystal structure of human ASB11 ankyrin repeat domain HTML PDF
4UUU CBS P35520 1.7 A resolution structure of human cystathionine beta-synthase regulatory domain (del 516-525) in complex with SAM HTML PDF
4UUV ETV4 P43268 Structure of the DNA binding ETS domain of human ETV4 in complex with DNA HTML PDF
4UYB SEC14L3 Q9UDX4 Crystal structure of SEC14-like protein 3 HTML PDF
4UYI SLX4 Q8IY92 Crystal structure of the BTB domain of human SLX4 (BTBD12) HTML PDF
4V06 TPH2 Q8IWU9 Crystal structure of human tryptophan hydroxylase 2 (TPH2), catalytic domain HTML PDF
4V0P MAGEA3 P43357 Crystal structure of the MAGE homology domain of human MAGE-A3 HTML PDF
4V24 SPHK1 Q9NYA1 Sphingosine kinase 1 in complex with PF-543 HTML PDF
4W9W BMP2K Q9NSY1 Crystal Structure of BMP-2-inducible kinase in complex with small molecule AZD-7762 HTML PDF
4W9X BMP2K Q9NSY1 Crystal Structure of BMP-2-inducible kinase in complex with baricitinib HTML PDF
4WSQ AAK1 Q2M2I8 Crystal Structure of Adaptor Protein 2 Associated Kinase (AAK1) in complex with small molecule inhibitor HTML PDF
4XCX HENMT1 Q5T8I9 METHYLTRANSFERASE DOMAIN OF SMALL RNA 2'-O-METHYLTRANSFERASE HTML PDF
4XDJ KCNK10 P57789 Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) in an alternate conformation (FORM 2) HTML PDF
4XDK KCNK10 P57789 Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) in complex with norfluoxetine HTML PDF
4XDL KCNK10 P57789 Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) in complex with a brominated fluoxetine derivative. HTML PDF
4XY8 BRD9 Q9H8M2 Crystal Structure of the bromodomain of BRD9 in complex with a 2-amine-9H-purine ligand HTML PDF
4XY9 BRD4 O60885 Crystal Structure of the first bromodomain of human BRD4 in complex with a 2-amine-9H-purine ligand HTML PDF
4XYA BRD4 O60885 Crystal Structure of the first bromodomain of human BRD4 in complex with a 2-amine-9H-purine ligand HTML PDF
4Y03 PB1 Q86U86 Crystal Structure of the fifth bromodomain of human PB1 in complex with salicylic acid HTML PDF
4YVD PLRG1 O43660 Crytsal structure of human Pleiotropic Regulator 1 (PRL1) HTML PDF
4YWQ RC3H1 Q5TC82 Crystal structure of the ROQ domain of human Roquin-1 HTML PDF
4YY8 PF3D7_1343700 A0A077LQB4 Crystal Structure Analysis of Kelch protein from Plasmodium falciparum HTML PDF
4YZ8 (superseded by 5UPD) WHSC1L1 Q9BZ95 Methyltransferase domain of human Wolf-Hirschhorn Syndrome Candidate 1-Like protein 1 (WHSC1L1) HTML PDF
4Z0O ZCWPW2 Q504Y3 CW-type zinc finger of ZCWPW2 with F78D mutation HTML PDF
4Z0R ZCWPW2 Q504Y3, P68431 Crystal Structure of the CW domain of ZCWPW2 mutant F78R in complex with histone H3 peptide HTML PDF
4Z3C TET3 O43151 Zinc finger region of human TET3 in complex with CpG DNA HTML PDF
5A15 KCTD16 Q68DU8 Crystal structure of the BTB domain of human KCTD16 HTML PDF
5A4R MMADHCMM Q99LS1 Crystal structure of a vitamin B12 trafficking protein HTML PDF
5A6R KCTD17 Q8N5Z5 Crystal structure of the BTB domain of human KCTD17 HTML PDF
5A9F POLQ O75417 Crystal structure of the Helicase domain of human DNA polymerase theta in complex with ADP HTML PDF
5A9J POLQ O75417 Crystal structure of the Helicase domain of human DNA polymerase theta, apo-form HTML PDF
5ACB CDK12 O75909, Q9NYV4 Crystal Structure of the Human Cdk12-Cyclink Complex HTML PDF
5AGA POLQ O75417 Crystal structure of the Helicase domain of human DNA polymerase theta in complex with AMPPNP HTML PDF
5AHR DCLRE1A Q6PJP8 Crystal structure of human DNA cross-link repair 1A, crystal form B HTML PDF
5AK7 PG1424PG Q9RQJ2 Structure of wt Porphyromonas gingivalis peptidylarginine deiminase HTML PDF
5AK8 PG1424PG Q9RQJ2 Structure of C351A mutant of Porphyromonas gingivalis peptidylarginine deiminase HTML PDF
5B8D HDAC6 Q9UBN7 Crystal structure of a low occupancy fragment candidate (N-(4-Methyl-1,3-thiazol-2-yl)propanamide) bound adjacent to the ubiquitin binding pocket of the HDAC6 zinc-finger domain HTML PDF
5C0M CCDC101 Q96ES7 Crystal structure of SGF29 tandem tudor domain in complex with a Carba containing peptide HTML PDF
5C4Q LdBPK-BRD A0A3Q8IW45 Crystal Structure Analysis of bromodomain from Leishmania donovani complexed with bromosporine HTML PDF
5C7M ITCH Q96J02, P0CG48 CRYSTAL STRUCTURE OF E3 LIGASE ITCH WITH A UB VARIANT HTML PDF
5C8G Tb427tmp.01.1830 D0A8L1 Crystal Structure Analysis of PP-BRD20 from Tb427tmp complexed with BI-2536 HTML PDF
5C8H ORC2 Q13416 Crystal structure of ORC2 C-terminal domain HTML PDF
5C96 (superseded by 5DF6) PTPN11 Q06124, Q9H3M7 Crystal structure of PTPN11 tandem SH2 domains in complex with a TXNIP peptide HTML PDF
5CLT GBE1 Q04446 Crystal structure of human glycogen branching enzyme (GBE1) in complex with acarbose HTML PDF
5CLW GBE1 Q04446 Crystal structure of human glycogen branching enzyme (GBE1) in complex with maltoheptaose HTML PDF
5CZG Tb427.10.7420 D0A3H5 Crystal Structure Analysis of hypothetical bromodomain Tb427.10.7420 from Trypanosoma brucei in complex with bromosporine HTML PDF
5DZC PvPKG A5K0N4 Crystal structure of the cGMP-dependent protein kinase PKG from Plasmodium Vivax - AMPPNP bound HTML PDF
5E1B NTMT1 Q9BV86, P18754 Crystal structure of NRMT1 in complex with SPKRIA peptide HTML PDF
5E1D NTMT1 Q9BV86, P18754 NTMT1 in complex with YPKRIA peptide HTML PDF
5E1M NTMT1 Q9BV86, P18754 Crystal structure of NTMT1 in complex with PPKRIA peptide HTML PDF
5E1O NTMT1 Q9BV86, P18754 Crystal structure of NTMT1 in complex with RPKRIA peptide HTML PDF
5E2A NTMT1 Q9BV86, P18754 Crystal structure of NTMT1 in complex with N-terminally methylated SPKRIA peptide HTML PDF
5E2B NTMT1 Q9BV86, P18754 Crystal structure of NTMT1 in complex with N-terminally methylated PPKRIA peptide HTML PDF
5E8R PRMT6 Q96LA8 Human HMT1 hnRNP methyltransferase-like protein 6 (S. cerevisiae) HTML PDF
5EPJ CBX7 O95931 Crystal Structure of chromodomain of CBX7 in complex with inhibitor UNC3866 HTML PDF
5EPK CBX2 Q14781 Crystal Structure of chromodomain of CBX2 in complex with inhibitor UNC3866 HTML PDF
5EPL CBX4 O00257 Crystal Structure of chromodomain of CBX4 in complex with inhibitor UNC3866 HTML PDF
5EQ0 CBX8 Q9HC52 Crystal Structure of chromodomain of CBX8 in complex with inhibitor UNC3866 HTML PDF
5FAI EMG1 Q92979 EMG1 N1-Specific Pseudouridine Methyltransferase HTML PDF
5FDP DDR1 Q08345 Structure of DDR1 receptor tyrosine kinase in complex with D2099 inhibitor at 2.25 Angstroms resolution. HTML PDF
5FDX DDR1 Q08345 Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution. HTML PDF
5FEA LdBRD19 A0A3S7XB61 Domain Swapped Bromodomain from Leishmania donovani HTML PDF
5FII PAH P00439 Structure of a human aspartate kinase, chorismate mutase and TyrA domain. HTML PDF
5G3Q WNK1 Crystal structure of a hypothetical domain in WNK1 HTML PDF
5GXH GEMIN5 Q8TEQ6 The structure of the Gemin5 WD40 domain with AAUUUUUG HTML PDF
5H9M SIAH2 O43255 Crystal structure of siah2 SBD domain HTML PDF
5HZM PRMT6 Q96LA8 Human HMT1 hnRNP methyltransferase-like protein 6 (S. cerevisiae) HTML PDF
5I3L DPF3 Q92784, P68431 DPF3b in complex with H3K14ac peptide HTML PDF
5II1 PB1 Q86U86 Crystal Structure of the fifth bromodomain of human polybromo (PB1) in complex with 1-methylisochromeno[3,4-c]pyrazol-5(3H)-one HTML PDF
5IID PB1 Q86U86 Crystal Structure of the fifth bromodomain of human polybromo (PB1) in complex with 2-(3,4-dihydroxyphenyl)-5-hydroxy-4H-chromen-4-one HTML PDF
5IN3 GALT P07902 Crystal structure of glucose-1-phosphate bound nucleotidylated human galactose-1-phosphate uridylyltransferase HTML PDF
5J39 TDRKH Q9Y2W6 Crystal Structure of the extended TUDOR domain from TDRD2 HTML PDF
5J3E THYN1 Q9P016 Crystal Structure of Human THYN1 protein in complex with 5-methylcytosine containing DNA HTML PDF
5K29 TbrBDF5 Q382J7 Trypanosoma brucei bromodomain BDF5 (Tb427tmp.01.5000) HTML PDF
5KH3 HDAC6 Q9UBN7 Crystal structure of fragment (3-(5-Chloro-1,3-benzothiazol-2-yl)propanoic acid) bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain HTML PDF
5KH7 HDAC6 Q9UBN7 Crystal structure of fragment (3-[6-Oxo-3-(3-pyridinyl)-1(6H)-pyridazinyl]propanoic acid) bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain HTML PDF
5KH9 HDAC6 Q9UBN7 Crystal structure of a low occupancy fragment candidate (5-[(4-Isopropylphenyl)amino]-6-methyl-1,2,4-triazin-3(2H)-one) bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain HTML PDF
5KKP PUS7 Q96PZ0 Crystal Structure of Human Pseudouridylate Synthase 7 HTML PDF
5KO4 TbrBDF1 Q38AE9 Bromodomain from Trypanosoma brucei Tb427.10.8150 HTML PDF
5KO9 HMCES Q96FZ2 Crystal Structure of the SRAP Domain of Human HMCES Protein HTML PDF
5L4Q AAK1 Q2M2I8 Crystal Structure of Adaptor Protein 2 Associated Kinase 1 (AAK1) in Complex with LKB1 (AAK1 Dual Inhibitor) HTML PDF
5L6W XX02LIMK1 P53667, P23528 Structure Of the LIMK1-ATPgammaS-CFL1 Complex HTML PDF
5L76 AASS Q9UDR5 Crystal structure of human aminoadipate semialdehyde synthase, saccharopine dehydrogenase domain (in apo form) HTML PDF
5L78 AASS Q9UDR5 Crystal structure of human aminoadipate semialdehyde synthase, saccharopine dehydrogenase domain (in NAD+ bound form) HTML PDF
5LUU BRD4 O60885 Structure of the first bromodomain of BRD4 with a pyrazolo[4,3-c]pyridin fragment HTML PDF
5LZK FAM83B Q5T0W9 Structure of the domain of unknown function DUF1669 from human FAM83B HTML PDF
5MPO MOCS2 O96033, O96007 Crystal structure of human molybdopterin synthase complex HTML PDF
5MQ1 BRD7 Q9NPI1 Crystal structure of the BRD7 bromodomain in complex with BI-9564 HTML PDF
5MQ4 PRKCBP1 Q9ULU4 Crystal Structure of the leucine zipper of human PRKCBP1 HTML PDF
5MR1 PIP3E Q8WWN9 Crystal structure of the Pleckstrin homology domain of Interactor protein for cytohesin exchange factors 1 (IPCEF1) HTML PDF
5NFJ TRMT10C Q7L0Y3 Crystal structure of the methyltransferase subunit of human mitochondrial Ribonuclease P (MRPP1) bound to S-adenosyl-methionine (SAM) HTML PDF
5NKP KLHL3 Q9UH77, Q9BYP7 Crystal structure of the human KLHL3 Kelch domain in complex with a WNK3 peptide HTML PDF
5NZW DCLRE1A Q6PJP8 Crystal structure of DNA cross-link repair protein 1A in complex with ceftriaxone HTML PDF
5NZX DCLRE1A Q6PJP8 Crystal structure of DNA cross-link repair protein 1A in complex with Ceftriaxone (alternative site) HTML PDF
5NZY DCLRE1A Q6PJP8 Crystal structure of DNA cross-link repair protein 1A in complex with Cefotaxime HTML PDF
5O1N AASS Q9UDR5 Crystal structure of human aminoadipate semialdehyde synthase, saccharopine dehydrogenase domain with N-[(2S)-2-Pyrrolidinylmethyl]-trifluoromethanesulfonamide bound HTML PDF
5O1O AASS Q9UDR5 Crystal structure of human aminoadipate semialdehyde synthase, saccharopine dehydrogenase domain with proline bound. HTML PDF
5O1P AASS Q9UDR5 Crystal structure of human aminoadipate semialdehyde synthase, saccharopine dehydrogenase. HTML PDF
5O1V WNK3 Q9BYP7 Crystal structure of WNK3 kinase domain in a monophosphorylated apo state (A-loop swapped) HTML PDF
5O21 WNK3 Q9BYP7 Crystal structure of WNK3 kinase domain in a monophosphorylated state with chloride bound in the active site HTML PDF
5O23 WNK3 Q9BYP7 Crystal structure of WNK3 kinase domain in a monophosphorylated apo state HTML PDF
5O26 WNK3 Q9BYP7 Crystal structure of WNK3 kinase domain in a diphosphorylated state and in complex with AMP-PNP/Mg2+ HTML PDF
5O2B WNK3 Q9BYP7 Crystal structure of WNK3 kinase domain in a diphosphorylated state and in a complex with the inhibitor PP-121 HTML PDF
5O2C WNK3 Q9BYP7 Crystal structure of WNK3 kinase and CCT1 didomain in a unphosphorylated state HTML PDF
5OCN FOXN1 O15353 Crystal structure of the forkhead domain of human FOXN1 HTML PDF
5OXG ACVR1 Q04771 Crystal structure of the ACVR1 (ALK2) kinase in complex with LDN-212854 HTML PDF
5OY6 ACVR1 Q04771 Crystal structure of the ACVR1 (ALK2) kinase in complex with cyclical inhibitor OD36. HTML PDF
5QHI FAM83B Q5T0W9 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000271a HTML PDF
5QHJ FAM83B Q5T0W9 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000709a HTML PDF
5QHK FAM83B Q5T0W9 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000010a HTML PDF
5QHL FAM83B Q5T0W9 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000551a HTML PDF
5QHN FAM83B Q5T0W9 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000622a HTML PDF
5QHO FAM83B Q5T0W9 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000010a HTML PDF
5QHP FAM83B Q5T0W9 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000554a HTML PDF
5QHQ FAM83B Q5T0W9 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000574a HTML PDF
5QHR FAM83B Q5T0W9 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000635a HTML PDF
5QIB HAO1 Q9UJM8 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of HAO1 in complex with FMOPL000388a HTML PDF
5T1G CBX1 P83916, P68431 chromo shadow domain of CBX1 in complex with a histone peptide HTML PDF
5T1I CBX3 Q13185, P68431 CBX3 chromo shadow domain in complex with histone H3 peptide HTML PDF
5TB6 CREBB Q92793 Structure of bromodomain of CREBBP with a pyrazolo[4,3-c]pyridin fragment HTML PDF
5TCK LdBDF5B A0A3Q8I8I6 Second Bromodomain from Leishmania donovani LdBPK.091320 complexed with Bromosporine HTML PDF
5TCM LdBDF5A A0A3Q8I8I6 First Bromodomain from Leishmania donovani LdBPK.091320 complexed with BI-2536 HTML PDF
5TEY METTL3-METTL14 Q86U44, Q9HCE5 Human METTL3-METTL14 complex HTML PDF
5TTF EHMT2 Q96KQ7 Crystal structure of catalytic domain of G9a with MS012 HTML PDF
5TTW EED O75530 Crystal Structure of EED in Complex with UNC4859 HTML PDF
5U9N Cp_cdg4_1340 Q5CQB7 Second Bromodomain of cdg4_1340 from Cryptosporidium parvum, complexed with bromosporine HTML PDF
5UBA RPUSD4 Q96CM3 Human RNA Pseudouridylate Synthase Domain Containing 4 HTML PDF
5UBB METTL11B Q5VVY1 Crystal structure of human alpha N-terminal protein methyltransferase 1B HTML PDF
5ULO YWHAZ P63104, Q9P0N9 Crystal Structure of 14-3-3 zeta in Complex with a Serine 124-phosphorylated TBC1D7 peptide HTML PDF
5V9I EHMT2 Q96KQ7 Crystal structure of catalytic domain of G9a with MS0105 HTML PDF
5V9J EHMT1 Q9H9B1 Crystal structure of catalytic domain of GLP with MS0105 HTML PDF
5VBB RPUSD1 Q9UJJ7 Human RNA Pseudouridylate Synthase Domain Containing 1 HTML PDF
5VBD USP09X Q93008 Crystal structure of a putative UBL domain of USP9X HTML PDF
5VBT UBH04 Crystal structure of a highly specific and potent USP7 ubiquitin variant inhibitor HTML PDF
5VC8 NSD2 O96028 Crystal structure of the WHSC1 PWWP1 domain HTML PDF
5VC9 CXXC4 Q9H2H0 Zinc finger of human CXXC4 in complex with CpG DNA HTML PDF
5W9Q MBD1 Q9UIS9 Zinc finger region of MBD1 in complex with CpG DNA HTML PDF
5W9S CXXC5 Q7LFL8 Zinc finger of human CXXC5 in complex with CpG DNA HTML PDF
5WBN HDAC6 Q9UBN7 Crystal structure of fragment 3-(3-Benzyl-2-oxo-2H-[1,2,4]triazino[2,3-c]quinazolin-6-yl)propanoic acid bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain HTML PDF
5WCJ METTL13 Q8N6R0 Crystal Structure of Human Methyltransferase-like protein 13 in complex with SAH HTML PDF
5YBJ KANK1 Q14678 Structure of apo KANK1 ankyrin domain HTML PDF
6ASB FBXL19 Q6PCT2 CXXC and PHD-type zinc finger regions of FBXL19 in complex with DNA HTML PDF
6ASD TET1 Q8NFU7 Zinc finger region of human TET1 in complex with CpG DNA HTML PDF
6B57 TDRKH Q9Y2W6 tudor in complex with ligand HTML PDF
6BY9 EHMT1 Q9H9B1 Crystal structure of EHMT1 HTML PDF
6C1A MBD2 Q9UBB5 MBD2 in complex with methylated DNA HTML PDF
6C1T MBD2 Q9UBB5 MBD2 in complex with a partially methylated DNA HTML PDF
6C1V MBD2 Q9UBB5 MBD2 in complex with double-stranded DNA HTML PDF
6CC8 MBD3 O95983 Crystal structure MBD3 MBD domain in complex with methylated CpG DNA HTML PDF
6CCG MBD3 O95983 Crystal structure MBD3 MBD domain in complex with methylated CpG DNA HTML PDF
6CCR GID4 Q8IVV7 Selenomethionyl derivative of a GID4 fragment HTML PDF
6CDG GID4 Q8IVV7 GID4 fragment in complex with a peptide HTML PDF
6CKO AF-10 - DOT1L P55197, F1Q4W7 Crystal structure of an AF10 fragment HTML PDF
6CNP MBD2 Q9UBB5 Crystal structure of MBD2 complex with methylated CpG island HTML PDF
6D1T MBD1 Q9UIS9 Complex of MBD1-MBD and methylated DNA HTML PDF
6D2L CARM1 Q86X55 Crystal structure of human CARM1 with (S)-SKI-72 HTML PDF
6DUB METTL11B Q5VVY1, P18754 Crystal structure of a methyltransferase HTML PDF
6DXH USP05 P45974 Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with 4-(4-tert-butylphenyl)-4-oxobutanoate HTML PDF
6DXT USP05 P45974 Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with 3-(5-phenyl-1,3,4-oxadiazol-2-yl)propanoate HTML PDF
6EDF FYN P06241 Fragment of a tyrosine-protein kinase HTML PDF
6EI2 B2M P04439, P61769, P30279 Crystal Structure of HLA-A68 presenting a C-terminally extended peptide HTML PDF
6EIX ACVR1 Q04771 Crystal structure of the kinase domain of the Q207E mutant of ACVR1 (ALK2) in complex with a 2-aminopyridine inhibitor K02288 HTML PDF
6EKK DENND1A Q8TEH3, Q15286 Crystal structure of GEF domain of DENND 1A in complex with Rab GTPase Rab35-GDP bound state. HTML PDF
6EL8 FOXN1 O15353 Crystal structure of the Forkhead domain of human FOXN1 in complex with DNA HTML PDF
6ELM WNK2 Q9Y3S1 Crystal structure of the human WNK2 CCT1 domain HTML PDF
6ES0 RIPK2 O43353 Crystal structure of the kinase domain of human RIPK2 in complex with the activation loop targeting inhibitor CS-R35 HTML PDF
6FBK WNK2 Q9Y3S1, Q9H4A3 Crystal structure of the human WNK2 CCT-like 1 domain in complex with a WNK1 RFXV peptide HTML PDF
6FCX MTHFR P42898 Structure of human 5,10-methylenetetrahydrofolate reductase (MTHFR) HTML PDF
6FNU MET12SC P46151 Structure of S. cerevisiae Methylenetetrahydrofolate reductase 1, catalytic domain HTML PDF
6G4Q XX01SUCLG1 P53597, Q9P2R7 Structure of human ADP-forming succinyl-CoA ligase complex SUCLG1-SUCLA2 HTML PDF
6G57 KCTD8 Q6ZWB6 Structure of the H1 domain of human KCTD8 HTML PDF
6GI6 ACVR1 Q04771 Crystal structure of the ACVR1 (ALK2) kinase in complex with a Quinazolinone based ALK2 inhibitor with a 5-methyl core. HTML PDF
6GIN ACVR1 Q04771 Crystal structure of the ACVR1 (ALK2) kinase in complex with an Quinazolinone based ALK2 inhibitor with a 4-morpholinophenyl solvent accessible group. HTML PDF
6GIP ACVR1 Q04771 Crystal structure of the ACVR1 (ALK2) kinase in complex with a Quinazolinone based ALK2 inhibitor with a 2, 5-dimethyl core. HTML PDF
6GMB HAO1 Q9UJM8 Structure of human hydroxyacid oxidase 1 bound with FMN and glycolate HTML PDF
6GMC HAO1 Q9UJM8 1.2 A resolution structure of human hydroxyacid oxidase 1 bound with FMN and 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole HTML PDF
6GPJ GMDS O60547 Crystal structure of human GDP-D-mannose 4,6-dehydratase in complex with GDP-4F-Man HTML PDF
6GPK GMDS O60547 Crystal structure of human GDP-D-mannose 4,6-dehydratase (E157Q) in complex with GDP-Man HTML PDF
6GPL GMDS O60547 Crystal structure of human GDP-D-mannose 4,6-dehydratase in complex with GDP-4k6d-Man HTML PDF
6GQD GALT P07902 Structure of human galactose-1-phosphate uridylyltransferase (GALT), with crystallization epitope mutations A21Y:A22T:T23P:R25L HTML PDF
6GWR DDR1 Q08345 Structure of the kinase domain of human DDR1 in complex with a potent and selective inhibitor of DDR1 and DDR2 HTML PDF
6MF9 cgd4_650 Q5CQH9 Crystal structure of CGD4-650 with compound BI2536 HTML PDF
6MLC KMT2C Q8NEZ4, P62805 PHD6 domain of MLL3 in complex with histone H4 HTML PDF
6N31 WDR12 Q9GZL7 WD repeats of human WDR12 HTML PDF
6NEY TcCLB.506755.120 A0A2V2W6E9 Crystal structure of TcBDF5, a bromodomain containing protein from Trypanosoma cruzi HTML PDF
6NFT USP05 P45974 Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with (4-oxoquinazolin-3(4H)-yl)acetic acid HTML PDF
6NFX MBTD1 Q05BQ5, Q9H2F5 MBTD1 MBT repeats HTML PDF
6NIM TcCLB.506553.20 A0A2V2V5V1 Trypanosoma cruzi - BDF2, TcCLB.506553.20, solved with bromosporine HTML PDF
6NP7 TcCLB.506553.20 A0A2V2V5V1 Crystal structure of Trypanosoma cruzi bromodomain BDF2 (TcCLB.506553.20) HTML PDF
6OE7 HMCES Q96FZ2 Crystal structure of HMCES cross-linked to DNA abasic site HTML PDF
6OEA HMCES Q96FZ2 Crystal structure of HMCES SRAP domain in complex with longer 3' overhang DNA HTML PDF
6OEB HMCES Q96FZ2 Crystal structure of HMCES SRAP domain in complex with 3' overhang DNA HTML PDF
6OGJ MECP2 P51608 MeCP2 MBD in complex with DNA HTML PDF
6OGK MECP2 P51608 MeCP2 MBD in complex with DNA HTML PDF
6OGN PRMT7 Q922X9 Crystal structure of mouse protein arginine methyltransferase 7 in complex with SGC8158 chemical probe HTML PDF
6P0Q WDR12 Q9GZL7 Crystal Structure of Ubiquitin-like Domain of Human WDR12 HTML PDF
6PBG COPA P53621 Crystal structure of WD-repeat domain of human coatomer subunit Alpha (COPA) HTML PDF
6PDM PRMT9 Q6P2P2 Crystal structure of Human Protein Arginine Methyltransferase 9 (PRMT9) HTML PDF
6PED N6AMT1-TRMT112 Q9Y5N5, Q9UI30 Crystal structure of HEMK2-TRMT112 complex HTML PDF
6PFL HUWE1 Q7Z6Z7 Crystal structure of Human HUWE1 WWE domain in complex with ADPR HTML PDF
6UHD (superseded by 6VO5) HAT1 O14929, P62805 Crystal structure of Human histone acetytransferas 1 (HAT1) in complex with isobutryl-COA and K12A mutant variant of histone H4 HTML PDF
6V2D CDYL2 Q8N8U2 Crystal Structure of chromodomain of CDYL2 in complex with inhibitor UNC3866 HTML PDF
6V3N CDYL2 Q8N8U2, P68431 Crystal structure of CDYL2 in complex with H3K27me3 HTML PDF
6V41 CDY1 Q9Y6F8, P68431 crystal structure of CDY1 chromodomain bound to H3K9me3 HTML PDF
6VCS UHRF1 Q96T88 SRA domain of UHRF1 in complex with DNA HTML PDF
6VTI PPP1R10 O55000 Solution NMR structure of the N-terminal domain of the Serine/threonine-protein phosphatase 1 regulatory subunit 10, PPP1R10 HTML PDF
6VYC WDR91 A4D1P6 Crystal structure of WD-repeat domain of human WDR91 HTML PDF
6WAJ NLE1 Q9NVX2 Crystal structure of the UBL domain of human NLE1 HTML PDF
7KLJ KIF21A Q7Z4S6 Crystal structure of the WD-repeat domain of human KIF21A HTML PDF
7KQQ WDR55 Q9H6Y2 Crystal structure of human WDR55 HTML PDF
7KYX CORO6 Q6QEF8 Crystal structure of human CORO6 HTML PDF
 
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